Author: Jinfiniti Science

Can NAD Supplements Help You Lose Weight?

Written by Jinfiniti Science on November 9, 2024. Posted in NAD+, Glucose, NAD, NAD+ Precursors. No Comments on Can NAD Supplements Help You Lose Weight?

Losing weight can feel like an uphill battle, especially when you’re dealing with stubborn fat, a sluggish metabolism, and constant fatigue. If you’ve tried everything from restrictive diets to intense exercise regimens, yet still struggle to shed those extra pounds, the solution may lie in a vital compound called NAD+.

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme that plays a crucial role in cellular energy production, fueling a wide range of bodily functions, including metabolism. However, as we age, our natural NAD+ levels begin to decline, which can impact our ability to lose weight and maintain a healthy physique.

Fortunately, growing research suggests that supplementing with NAD+ precursors may hold the key to revitalizing your weight loss efforts. By boosting your NAD+ levels, you can potentially experience increased energy, enhanced fat-burning capabilities, and a faster, more efficient metabolism – all of which can contribute to successful and sustainable weight management.

So, can NAD supplements help you achieve your weight loss goals?

In this article, you’ll discover:

How NAD+ can help speed up your metabolism and burn fat more effectively.
The weight loss roadblocks NAD+ can help you break through for lasting results.
How NAD+ supplements can make managing your weight and metabolism easier and more sustainable.

NAD+ and Metabolic Function

a man with a measuring tape measuring his waist

NAD+ is a crucial molecule that powers our cells’ energy production. As a coenzyme, it supports several metabolic processes, including glycolysis, the citric acid cycle, and oxidative phosphorylation¹.

During glycolysis, NAD+ helps convert glucose (a type of sugar) into pyruvate, releasing energy in the process². This pyruvate then enters the next stages of energy production, where NAD+ helps extract even more energy from it.

For glycolysis to keep functioning, NADH (the reduced form of NAD+) must convert back into NAD+. This recycling ensures the process continues without a buildup of substances, supporting consistent energy production for all cellular activities, including metabolism.

In the citric acid cycle, NAD+ helps break down nutrients to produce high-energy electron carriers³. As nutrients are processed, NAD+ collects these high-energy electrons, which act like power boosts for our cells.

These electrons are then sent to the electron transport chain during oxidative phosphorylation, where their energy is used to produce ATP, the main energy currency of our body. This process is crucial for boosting metabolism and burning fat to manage weight effectively.

However, as we age, our bodies naturally see a decline in NAD+ levels. A 2022 study published in the journal Experimental Gerontology found that these levels can decrease by more than 50% from young adulthood to older ages⁴.

This decrease is alarming because low NAD levels can signal an energy deficiency⁵, making it harder for cells to metabolize nutrients effectively. Maintaining the right balance of NAD+ is crucial for optimal metabolic function and supporting healthy weight management.

With less NAD+, our energy production slows down, making it harder to burn calories efficiently. This slowdown can lead to weight gain or difficulty losing weight, contributing to those frustrating plateaus many experience in their fitness journeys.

NAD+ is also involved in regulating sirtuins⁶, enzymes that help manage fat metabolism and insulin sensitivity. As NAD+ levels fall, sirtuin activity can decrease, further hampering the body’s ability to regulate weight.

Moreover, NAD+ helps regulate autophagy, the process by which the body cleans out damaged cells. As we age, autophagy slows down⁷, and since NAD+ is needed for this to happen, lower levels can lead to a buildup of damaged cells. This accumulation can mess with your metabolism and contribute to weight gain.

NAD+ and Fat Tissues

NAD+ actively supports the functions of our fat tissues, specifically in white adipose tissue (WAT) and brown adipose tissue (BAT), which together enhance energy balance and optimize metabolic health.

WAT acts as an endocrine organ that secretes hormones like leptin, which regulate appetite and metabolism⁸. NAD+ influences the production and function of this hormone. For example, adequate NAD+ levels may improve leptin receptor sensitivity, which helps regulate appetite and reduce overeating.

Normal NAD+ levels are also necessary for the cells in WAT to respond well to insulin⁹, allowing glucose to be used for energy instead of being stored as fat. Low NAD+ levels can impair this process, contributing to insulin resistance and excess fat storage.

On the other hand, brown adipose tissue (BAT) contains a high concentration of mitochondria and burns energy to produce heat through thermogenesis¹⁰. This process is regulated by the protein UCP1 (uncoupling protein 1), which releases energy as heat instead of storing it.

NAD+ fuels BAT’s high metabolic rate and promotes the breakdown of stored fat for heat production. Activating BAT through NAD+ boosts thermogenesis, increasing overall energy expenditure¹¹, which can help with body weight management.

Another important role of NAD+ in fat tissues is its involvement in the “browning” of white fat. NAD+ helps trigger this transformation, where white fat cells convert into a more metabolically active form, similar to brown fat cells. As a result, these browned fat cells gain a higher mitochondrial density and can burn fat for energy.

A study published in Redox Biology shows that browning boosts fat’s metabolic activity¹², turning WAT from a passive storage site into an active fat-burning depot. This process can potentially reduce fat accumulation, especially in areas prone to stubborn fat storage.

The Science Behind NAD+ and Weight Loss

NAD+ is vital for cellular energy production. It helps convert glucose and fatty acids into usable energy within the mitochondria¹³, the powerhouses of cells. This energy drives everything from muscle function to body temperature regulation, making efficient energy conversion essential for managing weight.

The body’s metabolic flexibility, or the ability switch between burning fats and carbohydrates for fuel, is improved by NAD+, which supports energy conversion and activates metabolic enzymes.

While NAD+ helps support metabolic processes and energy expenditure, optimal levels are linked to healthier body composition¹⁴. Higher NAD+ levels are associated with better preservation of lean muscle mass, while low levels can contribute to fat accumulation.

Through its effects on cellular health and metabolic rate, NAD+ can help maintain a favorable balance between muscle and fat in the body, leading to a leaner physique over time.

Indeed, research shows that NAD+ may support weight management and improved body composition¹⁵. Healthy NAD+ levels also boost mitochondrial function and fat metabolism, which may contribute to weight management and metabolic health in the long run.

NAD+ also affects adiponectin, a hormone produced by fat cells that regulates glucose levels and breaks down fatty acids. Optimal NAD+ levels support adiponectin production¹⁶, which in turn improves insulin sensitivity and reduces inflammation.

This can help the body manage blood sugar better and reduce fat storage, both key factors in healthy weight management. So, while NAD+ itself might not directly burn fat, its role in reducing inflammation and supporting metabolic processes indirectly supports weight control and helps prevent metabolic dysfunctions that often accompany obesity.

Clinical Research on NAD for Weight Loss

a man and woman in lab coats looking at a test tube

Emerging research shows how NAD+ promotes weight loss and fat metabolism. While NAD+ has long been known as crucial for energy production, new studies reveal its potential to enhance the body’s ability to burn fat.

A study published in Frontiers in Nutrition involving 5,144 participants found that taking NAD+ precursors can lower Body Mass Index (BMI) and increase adiponectin levels.¹⁷ Specifically, people who took NAD+ supplements experienced a small yet significant reduction in BMI.

Another study published in the Journal of Nutritional Biochemistry looked at how nicotinamide (NAM) affects obesity in mice. The researchers found that NAM supplementation reduced fat mass and improved glucose tolerance¹⁸. It also increased mitochondrial proteins in fat tissue, suggesting that NAM boosts mitochondrial function, which is important for burning fat.

Moreover, NAM raised NAD+ levels by over 30% and enhanced glutathione production, supporting better metabolic function and easier weight management. Overall, NAM seems to reprogram how fat cells work to fight obesity-related issues.

Another study also found that NAD+ precursors can help with weight loss by improving insulin sensitivity and enhancing metabolic function. By boosting NAD levels, these precursors may help regulate energy expenditure and fat metabolism, making it easier for the body to burn fat.¹⁹

Overall, optimized NAD can help support better metabolic health and weight management and reduce obesity-related complications.

NAD+ Precursors and Their Weight Loss Effects

Of all the known NAD boosters, two of the most well-known are nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN).

A 2021 study found that NR supplementation was associated with reduced weight gain and preservation of muscle mass. NR also aided in weight reduction and increased lean mass relative to body fat. In rats on calorie restriction, NR reduced inflammation in the hypothalamus²⁰, a brain region important for weight control.

These findings suggest that NR, especially when combined with calorie restriction, could aid in weight management by promoting fat loss without sacrificing muscle, as well as by reducing certain inflammatory markers.

NMN, another direct precursor of NAD+, also shows promising effects on body composition and metabolism. A study published in the IUBMB Life journal demonstrated that NMN helped reduce fat mass, preserved lean muscle, and improved glucose tolerance²¹.

The researchers also found that NMN lowers blood lipid levels and reduces liver fat, mitigating inflammation in fat tissue and addressing fatty liver issues often seen with obesity. NMN appears to support a shift toward a healthier body profile.

On top of that, NMN’s ability to reduce fat tissue inflammation, improve insulin sensitivity, and boost insulin secretion could make it a helpful tool for balancing blood sugar and supporting a leaner body—both important for managing weight and metabolic health.

While NR and NMN are among the most studied NAD+ precursors, two other forms of vitamin B3, niacin and nicotinamide, also contribute to NAD+ production and deliver their own unique benefits to help with weight management and overall metabolic function.

Niacin assists in the body’s fat and sugar processing, supporting cellular health, which is essential for weight control. At higher doses, niacin can also improve blood triglyceride levels, helping prevent fat accumulation and promoting a balanced body composition.

In fact, a study published in Cell Metabolism found that niacin effectively boosts NAD+ levels in adults. At doses up to 1,000 mg daily, blood NAD+ levels increased up to eightfold, and participants experienced a significant liver fat reduction of up to 50%.²²

Nicotinamide, on the other hand, shows promise in metabolic function improvement through reducing fat mass and increasing lean muscle. In 2021, a study found that Nicotinamide improved weight management in mice²³. When given to them, Nicotinamide increased how much energy they burned and changed their body fat composition. The mice ended up with more brown and beige fat, which is good for burning calories.

In addition to well-known NAD+ precursors, D-ribose is another supplement worth trying. This naturally occurring sugar doesn’t directly increase NAD+ levels like the others, but it helps the body produce ATP, which in turn supports NAD+ production. This makes D-ribose another useful tool for boosting energy and metabolism.

At the end of the day, taking a holistic approach when using NAD precursors to improve metabolic function for weight loss is key to maximizing results. Jinfiniti’s Vitality ↑® NAD+ Booster exemplifies this by combining four synergistic ingredients: NMN, Creatine monohydrate, D-ribose, and nicotinamide.

This unique formulation supports cellular metabolism and energy to help your body lose weight efficiently. This clinically validated formulation ensures you’re not just supplementing but revitalizing your entire well-being by increasing NAD at the cellular level.

Does NAD IV Therapy Work for Weight Loss?

a woman measuring her waist with a measuring tape

NAD IV therapy has become a buzzword for those seeking weight loss, but it’s important to manage expectations. While NAD therapy boosts extracellular NAD levels, which can help with energy and metabolism, it shouldn’t be the sole strategy for shedding pounds.

When considering NAD supplements versus IV therapy, it’s important to understand their differences. NAD precursor supplements are easy to take regularly and support long-term cellular health, offering a gradual boost to NAD+ levels and metabolism over time. This makes them a good choice for steady, ongoing weight management.

In contrast, NAD IV treatment provides a higher, more immediate dose of NAD+, delivering quicker effects. While it can temporarily increase energy levels and metabolism, the impact on long-term fat loss or significant weight reduction may be limited without accompanying lifestyle changes.

Moreover, NAD IV therapy can be costly, and some people experience side effects like headaches, nausea, or dizziness. These effects are generally temporary but it’s important to be aware of them before undergoing treatment.

So, if you’re considering NAD injections for weight loss, it’s important to remember that it should be part of a broader strategy that includes a balanced diet and regular exercise. Ultimately, the choice depends on your personal health goals and budget.

Potential Side Effects of NAD Supplementation

a woman holding a glass of water and a glass of water

Current evidence points to NAD+ supplements being generally safe and well-tolerated, with some important caveats: long-term effects of high doses aren’t fully understood yet, and the supplement market’s limited regulation poses inherent risks.

Variable product quality and potential impurities remain ongoing concerns, making it important to opt for manufacturers that demonstrate their commitment to quality through independent testing.

How to Increase NAD Levels for Weight Loss

Increasing your NAD levels is a powerful way to support metabolism and make weight management easier, and there are a few simple steps to get started.

First up: diet. Choosing niacin-rich foods like vegetables, whole grains, and lean proteins can give your body the building blocks it needs to produce more NAD+. Even adding fermented foods, like kimchi and sauerkraut, can help out with a small NAD+ boost while benefiting gut health.

Next, staying active is key. Exercise—especially high-intensity and endurance workouts—naturally supports NAD production in your cells. Whether it’s a brisk walk, a run, or a strength session, regular movement keeps your energy high and your metabolism on point.

Making small lifestyle tweaks also goes a long way. Practicing intermittent fasting or occasional calorie restriction can jumpstart autophagy, clearing out old cells and ramping up NAD production. And managing stress through meditation or yoga can help prevent oxidative stress, allowing your NAD levels to stay stable.

For added support, consider NAD-boosting supplements that contain clinically proven precursors such as Vitality ↑® NAD+ Booster. These can help optimize your NAD+ levels, supporting your journey toward achieving your ideal weight and physique.

If you’re experiencing symptoms like fatigue, weight gain, or difficulty shedding pounds, it could be a sign of NAD deficiency. Taking an Intracellular NAD Test can help you assess your baseline levels, giving you a clearer picture before starting any interventions.

With regular testing, you can fine-tune your supplementation and track whether your current dosage or supplement is effectively supporting your weight loss goals.

TEST YOUR NAD LEVELS TODAY

Referenced Sources:

NAD Deficiency Symptoms: 6 Common Signs of Low NAD Levels

Written by Jinfiniti Science on October 28, 2024. Posted in NAD+, Depression and Anxiety, Energy and Fatigue, Memory Loss and Brain Fog, NAD, Skin Health, Sleep. No Comments on NAD Deficiency Symptoms: 6 Common Signs of Low NAD Levels

Feeling sluggish, mentally foggy, or struggling to keep up with your routine lately?

While it’s quite normal to feel this way from time to time, you shouldn’t take these frustrating signs for granted.

What seems like just another bad day could be a telltale sign that your NAD+ levels are running low.

Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme that plays a critical role in energy production, DNA repair, and overall health.

Unfortunately, NAD+ levels naturally decline with age and can be further affected by lifestyle factors, leading to a range of symptoms that are often overlooked.

So, what are these warning signs, and how can you optimize your NAD+ levels to stay healthy and active as you age?

In this article, we discuss:

Why your NAD levels are dropping faster than you think—and it’s not just because you’re getting older.

7 subtle signs of NAD deficiency that many people dismiss as “just part of aging,” but shouldn’t.

The red flags of severe NAD deficiency you can’t afford to ignore.

How to accurately detect low NAD levels in your body and the easiest, most effective ways to boost them naturally.

Understanding NAD+ and Why It Declines

Nicotinamide adenine dinucleotide, or NAD+, is an essential coenzyme found in every cell of our body. It plays a key role in several critical processes, including energy metabolism, DNA repair, and cellular signaling.¹

Essentially, NAD+ acts like a shuttle for electrons during metabolic reactions, helping to transform the food we consume into usable energy and supporting the production of ATP, which is the main energy currency for our cells.

Beyond just energy production, NAD+ also maintains the integrity of our DNA and regulates various cellular functions that keep us healthy.

Unfortunately, by the time we reach our 30s, our NAD+ levels start to decline. In fact, NAD+ can decrease by up to 50% as we age,² with noticeable reductions in the skin and other tissues.

This decline can be accelerated by factors like oxidative stress,³ unhealthy diets, and lifestyle choices, leading to symptoms that are often mistaken for the typical signs of aging.

But in reality, these may be early signs of low NAD+ levels, indicating that it’s time to take action and make necessary lifestyle changes to support your health and longevity.

Common Symptoms of NAD+ Deficiency

Below are six common health symptoms that indicate you may be deficient in NAD.

Fatigue and Low Energy

NAD is essential for energy metabolism. Think of it as the engine that powers your body, helping convert the food you eat into usable energy. However, when your NAD+ levels drop, it can disrupt your metabolism and may result in fatigue and low energy.

Your body might also struggle to produce ATP (adenosine triphosphate), which is your main source of energy. The result? You might feel sluggish and worn out. NAD+ also supports the proper functioning of enzymes that protect against oxidative damage.

When these protective enzymes can’t do their job because of low NAD levels, it creates an imbalance between harmful reactive oxygen species and protective antioxidants⁴ that can further drain your energy and leave you feeling even more fatigued.

Moreover, NAD+ is important in metabolizing carbohydrates, fats, and proteins. When your NAD+ levels are low, these metabolic pathways can become inefficient, leading to even more tiredness. For instance, if your body can’t break down fatty acids properly, it can accumulate unused substrates that sap your energy.

Not to mention, during physical activity, your muscles depend heavily on NAD+ for energy.⁵ If you’re low on NAD+, you might experience muscle weakness and decreased endurance, making even simple tasks feel much more challenging.

Cognitive Symptoms

NAD is also important for maintaining healthy cognitive function. When your levels drop, you might start to notice some cognitive symptoms, such as mental fog, memory lapses, and a general decline in sharpness.

This is because NAD+ is crucial for energy metabolism and mitochondrial function, both of which are essential for your brain to perform at its best. When NAD+ levels are low, the brain struggles to produce adenosine triphosphate (ATP)⁶—the energy that powers our cells—leading to sluggish thinking and that frustrating feeling of mental cloudiness or fatigue.

Research shows that a deficiency in NAD+ can worsen neuroinflammation and oxidative stress, both of which are harmful to cognitive health, potentially leading to increased neuronal damage and cognitive issues,⁷ such as forgetfulness and decreased mental agility.

Skin and Appearance Changes

Is your skin looking dry and dull despite your diligent skincare routine and healthy lifestyle? One hidden culprit could be low NAD+ levels.

Research shows that low NAD+ levels can hinder your skin’s ability to repair itself, particularly from damage caused by sun exposure. This impairment can result in more visible signs of aging, such as wrinkles and loss of elasticity.

Additionally, because NAD+ plays a key role in supporting mitochondrial function—the process that provides the energy your skin cells need to regenerate and stay vibrant⁸—low NAD+ levels can impede cell renewal. This leaves your skin looking tired, dull, and less radiant.

Poor Sleep Quality

Having trouble getting a restful night’s sleep? It could be more than just stress or a racing mind—it might actually be a deficiency in NAD+ levels.

As a coenzyme, NAD+ supports energy production and maintains healthy cells, including those involved in regulating your sleep cycle. When NAD+ levels decline, especially as we age, this drop can disrupt your sleep patterns.

Since NAD+ helps regulate key “clock” genes that control your sleep-wake cycle, it can throw off your body’s internal clock, or circadian rhythm,⁹ making it harder to fall asleep or stay asleep through the night.

Research also reported that NAD+ is essential for the synthesis of serotonin from tryptophan, a precursor amino acid.¹⁰ If NAD+ levels drop, this metabolic pathway can become inefficient, potentially leading to reduced serotonin and subsequently lower melatonin levels.

Therefore, you may experience sleep disturbances and increased fatigue due to inadequate melatonin production.

Mental Health and Mood Swings

Low NAD+ levels can significantly affect your mood and mental health, often manifesting as mood swings, irritability, anxiety, or even depression.

This occurs because NAD+ deficiency disrupts the balance of crucial neurotransmitters like serotonin, dopamine, and norepinephrine,¹¹ which are essential for regulating mood and emotional responses. As a result, you may experience persistent feelings of anxiety or sadness.

NAD+ is also important in activating sirtuins—proteins that help cells manage stress.¹² When NAD+ levels are low, sirtuins become less effective, which can contribute to mental health challenges like anxiety and irritability.

This makes it harder for your brain to cope with stress, intensifying emotional imbalances.

Metabolic Health Issues

NAD+ deficiency can lead to various metabolic problems,¹³ including weight gain, insulin resistance, and a higher risk of metabolic disorders.

NAD+ underpins key metabolic processes like glycolysis, the TCA cycle, and oxidative phosphorylation. When NAD+ levels drop, these processes become less efficient, disrupting energy metabolism and contributing to issues such as weight gain and insulin resistance.

Low NAD+ also affects enzymes involved in energy production, leading to reduced ATP synthesis and increased fat storage, particularly in the liver and fat tissue. This buildup of fat triggers inflammation, further worsening insulin resistance.

Moreover, NAD+ activates sirtuins, proteins that help regulate glucose and fat metabolism. When NAD+ levels are low, sirtuin activity declines, making it harder for the body to control blood sugar and insulin sensitivity,¹⁴ which raises the risk of type 2 diabetes.

People with low NAD+ levels are also more prone to developing metabolic conditions like diabetes and non-alcoholic fatty liver disease (NAFLD).

Severe NAD+ Deficiency Symptoms

People with NAD+ deficiency may also experience severe symptoms similar to pellagra, a condition caused by niacin deficiency.¹⁵

These symptoms indicate a critical lack of NAD+.

Dermatitis typically manifests as a scaly rash that worsens with sun exposure, indicating the body’s diminished capacity for healing due to low NAD+ levels. Diarrhea stems from impaired gut function and disrupted metabolism, which can lead to dehydration and poor nutrient absorption. Cognitive issues like memory loss and confusion arise because NAD+ is integral for brain cell energy production and neuronal health.

If left untreated, NAD+ deficiency can result in severe metabolic dysfunction,¹⁶ increasing the risk of serious conditions such as cardiovascular disease, diabetes, neurodegenerative disorders, and even death.

Cardiovascular Impact of NAD+ Deficiency

Low NAD+ levels can greatly increase the risk of cardiovascular diseases,¹⁷ hypertension, and reduced heart function. When NAD+ levels decline, vital processes like energy metabolism, DNA repair, and oxidative stress management become compromised, leading to a range of cardiovascular issues, especially hypertension.

Research published in the Signal Transduction and Targeted Therapy shows that hypertensive patients have a 44% lower NAD+ level in their peripheral blood mononuclear cells¹⁸ compared to those with normal blood pressure. This reduction is closely linked to impaired vascular function and elevated arterial pressure.

Additionally, NAD+ deficiency can cause mitochondrial dysfunction, which is crucial for maintaining cardiac energy metabolism.¹⁹ This leads to reduced ATP production and increased oxidative stress, both of which contribute to heart failure and other cardiovascular problems.

The enzyme CD38, which depletes NAD+, is often overactive in hypertensive individuals, further draining NAD+ levels and negatively affecting vascular health and heart function.

Beyond hypertension and weakened heart function, chronically low NAD+ levels can increase the risk of severe cardiovascular diseases like atherosclerosis and coronary artery disease,²⁰ which, if not addressed, can result in life-threatening events such as heart attacks and strokes.

NAD+ Deficiency in Specific Populations

While it’s common knowledge that NAD+ levels decline after the age of 30, certain groups are at a higher risk of experiencing a deficiency.

Obese individuals, for example, tend to have significantly lower NAD+ levels²¹ than those with a healthy weight. This is because excess fat triggers chronic inflammation and metabolic imbalances, which further deplete NAD+ levels.

Obesity is also associated with impaired NAD+ metabolism, increasing insulin resistance,²² and elevating the risk of type 2 diabetes and related conditions.

Genetic disorders also contribute to NAD+ deficiency risk. Individuals with conditions like congenital NAD deficiency disorder (CNDD)²³ experience inadequate NAD+ production, leading to developmental abnormalities and other health complications.

Genetic mutations that interfere with enzymes responsible for NAD+ synthesis reduce the availability of this vital coenzyme, contributing to congenital defects and increased health risks.

Given all these factors, the important question is: Are you NAD+ deficient? The only way to find out is to test.

How to Test if Your NAD Levels Are Low

Now that you understand the signs of NAD deficiency, how do you find out if your NAD levels are truly suboptimal?

At Jinfiniti, we prioritize precision over guesswork. That’s why we recommend the most reliable approach: testing your NAD+ levels directly.

Our Intracellular NAD Test gives you a clear picture of what’s happening inside your cells. We measure your actual NAD+ levels to help you see where you stand – whether they’re running low, sitting at a healthy baseline, or higher than average. With these insights, you can make smarter decisions about your NAD+ supplements and know if they’re really working for you.

TEST YOUR NAD LEVELS TODAY

How to Treat Low NAD Levels

If you suspect your NAD+ levels are low or have confirmed a deficiency through testing, there are several evidence-based approaches to increase your NAD+ levels naturally and through supplementation. The key is finding the right combination of lifestyle modifications and targeted support for your individual needs.

Research shows that regular exercise, particularly high-intensity training, naturally boosts NAD+ production. Combining this with a diet rich in B3 vitamins and stress management techniques can help optimize your body’s NAD+ levels while preventing excessive depletion of existing stores.

For those seeking intensive support, medical NAD+ therapies like IV infusions are available at specialized clinics. While these treatments can rapidly elevate extracellular NAD+ levels, they are costly and may cause side effects like flushing and headaches, requiring close medical supervision.

A more accessible and scientifically-validated approach is supplementation with NAD+ precursors.

Our High Purity NAD+ Precursor powder offers a premium-grade, pure form of NAD+ as a building block that your body can efficiently convert into active NAD+.

For those seeking enhanced results, our breakthrough Vitality ↑® NAD+ Booster takes supplementation to the next level by combining a clinically proven NAD+ precursor with synergistic ingredients. The strategic inclusion of creatine monohydrate helps stabilize cellular energy systems, while D-ribose and nicotinamide work together to optimize NAD+ synthesis pathways.

This unique formulation has been shown to increase NAD+ levels more effectively than single-ingredient supplements, providing total support for your cellular health and energy production.

With these strategies in hand, you’ll be on the right track to treating NAD deficiency and promoting longevity.

SHOP NAD+ SOLUTIONS

Referenced Sources:

NAD Supplements vs IV Therapy: Which is Best?

Written by Jinfiniti Science on October 25, 2024. Posted in NAD+, NAD. No Comments on NAD Supplements vs IV Therapy: Which is Best?

If you’ve been searching for ways to supercharge your energy or combat the signs of aging, you’ve probably come across NAD (nicotinamide adenine dinucleotide).

But here’s the real question: Should you take it as a supplement or opt for the more intensive IV therapy?

In this article, we’ll discuss:

The key differences between NAD supplements and NAD IV therapy.
The pros and cons of each option to find out which method fits best with your lifestyle and health goals.
Why some methods of NAD delivery are more effective than others and how absorption plays a crucial role.
How to tailor your NAD supplementation using personalized testing to match your unique health needs.

What is NAD?

NAD is a vital molecule found in every living cell of the human body. It serves as a coenzyme, meaning it assists enzymes in carrying out chemical reactions essential for life. NAD exists in two forms: NAD+ and NADH.

At its core, NAD+ is an electron courier. It shuttles electrons between different molecules during cellular metabolism, the process by which cells break down nutrients to generate energy.

The body produces NAD+ through three main pathways:

De novo synthesis: Creating NAD+ from scratch using amino acids.
Preiss-Handler pathway: Utilizing dietary niacin (vitamin B3) to form NAD+.
Salvage pathway: Recycling NAD+ components, primarily nicotinamide, after it has been used by enzymes.

In mammals, including humans, the salvage pathway is the primary source of NAD+. This efficient recycling process helps maintain adequate levels of this essential molecule.

NAD’s role extends beyond basic metabolism, influencing processes like DNA repair, gene expression, and cellular aging.

Types of NAD Treatments

Boosting NAD levels has become increasingly popular, and there are several types of NAD treatments available, each with its own advantages and considerations.

Oral NAD Supplements

NAD supplements come in various oral forms, including pills, capsules and pure powders. These products contain NAD precursors or related compounds designed to elevate NAD levels in the body. When ingested, a NAD+ supplement will pass through the digestive system and enter the bloodstream, where it circulates to cells throughout the body.

Many people choose oral NAD supplements as a straightforward way to increase their NAD levels. This method appeals to those who prefer to avoid intravenous treatments, offering a more familiar and less invasive approach to supplementation.

Discover Our NAD Supplements & Test Kits

NAD IV Therapy

NAD+ IV therapy is a new treatment where NAD+ is delivered directly into your bloodstream via an intravenous (IV) drip. During the session, a healthcare professional inserts a small IV line into your arm. The NAD+ solution is infused over a set period, allowing for direct absorption into your bloodstream. This bypasses the digestive system, leading to quicker availability of NAD+.

Dosages can vary depending on your needs, but typical sessions might range from 250 mg to 1,000 mg of NAD+. Treatments usually last between 1 to 3 hours, but some can go 4 hours or even longer depending on the dose and your needs. Many people opt for multiple sessions spread over weeks or months.

Other NAD Therapies

Beyond oral supplements and IV therapy, two additional methods for increasing NAD+ levels have gained some traction: injection therapy and nasal sprays.

NAD Injections

NAD+ injections offer a middle ground between oral supplements and IV therapy. This method delivers NAD+ directly into the bloodstream through intramuscular or subcutaneous injections.

NAD Nasal Sprays

NAD+ nasal sprays are a novel approach to NAD+ supplementation. These sprays deliver NAD+ through the nasal passages, claiming to deliver rapid absorption into the bloodstream.

Pros and Cons of NAD Supplements and IV Therapy

The quest for higher levels of NAD boils down to two main contenders: pills and supplements or intravenous therapy. Both have their benefits and downsides. Here we break down the pros and cons of NAD supplements versus IV drips, so you can figure out which method is best for cellular vitality.

Effectiveness

The effectiveness of NAD supplements or IV therapy depends largely on how well the body absorbs and utilizes the different delivery methods.

NAD supplements or precursors are compounds that can be efficiently taken up by cells and converted into NAD+ through various intracellular pathways. Once inside the cell, these precursors are metabolized to increase intracellular NAD+ levels. NAD precursors increase intracellular NAD+ levels by feeding into biosynthetic pathways, thereby supporting various NAD+ dependent processes.

Unlike NAD+ precursors, which are converted into NAD+ within cells, the primary action of NAD+ IV therapy is believed to be extracellular, influencing immune responses, inflammation, and cellular signaling¹ rather than directly increasing intracellular NAD+ levels.

Oral supplements are generally well-absorbed but may take longer to produce noticeable effects. In contrast, IV therapy introduces NAD+ directly into the bloodstream, resulting in more rapid onset of effects.

While IV treatments can provide a quick boost, their effects may be short-lived. This is due to several factors:

Rapid Clearance: NAD+ is quickly eliminated from the plasma, often within two hours of infusion.
Cellular Penetration: The relatively large size of NAD+ molecules can impede their ability to cross cell membranes efficiently.
Dosage Considerations: The amount and frequency of NAD+ administration significantly impact its effectiveness.

Oral NAD+ precursors offer a more consistent and sustained approach to increasing NAD+ levels. A 2019 study² demonstrated that oral supplementation can effectively elevate whole blood NAD+ levels over time:

Dose	NAD+ Increase
100 mg	22%
300 mg	51%
1000 mg	142%

These results were observed after two weeks of supplementation.

Despite its rapid clearance from the bloodstream, NAD IV therapy may still have potential benefits for certain medical conditions, particularly some neurological and infectious diseases.

To maximize the benefits of NAD+ supplementation, it’s important to consult with a healthcare provider to determine the most appropriate method and dosage regimen for individual needs and health goals.

Convenience

Supplements are generally the easier option in terms of convenience. You can take them as pills or mix a powder into a drink, making them a quick addition to your daily routine. No special setup or assistance is needed, so you can easily incorporate them into your day.

In contrast, IV therapy requires you to visit a clinic or healthcare professional. This involves scheduling an appointment and waiting, which can be less convenient if you have a busy lifestyle. The procedure typically spans several hours, during which the patient must remain relatively stationary.

The time investment for each method differs significantly:

Oral supplements: Consumption takes mere seconds
IV therapy: Sessions last between 1 to 4 hours or more

This time disparity can be a deciding factor for individuals with demanding schedules or limited flexibility in their daily routines.

In terms of availability, supplements win hands down. Oral supplements are widely available through retail stores and online platforms. IV therapy is limited to specialized clinics, which may not be present in your geographic area.

If convenience is a top priority for you, oral supplements offer a simpler, quicker, and more accessible option compared to NAD IV infusion.

Cost

Generally, dietary supplements are much more affordable. A typical bottle of NAD+ supplements can cost anywhere from $20 to $150, depending on the brand and dosage.

On the other hand, IV treatments can range from $150 to $500 per session. That can go even higher in expensive cities or at high-end clinics with state-of-the-art equipment. Add-ons like vitamins, minerals, or hydration boosters can also push up the price, so it’s worth checking what’s included before you book!

This price difference makes supplements a more accessible choice for daily or regular use. While supplements are more wallet-friendly, it’s also important to think about the long term.

If you’re considering regular IV therapy, those costs can add up quickly. For example, if you plan to have one treatment a month, that could mean spending anywhere from $1,800 to $6,000 a year.

The price disparity between these methods is substantial:

Method	Cost per Unit	Estimated Annual Cost (Monthly Use)
Oral	$20-$150/bottle	$240-$1800
IV	$150-$500/session	$1,800-$6,000

It’s essential to evaluate how often you intend to receive these treatments and whether they fit your budget in the long run. Your decision should take both immediate and ongoing expenses into account.

Safety and Side Effects

Supplements are generally safe and well tolerated, particularly in the forms of NAD precursors when taken at recommended doses. Studies have shown that they have a favorable safety profile and are relatively safe for use as a dietary ingredient³.

A study conducted in Japan found that a single oral dose of NAD precursor supplement up to 500 mg is safe for healthy men. Researchers observed no significant changes in vital signs like heart rate, blood pressure, or body temperature.⁴

However, for some individuals, they can experience common side effects like muscle pain, fatigue, sleep disturbances, and headaches⁵. These symptoms are usually short-lived and resolve quickly.

IV therapy, while highly effective for certain conditions, also carries additional risks.⁶ Patients may experience pain, bruising, or swelling at the site of infusion. Some individuals have reported additional NAD IV therapy side effects that impact the entire body, including headaches, fatigue, and nausea. These reactions can differ in intensity from person to person.

In rare cases, IV therapy can lead to serious complications, like infections or allergic reactions⁷.

Additionally, NAD IV therapy has been linked to higher levels of high-sensitivity C-reactive protein (hs-CRP), a marker of inflammation. Our research has found that about 70% of people who receive NAD IV therapy experience a 3- to 10-fold increase in hs-CRP levels, which can trigger an inflammatory response in some individuals.

Elevated hs-CRP levels are assoicated with an increased risk of cardiovascular (CV) events and atherosclerosis⁸. Therefore, monitoring hs-CRP levels and finding effective ways to manage inflammation is crucial for keeping patients safe during and after treatment.

Before starting either treatment, it’s also important to consider contraindications. Certain medical conditions can also make these therapies unsuitable.

Also, keep in mind that age can play a role. Older adults might respond differently due to various health issues or changes in metabolism. If you’re pregnant or breastfeeding, it’s also important to consult your healthcare provider as well, since the effects of NAD therapies in these cases aren’t fully understood yet.

Always take the time to discuss any new supplements or therapies with your healthcare provider. They can help ensure that whatever you choose is a safe fit for your individual health needs and circumstances.

Staying informed and cautious is key!

Choosing Between NAD Supplements or IV Therapy

An image of a man helping his father take supplements

NAD supplements provide a convenient and accessible method for long-term NAD support. These supplements are typically taken daily and can be easily integrated into existing routines. Clinical data suggests that oral NAD precursors can effectively raise intracellular NAD levels over time.

Benefits of NAD Supplements:

Can increase intracellular NAD+
Convenience of at-home use
Lower cost compared to IV therapy
Suitable for long-term, consistent use
Minimal risk of complications

Considerations:

Slower onset of effects
Potential for reduced bioavailability due to digestive processes

IV NAD therapy delivers NAD directly into the bloodstream, bypassing the digestive system. This method allows for rapid absorption and potentially higher bioavailability.

Benefits of NAD IV Therapy:

Rapid onset of effects
May be beneficial for acute conditions or rapid recovery

Considerations:

Requires clinical administration
Higher cost per treatment
Time-intensive procedure
Potential for adverse reactions
Influences signaling and metabolism outside the cell

The decision between oral supplements and IV therapy should be based on individual health needs, goals, and practical considerations.

Oral Supplements May Be Preferable For:

General wellness and anti-aging support
Long-term NAD maintenance
Those seeking a cost-effective, convenient option

IV Therapy May Be More Suitable For:

Individuals with acute health concerns requiring rapid intervention
Those with conditions affecting nutrient absorption
Athletes or individuals recovering from intense physical exertion

In some cases, a combination approach may be beneficial. For example, initiating treatment with IV therapy rapid delivery of extracellular NAD+, followed by oral supplementation to increase intracellular NAD+ levels and provide sustained benefits.

If you’re unsure about your current NAD levels, our intracellular NAD test can provide valuable insight and help you tailor your approach. Understanding your NAD status can guide your decision on whether to start with supplements, IV therapy, or a combination of both.

TEST YOUR NAD LEVELS TODAY

Frequently Asked Questions

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What are the benefits of NAD supplements?

NAD supplements offer potential long-term health benefits. NAD precursors have been shown to boost cellular energy production and support the body’s repair mechanisms. Research suggests they may contribute to slowing certain aspects of biological aging.

Are NAD Supplements as Effective as IV?

NAD+ IV therapy offers potential benefits for individuals with conditions like dementia, addiction, Lyme disease, and long COVID. This treatment delivers a high dose of NAD+ directly into the bloodstream, providing rapid but short-term relief. However, the effects are temporary, and the therapy requires administration by healthcare professionals in clinical settings.

For long-term benefits, including improved energy, performance, and longevity, intracellular NAD+ levels need to be increased. Oral NAD+ precursor supplements, available in pill or powder form, offer a more practical and sustainable approach. These supplements can be easily incorporated into daily routines and are designed to boost intracellular NAD+ levels over time.

Who should avoid or take NAD supplements?

Aging adults might find these supplements helpful as NAD levels naturally decline with age, potentially supporting cellular energy production and DNA repair. Athletes and fitness enthusiasts may be drawn to NAD’s role in energy metabolism, which could enhance physical performance and recovery. Individuals with specific health concerns, such as conditions linked to mitochondrial dysfunction or metabolic disorders, might also benefit from NAD supplementation.

However, certain groups should exercise caution. Pregnant or nursing women should avoid NAD supplements due to limited research on their effects during pregnancy and lactation, unless directed by a healthcare provider. Individuals with liver disease, kidney problems, or certain types of cancer should consult their doctor before use, as these supplements may interact with their condition or treatment.

Discover our NAD test kit to determine your levels and personalize your supplementation.

Discover Your NAD+ Levels with Jinfiniti

Curious about your NAD+ levels?

Jinfiniti offers an easy way to find out where you stand.

Understanding your NAD+ status can help you tailor your health approach, whether you’re aiming for energy boosts, better recovery, or overall wellness.

Our testing process is simple and provides valuable insights that can inform your next steps, whether you choose supplements, IV therapy, or both.

Discover your NAD+ levels with Jinfiniti today and discover your way to a more vibrant life. Knowing your body’s needs is the first step toward optimizing your health journey!

Referenced Sources:

NAD IV Therapy Side Effects: What are the Risks?

Written by Jinfiniti Science on October 18, 2024. Posted in NAD+. No Comments on NAD IV Therapy Side Effects: What are the Risks?

NAD IV therapy promises incredible results, from boosting energy to supporting anti-aging.

But is it too good to be true?

While the benefits sound great, there are common side effects of NAD therapy, from minor discomfort to serious complications, that you shouldn’t ignore.

Are the risks really worth it?

In this article, we’ll dive into:

The hidden safety concerns and side effects of NAD IV therapy that most people don’t talk about.
Critical factors you should consider before deciding if NAD IV therapy is right for you.
A safer alternative to NAD IV therapy that delivers results more efficiently without the downsides.

Recent studies show that by middle age, your NAD levels may drop to half of what they were in your youth¹. This decline can impact everything from your energy to how quickly you recover from stress.

It’s no surprise that NAD IV therapy has been gaining popularity as a quick fix for restoring vitality and slowing down the aging process. But with any growing trend comes important questions, particularly around safety.

Is NAD IV therapy as risk-free as it sounds? While the claims are exciting, it’s important to look at both sides, hence we’ll also dig into the risks and side effects in this article.

What is NAD IV Therapy?

Imagine having a “battery” in every cell of your body, constantly fueling your energy, repairing DNA, and keeping everything functioning smoothly. That’s the role of NAD (Nicotinamide Adenine Dinucleotide), a coenzyme essential for cellular health.

As we age, our NAD levels start to dip, leaving many of us feeling fatigued, recovering more slowly, and even noticing changes in our mental clarity.²

That’s where NAD supplementation comes into play, with many people turning to NAD IV therapy to help recharge those cellular “batteries.” NAD IV therapy involves infusing NAD directly into your bloodstream through an IV drip, bypassing the digestive system for quicker, more efficient absorption. The treatment typically lasts around four hours or longer, allowing the NAD to enter your body slowly while you relax.

Advocates of NAD IV swear by its benefits: increased energy, sharper focus, improved mood, and even anti-aging effects. Some even say it aids in addiction recovery, boosts athletic performance, and helps with cellular repair.

Common Safety Concerns of NAD Therapy

While many people report positive experiences with NAD IV treatment, there are some risks to consider, especially if the treatment isn’t administered properly, including:

Infection

Any time you’re dealing with an IV, there’s a risk of infection.³

Since the skin is punctured, bacteria can enter your bloodstream if the equipment isn’t properly sterilized. To reduce this risk, it’s important to have the treatment administered by trained professionals in a clean, medical setting.

Vein Irritation

Some people experience irritation or inflammation around the injection site.⁴

This could be due to the needle size, the frequency of treatments, or simply how your body reacts to the IV. While it’s usually minor and resolves on its own, it can still be uncomfortable.

Incorrect Dosage

Getting the dosage right with NAD IV therapy is crucial. Too little, and you may not experience the full benefits. Too much, and you could feel nauseous or dizzy.

A qualified practitioner will know the correct dosage for your body and specific needs.

Improper Administration

IV therapy requires precision. The placement of the IV, the dosage, and the flow rate all need to be exactly right.

If the person administering the treatment lacks experience, things can go wrong. You could end up with a poorly inserted IV or air bubbles in the line, which could lead to complications.⁵

Quality and Sourcing of NAD Products

Not all NAD products are created equal. The quality and purity of the NAD solution being used are vital to ensure you get the best results with minimal risk.

It’s important to choose a clinic that uses high-quality NAD sourced from reputable suppliers. If you’re given an inferior product, you could miss out on the benefits—or worse, face unwanted side effects.

What are the Side Effects of NAD IV Therapy?

Like any treatment, NAD IV therapy can come with its own set of side effects. While they’re usually mild, it’s important to be aware of what you might encounter during or after your session.

Common Short-Term Side Effects

Most people who try NAD IV therapy report mild side effects that tend to go away quickly. These can include nausea, flushing, and dizziness during or shortly after the treatment.

Some also report muscle cramping or chest tightness as the body adjusts to the NAD infusion. Though these milder symptoms typically fade after the session, they can be uncomfortable while they last.

Possible Long-Term Side Effects

While NAD IV therapy shows promise, there are concerns about its long-term effects, especially with frequent or high-dose intravenous treatments.

Flooding the body with excessive NAD, sometimes up to ten times the normal range, could disrupt its natural balance. This is a particular concern with unregulated IV bars, where dosage and frequency may not be carefully monitored.

While NAD+ is vital for various cellular processes, excessively high levels of NAD+ could potentially lead to adverse effects such as mitochondrial dysfunction or sirtuin overactivation.

NAD IV therapy has also been observed to cause a significant increase in high-sensitivity C-reactive protein (hs-CRP) levels in a substantial portion of recipients. Specifically, about 70% of individuals undergoing NAD IV therapy experience a 3- to 10-fold increase in hs-CRP, which is an acute phase reactive protein that indicates inflammation. To safeguard patient well-being, it is recommended to monitor hs-CRP levels and implement effective strategies to control inflammation.

If you are concerned about levels of inflammation, our at-home inflammation test kit, the AgingSOS® Senescence & NAD Panel, can help you reveal your inflammation status and take appropriate action.

AgingSOS® Senescence & NAD Panel

The Safest Approach to NAD IV Therapy

If you’re considering NAD IV therapy, safety should be your top priority. Here are a few key steps to ensure a safe and effective experience:

Choose a Qualified Provider

Your first step should be finding the right provider. Look for a licensed and experienced practitioner who specializes in NAD IV therapy.

Ask about their qualifications, experience with NAD treatments, and the safety protocols they follow. A reputable provider will gladly answer your questions and ensure you feel comfortable before moving forward.

Evaluate Your Health

Before starting any NAD IV therapy, it’s crucial to get a thorough health evaluation. Your provider should review your medical history, current medications, and any existing health conditions.

This helps determine whether NAD therapy is safe for you and allows them to tailor the treatment to your specific needs. Skipping this step could increase the risk of complications.

Monitor Your NAD Levels Regularly

To get the most out of NAD IV therapy and minimize risks, it’s also important to monitor your NAD levels.

The most effective way to do this is using an Intracellular NAD test, which measures the NAD levels within your cells. Keeping track of these levels during and after your sessions helps avoid issues like overdosing or underdosing.

This ongoing evaluation allows your practitioner to adjust your treatment for optimal results.

Test Your NAD Levels Today

Oral NAD Supplements: A Safer Alternative to NAD IV Treatment

While NAD IV therapy is popular for its quick delivery, it’s not the only option for boosting NAD levels. In fact, many people opt for an oral NAD+ supplement due to safety and convienience.

One big difference is how they work.

NAD IV therapy directly introduces the coenzyme into the bloodstream, but it is quickly metabolized and excreted, resulting in a short-lived effect.

Oral supplements, such as sublingual NAD powder, get absorbed by your cells and work from the inside out, helping to increase your body’s NAD+ levels gradually and sustainably. Plus, they’re much easier on the wallet and your schedule.

NAD IV can be both pricey and time-consuming, often costing hundreds per session and taking up to four hours or even more. In contrast, supplements are way more budget-friendly and easy to take, whether you’re at home or on the move. They fit right into your daily routine without any hassle.

Discover Our NAD Optimization® Supplements

Final Thoughts: Is NAD IV Therapy Safe?

NAD IV therapy has its benefits, but it’s not without risks. You might experience mild side effects like nausea or dizziness, or more serious issues like infections.

Safety is a big deal, especially if you’re thinking about using it long-term. It’s important to weigh these risks and talk to a qualified provider about whether it’s right for you. Take your time to weigh the pros and cons and find out if it suits your needs.

Also, don’t overlook safer alternatives like oral supplements. They work at the cellular level, naturally boosting NAD without the risks tied to IV treatments.

They also offer a more consistent, long-term boost, fueling your energy and overall health. Plus, you can take them anywhere, anytime, making them a hassle-free part of your daily routine.

So, if you’re seeking an effective, low-risk option to optimize your NAD levels and overall well-being, oral supplements may just be the better choice.

The best part? You can start today—without the needles or lengthy appointments.

Referenced Sources

NAD IV Therapy Cost: How Much Should You Expect to Pay?

Written by Jinfiniti Science on September 24, 2024. Posted in NAD+, NAD, NAD+ Precursors, Popular.

Imagine unlocking boundless energy, razor-sharp focus, and a renewed sense of vitality—not through another fad diet or grueling workout, but by tapping into your body’s own cellular powerhouse.

This isn’t science fiction; it’s the promise of NAD IV therapy, a cutting-edge treatment that’s captivating health enthusiasts and Hollywood A-listers alike.

But as with any breakthrough, the question on everyone’s mind is: Does the price tag match the potential? Read on to discover all you need to know about the costs of NAD therapy and determine whether this cellular rejuvenation is truly worth your investment.

In this article, we discuss:

The science of NAD therapy and understand how it works to boost your energy and vitality.
What you should expect to pay for NAD IV treatment and discover if it’s the right choice for you.
How to enjoy celebrity-level energy and anti-aging benefits without the Hollywood price tag – all for just a fraction of the cost!

NAD IV therapy has quickly become the latest wellness trend, touted for its ability to boost energy, sharpen the mind, and even slow down the aging process.

Hollywood stars like Jennifer Aniston and Justin Bieber use this treatment to optimize their health. Podcaster Joe Rogan is also a fan, adding to the therapy’s growing appeal.

High-performing athletes are getting on board too, recognizing NAD+ IV therapy for its potential to enhance athletic performance and support recovery. In fact, former NFL quarterback Jay Cutler turned to NAD+ therapy after his 12-year career, where he suffered from 15 head injuries.

But before you jump on the bandwagon, it’s important to get a clear picture of the costs involved in ongoing NAD treatment and weigh them against the potential benefits.

What is NAD IV Therapy?

NAD IV therapy is a treatment designed to deliver a powerful coenzyme called nicotinamide adenine dinucleotide (NAD) directly into your bloodstream.

NAD is crucial for cellular energy, aiding in metabolic processes like DNA repair, combating oxidative stress, and regulating circadian rhythms.¹

A 2022 study published in the Frontiers in Endocrinology Journal reported that as you age, your NAD levels naturally decline.² This decline can contribute to various health issues like fatigue and cognitive problems.

The purpose of NAD IV therapy is to replenish these diminishing NAD+ levels quickly and efficiently.

NAD boosts your cells’ energy by enhancing the production of adenosine triphosphate (ATP), the primary fuel that powers cellular function. It also activates a family of proteins called sirtuins, which help repair cellular damage, manage stress, and keep your metabolism in check.³

NAD IV therapy skips the digestive system, sending a concentrated dose of NAD straight into your bloodstream. This can lead to faster and more noticeable benefits. This is why many people report feeling more energized, mentally sharp, and physically resilient after undergoing NAD IV therapy.

How Much Does NAD IV Therapy Cost?

The cost of NAD IV therapy can vary widely, but on average, you can expect to pay anywhere from $500 to $2,000 per session. The exact price depends on several factors, including the clinic’s location and reputation.

In major cities like New York, Los Angeles, and Chicago, a single NAD IV session might range from $600 to $1,000 or more. These cities have a higher cost of living, and clinics often charge a premium for their services to cover expenses and cater to a wealthier clientele.

In contrast, smaller towns or rural areas offer more affordable options, ranging from $300 to $500. Lower costs in these areas often stem from reduced overhead, lower demand, and the need to attract customers with less disposable income compared to big cities.

Moreover, a clinic known for delivering high-quality results or one favored by celebrities and influencers may charge a premium for their services. These clinics often invest in state-of-the-art equipment, highly trained staff, and luxurious amenities, all of which contribute to higher costs.

The cost of NAD IV therapy is also influenced by the dosage and length of each session. Typically, higher doses of NAD+ require more time to administer, resulting in longer sessions and higher costs.

Additional Fees

Beyond the base cost, there are often additional fees to consider.

Many clinics charge for initial consultations, which can range from $100 to $200, depending on the provider. Follow-up consultations may also come with a fee, especially if your therapy is personalized and requires ongoing monitoring.

You may also face costs for add-ons like vitamin infusions or hydration boosters, which can enhance your therapy and address specific health needs. These extras can add another $50 to $200 per session.

If you’re traveling to a clinic far from home, you’ll need to factor in potential travel expenses. This might include transportation, accommodation, and meals, all of which can increase the overall cost of your treatment.

Cost of Multiple NAD Therapy Sessions

NAD IV therapy is often most effective when done over multiple sessions, especially for long-term benefits. As a result, the cumulative cost can add up quickly.

Typically, it’s suggested to start NAD+ IV therapy with weekly sessions for the first four weeks, followed by bi-weekly treatments for the next month. After that, you can often switch to just once a month to maintain the benefits.

If you’re considering a series of treatments, some clinics offer packages or discounts for multiple sessions. However, even with discounts, you might be looking at a total cost of several thousand dollars, particularly if you undergo therapy over several weeks or months.

Is NAD IV Therapy Covered by Insurance?

NAD IV treatment plans are not typically not covered by health insurance in the United States. Most insurance providers consider this treatment elective or alternative, placing it outside the scope of standard medical coverage.

The reason for this lack of coverage is twofold: NAD IV drip therapy is not FDA-approved for treating specific medical conditions and it’s often categorized as a wellness or anti-aging treatment rather than a medical necessity.

While insurance coverage for NAD IV therapy is unlikely, it’s always worth checking with your specific insurance provider. In rare cases, coverage may be possible if the treatment is deemed medically necessary for a diagnosed condition. However, such instances are the exception rather than the rule.

NAD IV Therapy vs Oral NAD Supplement Cost

If you’re aiming to boost your NAD+ levels, two popular choices are NAD IV therapy and oral NAD supplements.

NAD IV therapy is the pricier option, with monthly sessions adding up to around $6,000 a year.

In contrast, oral NAD supplements offer a practical choice, with a month’s supply ranging from $40 to $100. Over a year, you could spend as little as $480, making it a more sustainable way to support your NAD+ levels long-term.

But beyond the price, it’s far more important to consider how these methods work with your body. One key issue with NAD IV therapy is whether the NAD+ actually gets into your cells to boost your levels effectively.

NAD molecules are too big to pass through cell membranes, so most of the NAD+ ends up staying outside the cells. This means NAD IV therapy might not be as effective at raising intracellular NAD+ levels and providing the health benefits you’re looking for.

On the other hand, oral NAD supplements supply your body with the raw materials it needs to make NAD+ on its own. It’s a more efficient approach that directly supports the cellular processes that keep you energized, healthy, and resilient.

Is the Cost of NAD IV Therapy Worth It?

NAD IV therapy can be effective, but there’s a lot to consider.

Each session may take up to 4 hours, so you’ll need to set aside a big chunk of your time. Plus, since multiple sessions are often required, the time and effort can really add up. The speed of the infusion matters, too, as faster infusions are linked to side effects like stomach pain.

If you want to save on both cost and time, oral NAD supplements are a solid alternative.

You can take them whenever and wherever you want—no appointments or long waits.

They come in different forms like NAD powders and sublingual drops, so you can easily fit them into your daily routine.

However, not all NAD supplements are created equal.

Just like with NAD IV therapy, some supplements only contain NAD+ itself, which doesn’t always get into your cells effectively due to its limited bioavailability.

For best results, choose supplements with NAD+ precursors. They’re easier for your body to absorb and convert into NAD+ inside your cells.

SHOP NAD+ SOLUTIONS

Referenced Sources

True Story: Dementia-Related Memory Loss Restored 50% OVERNIGHT

Written by Jinfiniti Science on September 2, 2024. Posted in NAD+, Memory Loss and Brain Fog, NAD, Neurological Diseases, Popular. No Comments on True Story: Dementia-Related Memory Loss Restored 50% OVERNIGHT

Dementia is a serious condition that affects over 55 million people worldwide, with nearly 10 million new cases each year¹.

The impact of dementia goes far beyond the person who is diagnosed; it also deeply affects their families, who struggle with the emotional and mental pain of seeing their loved ones’ memories fade away.

Watching someone you care about lose the ability to do everyday things, forget important moments, or fail to recognize familiar faces can be incredibly hard.

Families often feel helpless and overwhelmed, desperately searching for ways to restore what has been lost.

But there is hope.

Take Marshall, a 94-year-old who completely forgot how to use his phone and computer after being diagnosed with dementia.

After just one night of using Vitality NAD+ Booster, a supplement that contains nicotinamide adenine dinucleotide (NAD) precursors, Marshall’s memory began to improve, and he started to feel more like himself again.

SHOP NAD+ BOOSTER

His story shows that it’s possible to regain lost memories and improve mental clarity.

We hope that you or your loved ones can also benefit from optimizing your NAD+ levels.

Read Marshall’s story below.

I’m not sure what I expected, but…

I was surprised when my dear friend’s cognition declined dramatically overnight at age 94.

Sure, there had been some memory lapses over the course of his 93^rd year.

He occasionally forgot his house keys when he went out. He didn’t always remember everything he had driven to the grocery store to buy. (Yes, he was still driving safely at age 92 and beyond.)

Those lapses were the kind that everyone I know over the age of 40 has complained about, myself included.

Still, the signs of Marshall’s cognitive decline did not progress over the course of weeks or months, as I had believed they would, were they to happen at all.

I had hoped that he was past some imaginary statistical cutoff date by which I had presumed dementia would happen. I had read somewhere that by the age of 80, 1 in 6 people experienced some degree of dementia.

When my dear friend reached and passed his 90^th birthday with a mind sharp as a tack I assumed he was all clear.

By the time he celebrated his 94^th birthday, I relished the fact that he remembered things better than many 40-year-olds and he still “figured stuff out” (his phrase) really well for a person of any age.

Give him a problem to solve and if he hadn’t done so by day’s end, he would always spring out of bed the next day declaring, “I’ve got it!” having solved the problem throughout the night.

Marshall’s great mind and good memory were perfectly intact until one fateful day.

That day I discovered him sitting on his bed staring quizzically at his phone.

I asked him, “What are you doing, M?” He looked at me, bewildered, and replied, “I don’t know.”

I pressed him further. “What do you mean, ‘You don’t know’? Are you trying to call someone on your phone?” I asked.

“I’m trying to figure that out,” he told me. “I’m working on it.”

His words weren’t making sense to me. Working on what? What did he mean?

“Marshall,” I began, worried, “What do you mean ‘working on it”? What’s to work on? Just make the call if that’s what you’re trying to do.”

He looked at me with a blank expression and replied, “I don’t know how.”

I flashed back to years earlier when a very beloved actor friend of mine had called me at my apartment in New York City. He was talking to me in disconnected, somewhat incoherent phrases that I couldn’t understand.

Clearly, something was wrong.

I asked him where he was and he somehow managed to tell me with words that made some sense that he was at the nearby Apple Store.

I told him to stay where he was, that I would be right over. I quickly threw on a jacket and ran the four blocks to the store.

I found my friend sitting at a display bench downstairs in the store with an Apple clerk who seemed concerned.

My friend was insisting that she sell him a new iPhone, which she explained to me she didn’t want to do because his current model phone was working just fine.

I told her to cancel the order, which she didn’t want to place anyway.

I asked him a few questions, which he answered only somewhat coherently.

I apologized to the salesgirl and walked my friend out of the store. I found a bench where he could sit comfortably while I called his family at their home.

They were understandably concerned when I told them about his condition.

They were in another state but together we made the decision that I should get him to the nearest Urgent Care.

The staff there quickly diagnosed a suspected stroke and, with their help, I hastily got my friend to a nearby hospital.

He spent a week in the hospital and recovered, but things could have gone in a whole other direction had I not jumped into action when I did.

Was Marshall suffering the effects of a stroke? I determined to keep a close eye on him throughout that entire day.

I observed him sitting and staring into space from time to time, as though lost in thought.

When I asked him what he was thinking about, he said, “I’m figuring something out,” and he would return to gazing off into the distance with a vacant stare.

Later that day I discovered him sitting at his computer, staring at the screen, immobile.

“What are you doing, Marshall?” I asked him.

“I don’t know. I can’t answer that,” he said, clearly frustrated and confounded.

From one day to the next my friend had forgotten how to use both his cellphone and his computer.

Worse, he seemed “not all there” mentally.

There’s more but I won’t go into the details, which included some bathroom and basic walking issues. Suffice it to say he had devolved significantly over just 24 hours.

Over the next weeks, I took my friend from doctor to specialist to lab to ascertain exactly what was going on.

A brain MRI (not fun for him at all) ruled out any suspected brain mass/tumor but…

A battery of cognitive tests with a gerontology professional confirmed that he was experiencing mild to moderate dementia.

Watching him take that cognition test was painful because questions that he would have aced just the week before gave him great difficulty in answering.

He couldn’t even begin to draw the clock face requested in the test.

A former whiz with numbers, he was stumped when asked to count back from 100 in 7’s. (100, 93, 86, etc.) His frustration turned to anger and eventually, he refused to participate in completing the test.

Once home, I was shocked to discover that Marshall had completely mixed up his daily meds.

As a forever health freak and gym rat, he had always been compliant and rigorous with taking vitamins and the few prescriptions he was on.

He had gone on his first prescription meds just a few years before when diagnosed with non-small-cell lung cancer.

He was doing ok with that disease, given his age and the severity of such a condition.

The health equity he had built up over decades of clean, healthy living stood him in good stead to do battle with cancer.

He never missed a prescribed dose of anything the oncologist ordered and his vitamin game was strong after years of taking a full regimen of fitness and bodybuilder supplements.

However, a review of his medicine cabinet that day showed that things had gone very awry.

Some bottles that I knew should be there were missing and others contained far too many pills than they should have since the date of fulfillment at the pharmacy.

When I asked him if he had been taking his pills regularly, as he had always done, he looked at me with that new vacant, uncomprehending stare.

I took possession of all bottles from his bathroom shelf and called all of his prescribing doctors to review his treatment plan and get him back on track.

I took over the administration of meds and supplements. I felt lucky to have discovered the issue when I did.

Fortunately, doing some math on the bottles and the number of pills inside them proved that the pill problem had occurred concurrently with the cellphone and computer problem. Suddenly and recently.

With a heavy heart, I booked tours of Assisted Living homes in advance of what I was sure would soon be the need for 24/7 memory care.

And then I had a thought.

What if Vitality NAD+ Booster, a NAD supplement formula and known neurotransmitter, could help?

It is a favorite of mine and so many others for energy mental clarity and more. Why not give it a try?

That night I gave Marshall his first dose of the clinically-proven powder. The next morning? Nothing short of a medical miracle.

I could kick myself for not having recorded the “before” Vitality NAD+ Booster Marshall to the man who woke up that next day.

When I claim a 50% improvement in his cognition OVERNIGHT it sounds preposterous even to me!

Except I witnessed it. I continue to see it daily.

Has he suddenly regained 100% of his memory and ability to solve problems and think clearly?

Most definitely not. He is, however…

At least 50-65% cognitively recovered.

He knows how to use his phone, he’s back at the computer, those bathroom issues are pretty much gone, and he’s using his walker and cane as well as he formerly had.

He is now back in charge of his meds and supplements because he began to remind me to give him doses as he remembered what to take and when.

I check daily to make sure he has not forgotten anything, of course, but so far, so good.

I do mix up his Vitality NAD+ Booster for him and give him two scoops daily.

When he sees me coming with it, his eyes light up and he says, “Dr. She’s stuff?” and I shake my head “yes” in acknowledgment.

I think he looks forward to it because he knows the good it does him.

During a doctor visit with his Primary Care Physician yesterday, the doctor acknowledged the improvement he saw in Marshall.

I told him what I had added to the program and he said, “Well great, there is good data on that supplement.”

He’s one of the physicians I had taken Marshall to see to evaluate the sudden mental decline.

He’s the same doctor who had told me back then several months ago that Marshall could not be left alone anymore.

“If he can’t use his phone and he gets in trouble, it’s a big problem,” he advised.

Plus, he mentioned the stove incident that had happened during that awful week:

Marshall had turned on a gas burner that didn’t light and some gas fumes escaped before I noticed what was happening.

I’m grateful for however many months, hopefully, even years, that this product will enable my dear friend to enjoy his mind and his memory.

If it stopped working tomorrow, I would still be grateful today for the past six weeks of improvement.

Dementia moves in and makes itself at home with all too many families today. It’s a significant global health challenge.

Here are some key statistics highlighting the fact that it’s not “if” it’s “when” a friend, neighbor, work colleague, or family member of yours may experience this heartbreaking condition:

Global Prevalence: As of 2023, more than 55 million people worldwide are living with dementia. This number is expected to nearly triple by 2050, reaching 139 million due to aging populations.

Incidence: Around 10 million new cases of dementia are diagnosed each year. That equates to one new case every 3 seconds.

Age Factor: Dementia primarily affects older adults. About 1 in 6 people over the age of 80 have dementia. However, early-onset dementia, which occurs before the age of 65, accounts for about 9% of cases.

Economic Impact: The global cost of dementia is estimated to be over $1 trillion annually, including healthcare costs, informal care, and loss of productivity. This figure is projected to increase significantly in the coming decades.
Mortality: Dementia is one of the leading causes of death worldwide. In many countries, it ranks as the second or third leading cause of death among older adults.

Gender Disparity: Women are disproportionately affected by dementia. Approximately two-thirds of people with dementia are women, partly because women tend to live longer than men.

Alzheimer’s Disease: Alzheimer’s disease is the most common form of dementia, accounting for 60-70% of all cases.

These statistics underscore the importance of research, prevention, and support for those affected by dementia.

For those dealing with this problem, knowing that there’s a supplement that might, just might, mitigate some of the memory loss, should be welcome news.

In my opinion, Vitality NAD+ Booster is worth a try.

SHOP NAD+ BOOSTER

Referenced Sources:

https://www.who.int/news-room/fact-sheets/detail/dementia ↩︎

NAD IV Therapy: How Often Should You Get It?

Written by Jinfiniti Science on August 28, 2024. Posted in NAD+, NAD. No Comments on NAD IV Therapy: How Often Should You Get It?

If you’ve already tried NAD IV therapy or are thinking about it, how do you know if it’s truly working for you?

If you’re not seeing the energy boost or vitality you hoped for, you might not be getting enough NAD from your current routine.

Read on to find out how NAD IV therapy works, why the frequency of your sessions matters, and whether it’s truly the right choice for you to achieve lasting energy and vitality.

In this article, we discuss:

How NAD IV therapy affects your body and whether your current routine is enough to keep you energized
How the right frequency can make or break your results
A simple yet more effective alternative to frequent NAD sessions that delivers long-lasting benefits at the cellular level

You’ve heard the buzz about NAD IV therapy and its powerful benefits—more energy, sharper focus, and a youthful glow.

But here’s the million-dollar question: How often should you get it to truly reap its benefits?

Too little, and you might not feel the full impact; too much, and you could be overdoing it.

The right frequency can boost your energy levels and support long-term vitality, helping you feel more focused and thriving daily.

What is NAD IV Therapy?

NAD IV therapy is a rejuvenating treatment that delivers a concentrated dose of nicotinamide adenine dinucleotide (NAD) into your bloodstream.

It’s a top pick for those who want to raise their NAD levels quickly, such as in cases of severe NAD depletion or chronic fatigue.

Low NAD levels can speed up cellular aging and mess with your energy production and DNA repair¹.

In NAD IV therapy, a sterile saline solution with NAD is slowly infused into your vein.

This method ensures that NAD is delivered directly to your cells without delaying absorption through the digestive system for more immediate results.

NAD IV therapy is known to boost energy levels, making you feel more vibrant and alive.

It also helps fight aging, promoting healthier skin, reducing wrinkles, and even improving sleep.

Beyond that, NAD IV therapy can enhance cognitive function, improve memory, and increase mental clarity.

Factors That Influence the Frequency of NAD IV Therapy

Everyone is different, so how often you should get NAD IV treatments can vary based on a few key factors, including…

Individual Health Goals

Your health goals play a major role in determining how often you should undergo NAD IV therapy.

Whether you’re targeting aging, boosting brain power, or recovering from a condition, you’ll need a different session frequency.

If you’re using NAD IV therapy mainly for anti-aging, you might need fewer treatments than someone using it for cognitive enhancement.

A personalized treatment plan that aligns with your specific goals is essential for getting the best results.

Current NAD Levels

Your baseline NAD levels are another crucial factor in determining how often you should receive therapy.

If your NAD levels are already low, you might need more frequent sessions to build them back up.

Conversely, if your levels are relatively high, less frequent treatments might be sufficient.

To get an accurate picture of where you stand, you can take an Intracellular NAD Test.

This test measures your NAD levels, helping you and your healthcare provider create a treatment plan that’s just right for you.

TEST YOUR NAD LEVELS TODAY

Age and Lifestyle Factors

As we age, our NAD levels naturally decline, making more frequent treatments beneficial.

Older adults may need more frequent NAD treatments² to restore and maintain optimal levels, while younger people might only need treatments every few months.

Additionally, factors like diet, stress levels, and lifestyle habits, such as exercise or lack thereof—can accelerate NAD depletion.

If your lifestyle is particularly demanding or your diet isn’t as balanced as it could be, you might need NAD IV therapy more often.

Overall Health and Medical Conditions

Your overall health and any underlying medical conditions also matter in deciding how often you should receive NAD IV therapy.

Chronic illnesses or certain health conditions may require more frequent treatments to see effective results.

For instance, those with neurodegenerative diseases might benefit from more regular NAD infusions³ over a more extended period to help manage their symptoms and improve their quality of life.

Your healthcare provider can help you determine the best approach based on your unique health needs.

Recommended Frequency for Different Goals

To hit your specific health goals, here’s a quick guide to the recommended NAD IV therapy frequency for different needs:

For General Wellness and Anti-Aging

If you’re looking to maintain overall health and slow the aging process, NAD IV therapy can be a powerful tool.

You might begin with three infusions every other week⁴, then move to a monthly maintenance session.

For the best results, many start with 1-2 sessions per week for the first 4-6 weeks⁵.

After that, a maintenance schedule of sessions every 4-6 weeks is usually recommended to keep NAD levels stable, supporting cellular repair and energy production.

For Cognitive Enhancement and Mental Clarity

The brain demands a lot of energy to function at its best.

If you’re looking to enhance cognitive performance or prevent decline, starting with a more frequent schedule, such as once or twice a week⁶ for the first month, is often recommended.

This can rapidly increase NAD levels in your brain, leading to better focus and memory.

After this initial period, you can reduce the frequency to one session every two to four weeks to keep your mind sharp.

For Athletic Performance and Recovery

Athletes and individuals who engage in intense physical activity can benefit from NAD IV therapy to enhance endurance and speed up recovery.

You might only need a few sessions throughout your training⁷ and then another right before big events like a marathon.

Once you’ve built up your NAD levels, you might reduce the frequency to once a month, maintaining peak performance and recovery.

NAD therapy aids in muscle recovery and reduces fatigue, helping you perform at your best.

For Chronic Conditions or Severe NAD Depletion

If you’re dealing with a chronic illness or have significant NAD depletion, more frequent NAD IV therapy sessions may be necessary.

In these cases, starting with two to three sessions per week⁸ can provide the needed boost to your NAD levels, helping manage symptoms and support overall recovery.

As your condition improves, you may gradually reduce the frequency of treatments.

However, maintaining regular sessions, such as once a week or bi-weekly, can be crucial for long-term management of chronic conditions.

NAD IV Therapy vs Oral NAD Supplement: Which Works Best?

When boosting your NAD levels, both NAD IV therapy and oral supplements can get the job done—but which one is right for you?

If you’re looking for a quick, powerful boost—perhaps to address more severe symptoms—NAD IV therapy might be the way to go.

However, it’s not without its drawbacks.

Because the NAD+ molecules are too large to pass through cell membranes on their own, this method primarily benefits the bloodstream, only offering a rapid boost.

However, a study published by Frontiers in Aging Neuroscience found that NAD levels in the blood plasma didn’t increase until a few hours into the infusion.

Initially, NAD broke down in the first two hours, so it had little effect on blood levels⁹.

Plus, NAD IV therapy can be expensive—around $200 per session—and if your treatment plan calls for multiple sessions a week, the costs can add up quickly.

On the flip side, oral NAD supplements offer a more gradual and cost-effective approach.

These supplements usually have NAD precursors, such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), which your body converts into NAD+.

While they might not give you the quick burst of energy that IV therapy can, they’re very effective for delivering benefits directly at the cellular level.

Over time, these supplements support sustained energy, better metabolism, and overall health from within.

They’re also easier on the wallet and more convenient for daily use.

TEST YOUR NAD LEVELS TODAY

Referenced Sources:

What is NAD IV Therapy and Should You Consider It?

Written by Jinfiniti Science on August 26, 2024. Posted in NAD, NAD+, Popular. No Comments on What is NAD IV Therapy and Should You Consider It?

In upscale wellness clinics and medical spas across America’s affluent neighborhoods, a new kind of intravenous treatment has gained prominence among those seeking the latest in regenerative medicine. NAD IV therapy – or intravenous NAD therapy – represents a growing trend in the world of alternative wellness treatments, where patients receive the vital cellular compound Nicotinamide Adenine Dinucleotide (or NAD) through direct intravenous administration.

NAD is a coenzyme found naturally in every cell of the human body, playing a key role in cellular function and energy production. Often called a “helper molecule,” it assists in hundreds of metabolic processes, particularly in converting food into cellular energy and maintaining healthy DNA.

In this article, we’ll cover:

What NAD IV therapy is and how it works to deliver NAD+ directly into the bloodstream
The potential benefits of NAD IV therapy, from addiction recovery and cognitive enhancement to anti-aging and cellular health optimization
The safety considerations, side effects, and costs associated with NAD IV infusions
How NAD IV therapy compares to oral NAD supplements in terms of efficacy, convenience, and scientific support

What is NAD IV Therapy?

NAD IV therapy, sometimes referred to as NAD infusion or IV drip, typically takes place in medical clinics or specialized wellness centers, where patients recline in comfortable chairs for sessions lasting anywhere from two to four hours. A healthcare provider inserts an IV line into the patient’s arm, connecting them to a drip containing a solution of NAD+ (the oxidized form of NAD) mixed with saline.

The lengthy duration of the treatment isn’t due to the volume of fluid – rather, it’s intentionally slowed to minimize the side effects that can occur with rapid administration. Some clinics offer private rooms equipped with entertainment systems and other amenities to help pass the time.

What began as a niche treatment in high-end coastal clinics has expanded into a nationwide phenomenon. Prices typically range from several hundred to over a thousand dollars per session, with many practitioners recommending initial protocols of 4-10 treatments followed by periodic maintenance sessions.

Medical spas, integrative medicine clinics, and even traditional medical practices have begun offering NAD IV therapy. NAD treatment has found particular popularity in wealthy enclaves from Beverly Hills to the Hamptons, where it joins a growing menu of wellness interventions aimed at an affluent clientele.

The therapy exists in a regulatory gray area – while the administration of IV treatments requires medical supervision, the NAD compounds themselves are typically obtained through compounding pharmacies. Practitioners range from medical doctors to naturopathic physicians, depending on state regulations regarding IV therapy administration.

Unlike traditional medical treatments, NAD IV therapy often operates in the cash-pay market, outside the usual insurance frameworks. This has contributed to its reputation as a luxury wellness service rather than a conventional medical treatment.

In clinics across the country, practitioners present this therapy as part of a broader approach to cellular health and regeneration, positioning it alongside other emerging treatments in the rapidly expanding field of longevity medicine.

Takeaway: NAD IV therapy is a lengthy (2-4 hour) intravenous treatment administered in medical clinics and wellness centers, where NAD+ mixed with saline is slowly dripped into patients to minimize side effects.

Does NAD IV Really Work to Increase NAD+ Levels?

When discussing treatments to increase NAD+, it’s important to understand the distinction between intracellular (iNAD+) and extracellular (eNAD+) forms, since they have dramatically different concentrations and roles.

Intracellularly, NAD+ is abundant, typically ranging from micromolar to millimolar concentrations¹. In contrast, extracellular NAD+ levels are remarkably low, measuring approximately 500 times less concentrated than intracellular levels².

When NAD is administered intravenously, it primarily affects extracellular NAD+ levels. Research demonstrates that IV NAD+ infusion has minimal direct impact on intracellular NAD+ concentrations. In fact, studies show that during a continuous NAD+ infusion, plasma levels only significantly increased at the 6-hour mark, with a 398% rise relative to baseline³.

The body does not directly incorporate IV NAD+ into cellular NAD+ pools. Instead, metabolites like nicotinamide (NAM), nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN) can potentially enter cells and be used to regenerate NAD+⁴.

Recent research indicates that IV NAD+ may not significantly elevate whole blood NAD+ levels within 24 hours, suggesting limited cellular penetration and utilization⁵. This underscores the complexity of directly increasing cellular NAD+ through IV administration.

Moreover, our own research at Jinfiniti has found that NAD IV therapy does not significantly increase NAD levels inside the cells for several reasons.

First, the amount of infused NAD+ and the frequency of infusions do not provide sufficient NAD+.
Second, NAD+ is rapidly degraded in the bloodstream within hours.
Third, the NAD+ molecule is too large to penetrate the cells.

Take a look at the graph below.

The use of 750 mg of intravenous NAD+ infusion over 5 sessions did not increase intracellular NAD levels (indicated by the blue bars in the chart).

Meanwhile, oral NAD supplementation for four weeks optimized NAD levels in 7 of 8 test subjects and significantly boosted NAD in others (indicated by the green bars in the chart).ur weeks optimized NAD levels in 7 of 8 test subjects and significantly boosted NAD in others (green bars).

This suggests that NAD+ infusions may not be an ideal option for those looking to increase energy, improve performance, or extend longevity.

Takeaway: IV NAD+ therapy primarily affects extracellular NAD+ levels but has minimal direct impact on intracellular NAD+ concentrations.

Potential Benefits of NAD Therapy

While the jury is still out in the scientific community on the full scope of NAD IV therapy’s effectiveness, proponents of this treatment cite a range of potential benefits that have attracted a dedicated following among wellness enthusiasts and those seeking alternative approaches to health optimization. These benefits are mostly attributable to an increase in NAD+ levels, which, as mentioned above, is more nuanced than some may think.

Addiction Recovery

Clinical studies on NAD+ IV therapy for addiction remain limited, but one review indicates potential as an anti-addiction intervention by addressing multiple neurobiological aspects of addiction. Previous clinical reports have documented benefits of IV NAD+ infusion in alcohol and opioid withdrawal, with researchers observing significant improvements in reducing cravings and alleviating withdrawal symptoms⁶.

Energy and Metabolism

Practitioners report that many patients seek out NAD therapy primarily for its effects on energy levels. The treatment’s supporters point to NAD’s fundamental role in cellular energy production⁷, likening it to recharging a battery at the cellular level. Some clinics report that patients experience increased energy levels lasting days or even weeks following treatment.

Cognitive Function

In Silicon Valley boardrooms and Wall Street offices, executives have turned to NAD therapy in pursuit of supercharged mental clarity. Advocates suggest that the treatment may support brain function by helping maintain healthy neurons and potentially reducing inflammation⁸. Some patients report experiencing improved focus and mental acuity, though these effects remain largely anecdotal.

Athletic Recovery

Professional athletes and fitness enthusiasts have embraced NAD therapy as part of their recovery protocols. The treatment’s proposed ability to support cellular repair and energy production has made it popular among those seeking to optimize their physical performance and reduce recovery time between intense training sessions.

Age-Related Concerns

Perhaps the most intriguing area of interest lies in NAD’s role in aging. Research has shown that NAD levels naturally decline with age⁹, leading some scientists to investigate whether restoring these levels might influence the aging process. The potential anti-aging effects of NAD IV have certainly captured the attention of the longevity medicine community and warrant further exploration.

Cellular Health

Proponents believe that NAD IV therapy may help support overall cellular health by improving mitochondrial function – the energy-producing centers within cells. This could potentially have wide-ranging effects on various aspects of health, from metabolism to tissue repair.

Metabolic Function

Clinics report that some patients seek NAD therapy for its potential to support healthy metabolism. The treatment’s role in cellular energy production has led to speculation about its effects on metabolic health, though research in this area continues to evolve.

How Safe is NAD IV Treatment?

While many practitioners consider the treatment generally safe when administered properly, patients should be aware of various side effects and safety considerations before pursuing IV infusion.

During IV NAD therapy sessions, patients frequently report a range of temporary symptoms that typically subside once the infusion is complete or shortly thereafter:

Chest tightness or discomfort
Moderate to severe headache
Shortness of breath
Nausea and stomach discomfort
Flushing of the face
Racing heart or palpitations
Anxiety or jitteriness
Mild dizziness
Temporary changes in vision

The speed of NAD administration plays a significant role in the intensity of side effects. Experienced practitioners typically begin with lower doses and slower infusion rates, gradually increasing them based on patient tolerance. This approach, while extending treatment duration, helps minimize adverse reactions.

NAD IV therapy has been observed to elevate high-sensitivity C-reactive protein (hs-CRP) levels, with approximately 70% of recipients showing a 3- to 10-fold increase in this inflammation marker. Given these effects, monitoring hs-CRP and implementing inflammation control measures is recommended for patient safety.

Medical professionals stress that NAD IV therapy should only be administered in appropriate clinical settings with proper medical supervision. The treatment requires careful screening of patients for underlying health conditions that might contraindicate its use.

Certain populations may face higher risks when receiving NAD therapy. People with kidney or liver conditions, heart problems, or those taking specific medications should exercise particular caution. Pregnant or nursing women are typically advised to avoid the treatment due to limited safety data.

The medical community notes that while short-term side effects are well-documented, the long-term safety profile of regular NAD IV therapy remains under investigation. Some healthcare providers express concern about the lack of extensive longitudinal studies examining the effects of repeated treatments.

The rapidly growing NAD therapy industry has raised concerns about quality control and standardization. The source and purity of NAD compounds can vary between facilities, potentially affecting both safety and efficacy. Patients are advised to thoroughly research facilities and verify the credentials of practitioners administering the treatment.

Takeaway: NAD IV therapy can cause temporary side effects like headaches and nausea, with severity depending on infusion speed and individual tolerance. While generally considered safe under proper medical supervision, certain populations face higher risks, and long-term effects remain under study.

How Much Does NAD IV Therapy Cost?

NAD IV therapy costs can vary widely based on dosage, location, clinic expertise, and additional treatments. On average, the cost ranges from $200 to $1,000 per session. For longer-term treatment plans, costs can accumulate significantly. Many providers recommend multiple sessions over several days or weeks for optimal results, which can drive up the total expense. For example, a series of treatments over 2-3 days could cost $1,500 to $3,000 or more.

Some clinics offer package deals or membership options for regular treatments, which may provide some cost savings for ongoing therapy. It’s also important to note that NAD IV therapy is generally not covered by insurance, as it’s considered an elective treatment.

Is NAD IV FDA-Approved?

NAD IV therapy is not FDA-approved for the treatment of any specific condition. This does not mean the treatment is illegal or unsafe when administered properly. NAD therapy falls under the category of dietary supplements, which are not required to undergo FDA review for safety or effectiveness before being marketed. The FDA has acknowledged NAD therapy’s potential efficacy for treating certain conditions like benzodiazepine dependence, opiate withdrawal, and chronic fatigue, though it has not formally approved it.

NAD Infusions vs Oral NAD Supplements

NAD supplementation offers two primary approaches: oral NAD supplements and IV therapy, each with distinct advantages for individuals seeking to boost cellular energy and combat aging. Oral supplements provide a convenient, cost-effective method for gradually increasing NAD+ levels, with studies showing potential increases up to 142% after two weeks of consistent use¹⁰. These supplements are typically more affordable, ranging from $20 to $150 per bottle, and can be easily integrated into daily routines.

In contrast, intravenous therapy delivers a rapid, direct NAD+ boost directly into the bloodstream, making it potentially more suitable for acute health conditions or intensive recovery needs. However, this method comes with significant drawbacks, including the higher costs and potential side effects outlined above.

It’s worth noting that the majority of peer-reviewed studies have focused on oral NAD+ supplements rather than intravenous delivery. This research disparity stems from several practical factors. Oral supplement studies offer advantages in scientific settings: they’re easier to control, more cost-effective to conduct, and more practical for the large-scale, long-term trials needed to establish clinical efficacy. Major research institutions have primarily concentrated their investigations on oral NAD+ precursors such as NMN and NR.

Many of the benefits attributed to IV NAD+ therapy are extrapolated from studies on oral supplements, which often have different bioavailability and physiological effects. This disconnect has led some researchers to call for more rigorous investigation of the IV delivery method, particularly given its growing popularity and higher cost compared to oral alternatives.

Takeaway: Oral supplements are backed by more extensive research and clinical trials, while IV therapy’s effects are less thoroughly studied despite its growing popularity.

Should You Get NAD IV Therapy?

When considering IV therapy, it’s important to carefully weigh the potential NAD+ benefits against the risks, costs, and limitations. While many individuals report positive experiences with this treatment, the scientific evidence supporting its efficacy remains limited compared to well-studied oral NAD supplements.

The allure of a rapid NAD boost via IV infusion is understandable, particularly for those facing acute health challenges or seeking accelerated recovery. However, the higher costs, potential side effects, and lack of long-term safety data should give pause to anyone considering this approach.

In contrast, oral NAD supplements offer a more accessible, affordable, and scientifically validated option for gradually increasing NAD levels over time. With a growing body of research supporting their safety and efficacy, these supplements may represent a more prudent choice for the majority of individuals seeking the benefits of NAD therapy.

Ultimately, the decision to pursue NAD IV therapy should be made in close consultation with a trusted healthcare provider who can assess your individual needs and risk factors. They can help you evaluate whether the potential benefits outweigh the risks in your specific case, and guide you toward the most appropriate options for supporting your health and well-being.

For those interested in a clinically proven, convenient, and cost-effective alternative to IV therapy, Jinfiniti’s Vitality ↑® NAD+ Booster stands out as a compelling option. This patent-pending oral supplement combines four powerful ingredients – NMN, creatine monohydrate, D-ribose, and nicotinamide – to optimize NAD levels through multiple pathways.

Vitality’s unique formulation includes both a one-step NAD precursor and supports the salvage pathway that recycles nicotinamide, while creatine monohydrate serves as an ATP energy reservoir and potential neurotransmitter. All ingredients are third-party tested for the highest purity, ensuring a safe and effective way to revitalize cellular function without the risks and costs associated with IV therapy.

DISCOVER NAD+ BOOSTER

Referenced Sources:

How NAD Gave My Dog Six More Months Of Health, Happiness, And Life

Written by Jinfiniti Science on August 20, 2024. Posted in NAD+, Longevity, NAD.

Those of us who choose to lead a healthy lifestyle are keenly aware that diet, exercise, supplementation, quality sleep, and stress management are key components on our path.

Those of us who are pet owners also want our pets to enjoy the same good health and long life that we envision for ourselves.

I’d like to share my Romeo the Red toy poodle’s senior year NAD supplementation story…

… so that others’ dogs may benefit from what I learned as I faced health challenges for Romeo.

There’s a saying that I read months after Romeo passed and it touched me deeply: “A dog might only be there for part of your life, but to them, you are their entire life ”

Wow! That one floored me.

For us, a dog might be one aspect of a busy life filled with work, family, and countless other commitments. But to our dogs, we are everything—their world revolves around us, and their loyalty, love, and devotion are unwavering.

Nowhere is this more evident than every time we return home to an excited, loving greeting from our loyal companion, who has waited patiently for our return.

The jumping, the tail wags, the unbridled excitement that we are “back” is a constant reminder that we are loved and missed, even for short periods of time.

Dogs teach us the true meaning of unconditional love.

They don’t care about our flaws or mistakes; to them, we are perfect. This kind of love is rare, and it’s why the bond we share with our dogs is so special.

They remind us to live in the moment, to appreciate the simple joys of life, and to always greet the people we love with enthusiasm and warmth. In return for their boundless love, we owe them our time, attention, and care—because while they may be just a part of our lives, we are their whole world.

Perhaps the most important role in our dog’s life is that of steward of their health.

We decide what they are going to eat, where they will go, and upon which bed or floor they will sleep. It is on us to make sure their lives are safe, comfy, and secure.

Their very lifespan, for the most part, is in our hands. Ensuring that our pet lives as many years as possible before the Rainbow Bridge crossing becomes a challenge that we take seriously once conditions dictate that we recognize that we will live on but our furbaby will not.

My red toy poodle Romeo finally began, at about age 12, to show his first symptom of aging.

I say “began” because up until that point, people often mistook him for a puppy.

However, this day when he went outdoors for his midday walk, he took a few steps and then just stopped. He began to flinch and jerk backward, reacting to “something.”

I pulled gently on his leash, but he just stood there, his head jerking side to side rapidly, as though he was in pain.

He continued to back away, not proceeding forward, clearly in distress. I assumed he was having some sort of seizure. I’d had a Yorkie named Missy who lived to 17 ½.

In Missy’s last years, she became epileptic and seizures were a common occurrence. This was new for Romeo and scary for both of us.

I picked him up off the pavement and jumped into my car, racing him to the doggie ER nearby.

Those of you who have endured a dog healthcare emergency of any sort know well the anguish, fear, and stress that send your heartbeat racing and cortisol levels soaring.

This event happened during Covid and lockdown measures and my stress was further exacerbated by having to hand my poor, shaking little fluffball off to an attendant for transport to the vet’s exam room.

After what seemed like an eternity, Romeo and I were reunited in the vet’s waiting room.

Once outside and in the car, I received the promised telephone follow-up call from the vet. (Again, this was during Covid and personal contact was limited, if allowed at all.)

I was informed that Romeo’s ailment was not epilepsy and that he had not suffered a seizure. The vet diagnosed the condition as one in his eyes.

His irises were atrophied and the flinching and jerking away movements were from sunlight straining his eyes.

He had become extremely light-sensitive. From that point on, nearly any amount of sunlight would cause him extreme discomfort.

Like many of the symptoms of aging in humans, this new condition had shown up in my dog seemingly overnight. (I remember my vision devolving significantly the night of my 4oth birthday.

I went to bed with 20/20 vision and woke up with presbyopia. At least that’s how it seemed.)

That eye diagnosis marked the beginning of Romeo’s new dog walk program.

I had to walk him in the early morning or late in the day. If I popped out midday to run an errand, I made sure to shield his eyes while driving in the car during daylight. I had suddenly become the official Steward of Senior Dog Health, a mantel I happily assumed.

As with all slippery slopes, Romeo’s aging started slowly but gained speed with time. I began to search in earnest for doggie longevity products and ways to keep him agile and aware.

I was so proud when, even at age 14, people still mistook him for a puppy. I loved the look of shock on their faces when I told them his age.

Still, rainy days were anathema to his joints. Running up and down stairs one day would result in some hobbling and stiffness the next. I tried little grip booties to keep his legs from sliding out from under him on slippery floors. Getting up and down out of his dog bed became a chore.

It was a few months into his 14th year that his arthritis took a heavier toll.

He was achy and listless many mornings when we prepared for his first walk of the day. Clearly, he was experiencing serious joint pain that affected his mobility.

That last year saw Romeo having bladder control issues. Perfectly housebroken for years, he began to have accidents if he wasn’t walked every two hours.

My work and personal life were adjusted to ensure that I, or occasionally someone else, could walk him constantly. Yes, I set my alarm and got up in the middle of the night to walk him as well.

Non-dog people told me things ranging from…

“He’s just a dog, time to let him go” to “You have a life to live, it’s too much.”

But I soldiered on, as did Romeo.

He was a proud boy and having accidents embarrassed him.

His GI tract became problematic and there were bouts of diarrhea that were not fun for either of us. Eventually, his energy level declined to the point that he was sleeping most of the day and worn out or too stiff for the most brief walks.

Halfway into that last year, after an emergency vet visit for extreme diarrhea and total loss of appetite (a confusing combination, to say the least)…

My lovely vet lady pulled me aside and suggested that it might be time to make “the decision.”

I began to cry and she wanted to console me. “Well,” she said, “It might not be today. But it reasonably could be.”

I looked her deeply in the eye and asked her, “How do you know? “

I don’t want to play God.” She answered,

“He’s not eating. He’s in pain. His organs are beginning to fail. “

I had told her what our schedule had become, the every two-hour walks night and day, the constant cleaning up of “problems” and more.

With all that in mind, she said, “The truth is, at some point one of you is going to give up.“

I looked her squarely in the eye, tears streaming down my face, and said, “But today is not that day.”

We went home, little Romeo and I. That night, I had an idea.

I had been taking Vitality ↑® NAD+ Booster for about a year and a half. I knew the benefits I was enjoying. I’d seen it work wonders for friends and family who had issues ranging from allergies to lack of energy to brain fog to inflammation.

I called Dr. Jin-Xiong She and somewhat brusquely asked him, “Why can’t I give my senior dog Romeo Vitality ↑® NAD+ Booster?”

He paused only briefly before answering, “You can!”

That night I sprinkled the NAD precursor powder cocktail Vitality ↑® NAD+ Booster on Romeo’s food.

This is the dog who had turned his nose up at anything I had bought or prepared for him for at least a month.

I purchased high-end gourmet dog foods that cost a fortune.

I put him on a subscription for fresh dog food delivered to the door. I cooked for him more than I did for myself. He would take a sniff, turn away, and slowly walk back to his bed to fall asleep again.

He was skin and bones.

However, that night, after I placed his bowl back on the floor and walked away, something amazing happened.

Romeo did the same sniffing he had been doing for weeks. He poked with his nose and smelled the powder-covered dog food.

He gave a perfunctory lick to the top of the food in the bowl. And then he ate. He ate and he ate.

He finished the bowl.

I’d love to say that he jumped up on his hind feet and did a little doggy jig, but he did not.

He did, however, get back into his bed and fall asleep.

The next morning Romeo once again ate the food with the Vitality ↑® NAD+ Booster added.

When we went for our walk, he had the hint of a spring in his step.

Over the next weeks, he continued to eat and enjoy the food/NAD combo, twice a day, a half doggy dose.

The thing that made me most happy was when, upon returning from a walk, he did what he had not done for months: he raced down the hallway from the elevator in our building to the front door of our condo.

That little run had been one of the cutest things ever for years and it always brought a smile to my face. It was like he was running the Derby and in the last stretch determined to beat the rest of the racers.

He would land in front of our door and turn to me sit back on his haunches and look at me as though to say, “What’s taking you so long, slowpoke?”

I have videos of Romeo making that run again in his last year after months of a slow drag back home.

My little red boy crossed the Rainbow Bridge six months after his vet had suggested it might be time.

Vitality ↑® NAD+ Booster gave him six months of reasonable health, happiness, and life.

I had known that his journey to that Bridge was not far off on the horizon, but it was still a surprise the morning it came.

My friend Sabrina had a cute little girl (Jazzy) like my Romeo, and she had had to let Jazzi cross the bridge a few weeks before Romeo did.

Yet another friend of mine, a bestie from grade school, had arrived home after work a few months before to find that her rescue dog had passed in her absence.

These had both prepared me to some degree, but the last day with a pet is always loaded with shock and sadness.

What comforted me was knowing that the last six months Romeo lived were made possible and were more comfortable thanks to Jinfiniti Precision Medicine’s Vitality ↑® NAD+ Booster.

My next dog will be given his Vitality ↑® NAD+ Booster daily from the moment I bring him/her home.

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Is NAD a Healthy Weight-Loss Alternative to Ozempic?

Written by Jinfiniti Science on August 13, 2024. Posted in NAD, NAD+, Obesity and Weight Gain.

NAD+ overcomes insulin resistance without disastrous side effects.

Social media is burning up with images of celebrities who’ve dropped significant tonnage, but are mute about their methods.

This is an odd phenomenon, given the characteristic eagerness of this class to publicly pledge their allegiance to the newest fad, no matter how bizarre that craze might seem to the average person on the street. Yet, at each exhibition of luminary lipid loss, the same word is uttered in hushed whispers: Ozempic.

And we have to wonder, why the muted tones? If Ozempic is a miracle weight-loss drug, shouldn’t we be shouting about it from the rooftops? Turns out there are ample reasons to be wary, and even more reasons to choose a particular safe and effective alternative: the natural coenzyme NAD.

Step 1: Design a catchy ad campaign

Want to charge $1,200 a month for an injection whose benefits are decidedly short-term, and which puts patients at risk for numerous painful, debilitating side-effects, as well as a dispiriting rebound of the conditions they sought to alleviate in the first place? Then you must, must, must pick a catchy, long-forgotten pop song from the 1970s, whose original lyrics were all about the wondrous state of being in love.

Now you’ve got “Oh-oh-oh-Ozempic!” subliminally telling viewers of ubiquitous pharma commercials that “It’s magic.” Fossils of my era will remember the Scottish band Pilot cautioning listeners, “Never believe it’s not so!” But should we believe the advertising hype around Ozempic? Many sources, including those in the health and fitness sphere outside of Big Pharma, are telling us “No.”

What is Ozempic and why should I be skeptical?

According to the website Health.com¹, Ozempic a semaglutide, a “synthetic version of a human hormone called glucagon-like peptide one, or GLP-1.” Humans secrete GLP-1 when food reaches our gut.

It tells our brain that we’re full and tells our pancreas to get off the schneid and produce some insulin, the hormone that signals our cells to open wide and receive blood glucose.

When all works well, GLP-1 ensures that we don’t gorge ourselves and that the vacuoles of our cells widen, taking in glucose to convert to energy. This latter process also lowers our blood glucose levels, sparing us the consequences of diabetically high blood sugar.

People with type II diabetes either don’t produce enough insulin or suffer from extreme insulin resistance, so that while their insulin’s a knockin’, their vacuoles are sayin’ “Don’t come in.” (This is a problem with cell-signaling, one of the many cellular functions that depend heavily on the co-enzyme nicotinamide adenine dinucleotide, or NAD.)

Ozempic is designed to increase insulin production for type II diabetics who have had trouble getting their blood sugar under control with other methods. Ozempic is delivered via twice-monthly injections, at a cost of about $1,200 per month.

Health.com tells us, “After injection, semaglutide increases insulin production and lowers blood sugar. This causes the stomach to empty more slowly, reduces appetite, and makes people feel full.” So, it should come as no surprise that Ozempic has delivered another sought-after benefit: weight loss.

Is the bonus benefit just a dangerous illusion?

The Ozempic bonus has led overweight people, especially celebrities who can afford the high price tag, to request the drug for weight loss, a use for which the FDA has not approved it.

Yet, doctors seem willing to prescribe Ozempic for off-label use, a practice that is often controversial if not illegal. In fairness to these doctors, we should note that another semaglutide prescription, Wegovy, has FDA approval as a weight-loss drug. But should either of these synthetic hormone drugs be used for this purpose?

This lady in a lab coat says no. And we must listen because she is appropriately dressed. (Also note that she’s an MD, not an actress.)

Thank you, Dr. Annette Bosworth.

A litany of side-effects, some of which are deadly

If you’ve seen an O-O-O-Ozempic commercial, you’ve heard the recitation of side effects, which range from unpleasant to deadly. The mild variety includes:

Fatigue
Dizziness or vertigo
Discomfort and/or skin discoloration around the injection site
Increased heart rate
Changes in perception of taste
Digestive problems, such as belly pain, constipation, diarrhea, flatulence, burping, nausea, and vomiting

Ozempic patients have also started reporting hair loss².

The more serious side effects include:

Kidney problems, such as kidney failure
Low blood sugar
Pancreatitis
Gallbladder disease, such as cholecystitis or gallstones
Thyroid cancer
Allergic reactions

All of these are potentially fatal.

After reading these lists, the reasonable reader might wonder, “At what point do the risks outweigh the possible benefits?” For people who cannot control their diabetes, the disease is eventually fatal.

Other messy consequences include blindness and amputation of extremities. So, a roll of the dice with Ozempic might be in order.

Alternatives to a potentially deadly roll of the dice?

However, most people with type II diabetes can control their sugar through dietary and lifestyle modification. These changes are generally not easy, which is why many so people are open to taking a magic shot, courtesy of our consistently trustworthy friends at Big Pharma.

This mindset, which seems to be the basis for Ozempic’s marketing strategy, has really rankled celebrity trainer Jillian Michaels, who has voiced her concerns about Ozempic to Megyn Kelly (video below) and Bill Maher.

As Ms. Michaels explain, Ozempic treatment is necessarily short. And for many patients, the benefits sunset early, as their weight loss plateaus and the pounds rebound. Unfortunately, the side-effects seem to linger³ well beyond patients’ use of the drug.

Another reason for concern is the psychological effect Ozempic seems to have on type II diabetics, who should maintain a strict exercise regimen. According to a report from MSN, Ozempic seems to discourage overweight people from working out⁴.

Is NAD+ optimization a better way to manage insulin resistance?

Dr. Jin-Xiong She is a prominent microbiologist who has spent a significant portion of his career studying the relationship between cellular functions and age-related/metabolic diseases, including type II diabetes.

The precursor to type II diabetes is the condition we call insulin resistance, where the cells do not respond to the insulin’s signal.

This forces the pancreas to produce more insulin, eventually exhausting itself. When the body no longer produces its own insulin, a patient must take insulin orally or via injection. For people in a prediabetic state, insulin resistance causes stubborn weight gain, along with ancillary health problems.

Dr. She has studied the role of NAD in cellular functions, and in this short video, he explains four key benefits of NAD as they pertain to normal insulin sensitivity.

Unfortunately, people lose NAD due to age, stress, and lifestyle choices, such as a poor diet, smoking, alcohol consumption, and a sedentary lifestyle.

This can turn insulin sensitivity into insulin resistance. The good news is that replenishing lost NAD can return the system to healthy homeostasis. Replacing lost NAD is tricky, but Dr. She has developed a highly effective supplement he calls Vitality ↑® NAD+ Booster.

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NAD optimization: a safe, natural path to better health

One of the great benefits of Vitality ↑® NAD+ Booster is the increased energy one feels after just a few days of using the product. This can empower an overweight person with insulin resistance or type II diabetes to hit the gym and get the natural health benefits of exercise.

Many people have been able to reverse type II diabetes and return to good health through dietary and lifestyle modifications. Supplementing to achieve NAD optimization makes the process easier, so more patients should be able to improve their health for the long term.

Importantly, NAD is a natural compound, not a synthetic, so there’s no list of horrendous side effects. I’ve written in this column⁵ about the numerous health benefits I’ve experienced with Vitality ↑® NAD+ Booster. It’s precisely because of those health benefits that I asked Dr. She to make me an affiliate marketer for his company Jinfiniti Precision Medicine.

If you are struggling with insulin resistance or type II diabetes, I urge you to try this amazing product. Ask your doctor which is more likely to help you: the all-natural compound that’s an essential cofactor for virtually every cellular function, or the synthetic hormone with the catchy jingle, a monthly cost equal to your mortgage, and a list of side effects the length of the King James Bible.

O-O-O-I think I know what they’ll say.

Great news: Get started with NAD for only $28!

Vitality ↑® NAD+ Booster has never been more cost-effective than now, because Dr. She is offering an introductory, one-month supply for only $28 dollars with a monthly subscription. That’s a savings of 76 percent, and you can cancel the subscription any time, if you’re not thrilled with the results. Just follow this link: Start for $28!

Disclaimer: The column may contain affiliate links, which help support the website. When you clink on an affiliate link and make a purchase, the website receives a small commission at no additional charge to you. Thank you for your support.

Kevin Rush is an award-winning playwright and screenwriter. He’s the author of three novels, including The Lance and the Veil, an adventure in the time of Christ (which Kirkus Reviews calls “a big, bold Biblical saga to fire the Christian imagination”) and The Wedding Routine, (hailed by Online Book Club as a 4/4 Star romantic comedy delivering “nothing but comic gold”). Learn more at www.kevinrush.us.

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Author: Jinfiniti Science

NAD+ and Metabolic Function

NAD+ and Fat Tissues

The Science Behind NAD+ and Weight Loss

Clinical Research on NAD for Weight Loss

NAD+ Precursors and Their Weight Loss Effects

Does NAD IV Therapy Work for Weight Loss?

Potential Side Effects of NAD Supplementation

How to Increase NAD Levels for Weight Loss

Referenced Sources:

Understanding NAD+ and Why It Declines

Common Symptoms of NAD+ Deficiency

Fatigue and Low Energy

Cognitive Symptoms

Skin and Appearance Changes

Poor Sleep Quality

Mental Health and Mood Swings

Metabolic Health Issues

Severe NAD+ Deficiency Symptoms

Cardiovascular Impact of NAD+ Deficiency

NAD+ Deficiency in Specific Populations

How to Test if Your NAD Levels Are Low

How to Treat Low NAD Levels

Referenced Sources:

What is NAD?

Types of NAD Treatments

Oral NAD Supplements

NAD IV Therapy

Other NAD Therapies

Pros and Cons of NAD Supplements and IV Therapy

Effectiveness

Convenience

Cost

Safety and Side Effects

Choosing Between NAD Supplements or IV Therapy

Frequently Asked Questions

What are the benefits of NAD supplements?

Are NAD Supplements as Effective as IV?

Who should avoid or take NAD supplements?

Discover Your NAD+ Levels with Jinfiniti

Referenced Sources:

What is NAD IV Therapy?

Common Safety Concerns of NAD Therapy

Infection

Vein Irritation

Incorrect Dosage

Improper Administration

Quality and Sourcing of NAD Products

What are the Side Effects of NAD IV Therapy?

Common Short-Term Side Effects

Possible Long-Term Side Effects

The Safest Approach to NAD IV Therapy

Choose a Qualified Provider

Evaluate Your Health

Monitor Your NAD Levels Regularly

Oral NAD Supplements: A Safer Alternative to NAD IV Treatment

Final Thoughts: Is NAD IV Therapy Safe?

Referenced Sources

What is NAD IV Therapy?

How Much Does NAD IV Therapy Cost?

Add 20+ Healthy Years to Your Life

Additional Fees

Cost of Multiple NAD Therapy Sessions

Is NAD IV Therapy Covered by Insurance?

NAD IV Therapy vs Oral NAD Supplement Cost

Is the Cost of NAD IV Therapy Worth It?

Referenced Sources

I was surprised when my dear friend’s cognition declined dramatically overnight at age 94.

When my dear friend reached and passed his 90th birthday with a mind sharp as a tack I assumed he was all clear.

Marshall’s great mind and good memory were perfectly intact until one fateful day.

From one day to the next my friend had forgotten how to use both his cellphone and his computer.

A battery of cognitive tests with a gerontology professional confirmed that he was experiencing mild to moderate dementia.

What if Vitality NAD+ Booster, a NAD supplement formula and known neurotransmitter, could help?

At least 50-65% cognitively recovered.

He knows how to use his phone, he’s back at the computer, those bathroom issues are pretty much gone, and he’s using his walker and cane as well as he formerly had.

He is now back in charge of his meds and supplements because he began to remind me to give him doses as he remembered what to take and when.

Referenced Sources:

What is NAD IV Therapy?

Factors That Influence the Frequency of NAD IV Therapy

Individual Health Goals

When my dear friend reached and passed his 90^th birthday with a mind sharp as a tack I assumed he was all clear.