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Author: Jinfiniti Science

What Does Peak Performance Aging Look Like? Is Cognitive Aging Really a Fact of Life?

Peak performance aging is a radical concept that throws a pie in the face of traditional aging. The traditional theory of aging is that there is little that we can do to stop the slide. 

We’ve all heard accepted-aging statements: “Well, there’s nothing you can do about it. I guess we’re just getting old.” “Can’t teach an old dog new tricks.” “Aches and pains are all part of getting old.” “Aging comes for us all.” 

One leading thinker, Steven Kotler, a noted expert in the field of peak performance begs to differ.

Aging is a fact of life, but old is all a mindset.”

A NY Times bestselling author, journalist and flow researcher, Kotler explains further about the myth of uncontrollable aging in his research and his recent book, Gnar Country: Growing Old, Staying Rad.

“Ageism is the most socially acceptable stereotype1 in the world,” he said. “But it has radical consequences.”  He further explains, aging is a mindset,”A proper mindset towards aging is also a growth mindset. If you have a fixed mindset around aging, everything about lifelong learning is going to be worthless.”

When psychologist Mihaly Cskiszentmihalyi coined the term Flow in the 70s to explain the peak performance zone he discovered people could tap into, he discovered a unique psychological state like any other and inadvertently helped catalyze the positive psychology movement. 

When it comes to aging, the latest research indicates that not only is regularly activating flow state a key factor in long-term life satisfaction, it is also neuro-protective against cognitive decline (see George Valliant’s research at Harvard-citations will be on our blog). 

You may be wondering what all this may have to do with Jinfiniti, and we’ll get to that in a second. 

But first, here are a few things that happen when your body is in Flow State: 

  1. All six positive neurochemical cocktails are released.
  2. Life satisfaction goes up. 
  3. Cognitive decline slows and even reverses. 

The long slow route theory of aging states that skills decline as you age, therefore cognitive decline is inevitable. But new research that supports peak performance aging flys in the face of that with practical guidance on how to achieve peak performance aging. 

To avoid cognitive decline, the research says that you need to:  

  1. Solve the crisis of identity by the time you’re 30.

  2. Have match/fit quality by the time you’re in your 40s.

  3. In your 50s, you need to combat two things:

    1. Risk aversion. If you are risk averse, you are fearful which releases norephedrine, which then blocks . You need challenging, creative social experiences and should remain open, curious and explorative. 

    2. Physical fragility. According to Kotler, you do this through “challenging social activities that involve deliberate dynamic play in novel outdoor environments.” To protect against cognitive decline, you need neurogenesis, the birth of new neurons. You have 700 new neurons being made daily, with the majority of them being made in the hippocampus. 

So why is this important? In the hippocampus, your brain remembers novel outdoor experience as that is what your brain has been trained to do for thousands of years. 

What does a positive, even a growth mindset around aging look like?

Six neurochemical cocktails released in flow:

1. DOPAMINE

Drives desire, excitement, enthusiasm, sexual desire, curiosity, to test your limits

2. NOREPINEPHRINE

Brain’s version of adrenaline. Produces a huge increase in energy and alertness. When you’re obsessed with an idea, can’t stop thinking about the person you just met, then it’s activated

3. OXYTOCIN

Produces love, trust, friendship. It’s pro social. Underpins everything from long term bliss to cooperative businesses and relationships.

4. SEROTONIN

Calming, peaceful. Gives a mood lift. Shows up post meal with the desire to take a nap. Important for satisfaction and contentment

5 & 6. ENDORPHINS & ANANDAMIDE

Heavy duty stress & pain relievers. Replaces the weight of the day with euphoric happiness.

Kotler identifies five categories of functional fitness that need to be trained2 and maintained: strength, stamina, agility, balance and flexibility.

“These are all use it or lose it skills, if we want to retain our physical abilities late in life3,” he said.

He noted a study about aging conducted by Yale professor Becca Levy4 that proved there was a significant correlation in how people thought about aging and viewed themselves when exposed to negative stereotypes.

“This could be people saying, ‘You’re too old for this s- -t,’ or you telling yourself ‘You’re too old for this s- -t,’” he explained. “By the time they were 60, we see a 30% greater memory decline in people who have been exposed to negative stereotypes around aging. Literally, we’re killing each other with these ideas.”

So here’s how peak performance aging ties into what we’re about at Jinfiniti:

If you are suffering in one of the vital biomarkers that can precipitate and accelerate aging, then it dramatically diminishes your potential longevity and healthspan.

Just this week, I met a 35-year-old with significant health issues whom we may be able to help pre-empt by testing and more precisely diagnosing while also optimizing NAD levels, so it can happen at almost any age.

NAD deficiency affects your energy, which in turn, affects your drive and motivation to engage in peak-performance, anti-aging related activities. The sooner you start ensuring your NAD is optimized, the sooner you throttle back aging, thereby extending your healthspan immediately. 

If you happen to be 50+ years old, your NAD levels are likely not optimal unless you’ve been taking our Vitality ↑® NAD+ Booster for quite some time. According to extensive research, the average healthy 50-year-old has already lost 50% of their NAD levels. 

Here at Jinfiniti, our flagship NAD supplement, the Accuri® Vitality ↑® NAD+ Booster, is a patent-pending formulation that has been extensively tested in clinical studies by  hundreds of clinics and by thousands of consumers. It allows optimization of NAD in approximately 90% of users, a figure incomparable to any other NAD supplementation on the market. 

No other molecule comes close to helping your cells function optimally as much as NAD. 

This means that pain, inflammation, fatigue, brain function (obstacles to Flow State & peak performance aging) all decrease while mental clarity, stamina, recovery, energy, and youthfulness (ingredients of Flow State) all increase when NAD is optimized.

Hence why NAD optimization plays an inextricable link in achieving peak performance aging at the molecular level.

Whether you’re a pro athlete or you’re working in the corporate world, building a business, or raising a family, taking care of your cellular vitality is paramount to how you feel, how you perform but also how and whether or not you age.

That’s why NAD is  arguably the foundational molecule for all of life. Plus, if you are over 40 years old your NAD levels are essentially guaranteed to be deficient. So get one of our NAD tests and a bottle of Vitality ↑® NAD+ Booster to tune up your NAD levels. Better, yet, our NAD starter kit is a terrific value as it’s 2 tests and 2 Vitality ↑® NAD+ Boosters, so within two months we can verify that your NAD levels are up to optimal levels.

Lastly, if you’re interested in going deeper on health-related content, here are a few of our recent posts that you may want to read:

  1. Andrew Huberman is Wrong About NAD, NAD+ precursor & Longevity
  2. What Does Peak Performance Look Like? 
  3. 9 Powerful Benefits of Optimizing Your NAD
  4. Why Optimized, Precision Medicine is the Future

Citations:

Referenced Sources:

  1. https://nypost.com/2023/02/20/im-63-but-have-a-biological-age-of-43-heres-how-i-do-it/ ↩︎
  2. https://nypost.com/2017/01/19/you-office-job-is-literally-aging-you/ ↩︎
  3. https://nypost.com/2022/03/02/aging-faster-in-adulthood-linked-to-health-conditions-in-adolescence/ ↩︎
  4. https://medicine.yale.edu/news-article/harmful-effects-of-ageism-on-older-persons-health-found-in-45-countries/ ↩︎

Andrew Huberman is Wrong About NAD+, NR, and Longevity

Recently, Stanford neuroscientist Dr. Andrew Huberman (who has one of the top health podcasts in the world) did a 16-minute Q&A segment on NAD and its precursors. 

Overall, I respect his commitment to scientific accuracy and his standard of excellence with his approach.

However, I consider him under-informed and not a subject matter expert in this particular arena.

Here’s where Huberman is wrong about NAD+, NR, and longevity.


In this article, you’ll discover…

  • Why you should not trust Andrew Huberman’s opinion about NAD supplements and why his expertise may not fully cover the complexities of NAD research, potentially leading to overestimated benefits.
  • Discover why NAD IV treatments might not be as effective as Andrew Huberman suggests and how they could be draining your wallet without delivering the promised health benefits.
  • The only NAD supplement proven to boost levels by 200-300%, far exceeding the modest 20-40% increase seen with other NAD products.

Let’s start with where we agree with Dr. Huberman:

  1. NAD provides a noticeable increase in energy: Dr. Huberman takes NAD+ precursor daily because of the very noticeable improvement in energy. In his words, “It gives me a lot of sustainable physical and mental energy throughout the day. I noticed a decrease in energy when I stopped taking NAD+ precursor. While I wasn’t totally depleted, my energy was noticeably lower. As a 48-year-old, having great energy is important to me.”

  2. We need more data and research. There are countless studies, tens of millions of dollars and many different types of clinical trials underway and completed. But because NAD shows enormous promise and potential, we can’t do enough research fast enough. Plus, it takes years for many trials and studies to be completed. 

However, there are a few important points where I disagree with Dr. Huberman. I believe he is seeing an incomplete picture with regards to NAD and its role in so many of our body’s systems. 

Here’s where we disagree: 

  1. Optimal Levels of NAD Increase Lifespan by Increasing Healthspan: While there haven’t been conclusive studies done on humans to demonstrate that NAD extends lifespan, you’d be hard-pressed to find any conclusive clinical trials and studies on any molecule or nutrient that slows aging.  Furthermore, the six root causes of aging that are central to long term health are all influenced, if not directly affected, by NAD. If your NAD levels are deficient, your metabolic function suffers significantly, which we know intensifies and accelerates your aging as well as your likelihood of disease. 
  1. Supplements are fundamental to optimal health: He claims that supplements are NOT fundamental to life/health, which is obviously wrong. Most of us are deficient in multiple nutrients for one reason or another and supplementation is an invaluable way to boost and support our health, improving our healthspan and thereby extending our lifespan.
  1. NAD+ precursor clearly elevates NAD levels (especially Vitality ↑® NAD+ Booster): Huberman says he does not know if NAD+ precursor can elevate NAD.  He is ignoring all the publications and consumer data that NAD+ precursor can elevate NAD and the functional/clinical benefits. His statement is contradictory to his own experience that it gives him more energy with cellular energy being a fundamental aspect of good health. We see thousands of test results every year that conclusively demonstrate that your intracellular levels can be substantially increased, especially with our Vitality ↑® NAD+ Booster, of which no other supplement comes close to increasing NAD levels as effectively.
  1. NAD IV. There’s much that we don’t know about the effectiveness of intravenous NAD, but one thing we do know is that it has no measurable impact on raising the NAD levels in your blood. Within hours of getting an IV, your system has flushed out the NAD from your bloodstream. Huberman seems to believe that your NAD levels increase with NAD IV, which is not the case at least intracellularly though they do seem to increase in your plasma. Here’s a feature that RaisingNAD.com1 did on me where we discussed the research that indicates no perceptible impact to intracellular NAD though your cellular plasma NAD levels do seem to increase.

See our YouTube video this week comparing NAD IV vs. Vitality ↑® NAD+ Booster.

Many people do notice an increase in energy and reduction in anxiety for a time period ranging from several days to several weeks after an IV, and we also agree that NAD IVs are a very expensive (and even painful) way to increase NAD

Dr. Huberman deserves a thumbs-up for his overall approach and standard of scientific rigor. As a fellow scientist, I have served as a Division Chief of Experimental Pathology and Director of Research and was the founding Director for Biotechnology and Genomic Medicine, as well as the director of two core research facilities in Genomics, Proteomics, and Mass Spectrometry.

As a genetics researcher for over 40+ years, I have reviewed thousands of intracellular NAD tests, authored over 400-peer reviewed papers with an H-index of 76 and over 20,000 citations, and secured over $100 million dollars in research grants.

Here at Jinfiniti, our flagship NAD supplement, the Accuri® Vitality ↑® NAD+ Booster, is a patent-pending formulation that has been extensively tested in clinical studies by hundreds of clinics and by thousands of consumers. It allows optimization of NAD in approximately 90% of users, a figure incomparable to any other NAD supplementation on the market. 

I strongly disagree with both Dr. Andrew Huberman’s assessment of NAD and its precursors. His understanding of NAD and its precursors is far less than what’s currently available. He hasn’t had the privilege of thousands of intracellular NAD tests. 

As someone who has a deep and integral knowledge of NAD and its precursors, I have a much more expansive data set and perspective when it comes to NAD and its role in our health. It is my primary area of focus. 

With regards to neuroscience, Huberman is the expert. But as far as genetics and NAD are concerned, that’s my field of expertise

Vitality ↑® NAD+ Booster optimizes—not just improves—intracellular NAD for 90% of people alone, which no other NAD supplement can come close to promising.

While other brands increase NAD levels by 20-40% at best, we often see levels increase by 200-300% as we did with Doc Jen, a prominent doctor of physical therapy who loves the Vitality ↑® NAD+ Booster. We back it with a 60-Day Money-Back and Efficacy Guarantee. That’s because we back up our Vitality ↑® NAD+ Booster with testing, where all of the proof lies! 

I highly recommend testing your NAD levels to see where your levels are at and how much they need to be optimized. Jinfiniti’s intracellular NAD test is the only one of its kind in the world, and if you don’t already know where your levels are, it’s the best place to begin your optimization journey. 

Here are a few of our recent blog posts that you may be interested in reading regarding some of the science behind NAD, NAD precursors, and optimization leading to longevity: 

Lastly, as much as we know about NAD and its role in our health, there’s substantially more to be discovered, so I consider us very much in the early days of figuring out how to extend our lifespan. From the research and the experiential evidence I see every week with countless customers, NAD plays a vital role in extending our health span, life quality, and cellular vitality.

Referenced Sources:

  1. https://nadresearch.org/dr-she-describes-his-research-into-testing-and-supplementing-intracellular-nad-levels/ ↩︎
healthy food

The Dirty Secret 88% of Americans Struggle With

88% of Americans are struggling with a problem that can lead to a plethora of diseases and low-life quality: Metabolic dysfunction. 

It may not sound as terrible as autoimmune diseases, diabetes or heart disease, but guess what? It’s where all of those diseases come from. 

If this interests you as much as it does us, here is the number one way to decrease your metabolic dysfunction, age you quicker and increase your likelihood of diseases: 

Eat processed foods. 

The most important thing to know about your food is not what’s in it. It’s what has been done to it to make it processed. And yes, even your organic box of cereal that’s made with all-natural ingredients can still qualify as processed poison. 

Did you know that the USDA and the FDA are fully aware of the dangers of processed foods, yet continue to allow grocery stores to sell them? All while knowing that this so-called food is slowly poisoning the consumers of the United States.  

Food writer Mark Bittmas says that since food is defined as a “substance that provides nutrition and promotes growth” and poison is a “substance that promotes illness,” then “much of what is produced by industrialized agriculture is, quite literally, not food but poison.” 

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Dr. Robert Lustig compiles reasons for why Big Food’s processed diet is making us sick, and why it’s designed that way on purpose so that more sick people will require the drugs Big Pharma is offering. 

Dr. Lustig explains that of the eight pathologies (Heart Disease, Cancer, Stroke, Chronic Lower Respiratory Disease, Alzheimer’s, Diabetes, Influenza and Pneumonia, and Kidney Disease) that are most commonly killing us, none of them are curable via drugs. 

Five of them respond to exercise, which is vital; however, as Dr. Lustig says, you can’t outrun a bad diet.

The only thing that responds to all eight pathologies is food. Real food nourishes us on a metabolic level. That’s because our bodies know what to do with real food. It breaks it down into assimilable vitamins and minerals, which convert into cellular food like NAD, thus, increasing metabolic function. 

Real foods give your body essential vitamins and minerals that help your body create vitally important cellular food such as nicotinamide adenine dinucleotide (NAD)—one of the building blocks of nearly every cellular process in the human body. 

“If you do not fix your food, you continue to court disease and untimely death. If we do not fix our food, we will continue to court societal and planetary oblivion.”—Dr. Robert Lustig

In America, we spend 97.5 percent of our healthcare budget on individual treatment and only 0.5 percent of our budget on preventative care. 

In reality, this bad cycle of only reactively treating symptoms while continuing to under-nourish our cells leads to a collective, societal breakdown of our cellular health and metabolic dysfunction.

Thankfully, the people we serve are proactive, not reactive with their health. Here at Jinfiniti, we offer groundbreaking NAD blood testing and supplementation; two of the most powerful things you can do right now for your metabolic health.

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Restock on your Vitality ↑® NAD+ Booster or test your NAD levels here with the world’s only intracellular NAD test. Remember, our Vitality ↑® NAD+ Booster subscription option is always the best deal and will keep you from running out just as your metabolic health is getting better. 

Lastly, if you’re interested in going deeper on health-related content, here are a few of our recent posts that you may want to read:

  1. Why Optimized, Precision Medicine is the Future
  2. Andrew Huberman is Wrong About NAD, NAD+ precursor & Longevity
  3. What Does Peak Performance Look Like? 
  4. 9 Powerful Benefits of Optimizing Your NAD