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Is Your Sex Life Over? Understanding Menopause, Libido, and NAD

Written by Jinfiniti Science on . Posted in , , , .

As women age, menopause can bring about significant changes, including shifts in sexual desire and satisfaction. 

For many, this transition can be challenging, affecting not only their own sense of self but also their relationships. It’s not uncommon to feel like your sex life is over, especially when faced with a loss of libido and arousal.

Take the experience of Jane (not her real name), a 60-year-old woman who has been struggling with a challenging menopause. 

Like many women in her situation, Jane’s sexual appetite has diminished, leaving her feeling like there’s nothing to miss. Despite having a loving and understanding husband, the lack of intimacy has started to take a toll on their relationship. 

While she tries to accommodate her husband’s needs, the situation has become increasingly difficult for both of them.

Jane’s story is not uncommon. Many men and women experience a decline in libido and arousal as they age, impacting their relationships and overall well-being. 

This decline can lead to feelings of inadequacy, low self-esteem, and even a sense of loss in the relationship.

Why does this happen? Why do you lose intimacy and sex drive as you age? Here are three science-backed reasons why.


In this article, we talk about…

  • The top three reasons for the loss of libido in women that you should be aware of.
  • The significant impact of low NAD levels on your sexual health, including reduced energy and hormonal imbalances.
  • How boosting NAD levels can reignite your passion and spice up your sex life, leading to a more fulfilling and intimate connection.

3 Reasons for the Loss of Libido in Women

libido and nad - jinfiniti precision medicine

Hormonal Changes

Hormonal changes, especially during menopause, can have a profound impact on female libido. 

The decrease in estrogen levels that accompanies menopause can lead to physical changes such as vaginal dryness, thinning of the vaginal walls, and decreased blood flow to the pelvic region.1 

These changes can result in discomfort during sex, making it less enjoyable and leading to a decrease in sexual desire.

Furthermore, testosterone, although often thought of as a male hormone, also plays a crucial role in female sexual function.2 

Women produce testosterone in their ovaries and adrenal glands, and a decline in testosterone levels can lead to a decrease in sexual desire and arousal.

A study published in the Journal of Clinical Endocrinology & Metabolism investigated the effects of testosterone therapy on postmenopausal women with low libido. 

The study found that testosterone treatment significantly improved sexual function, including desire and arousal3, in these women, highlighting the importance of hormone balance in maintaining a healthy libido.

Overall, the hormonal changes that occur during menopause can have a profound impact on female sexual function, underscoring the importance of addressing these hormonal imbalances in managing low libido.

Stress and Fatigue

High levels of stress and fatigue can significantly affect a woman’s libido. 

The demands of daily life, including work, family responsibilities, and other stressors, can lead to increased levels of cortisol, the primary stress hormone. 

Elevated cortisol levels can disrupt the balance of other hormones, such as estrogen and testosterone,4 which are crucial for sexual desire and arousal. Additionally, chronic stress can lead to feelings of fatigue and exhaustion, leaving little energy or motivation for sexual intimacy.

A study published in the Journal of Sexual Medicine discovered that high levels of stress were associated with an increased risk of sexual dysfunction in women, including difficulties with arousal, desire, and orgasm.5 

These findings suggest that managing stress and reducing fatigue are important factors in maintaining a healthy libido and sexual function in women.

Low NAD Levels: Nicotinamide 

As individuals age, NAD levels tend to decrease, potentially affecting energy levels and mood, both of which are crucial for a healthy sex drive.

A study published in the journal Cell Metabolism found that declining NAD+ levels disrupt cellular communication, leading to a “pseudo-hypoxic” state that resembles low oxygen conditions6

This state can negatively affect cellular function and contribute to age-related health issues, including reduced energy levels and potentially, decreased libido.

Another study published in Nature Communications demonstrated that increasing NAD+ levels improved mitochondrial function, stem cell function, and overall lifespan in mice7, highlighting the importance of NAD+ in maintaining cellular health and function.

These studies suggest that maintaining optimal NAD+ levels may play a role in supporting overall health, including sexual health and libido, especially as individuals age and NAD+ levels naturally decline.

Here at Jinfiniti, we have found that customers who consistently use Vitality ↑® NAD+ Booster experience significant improvements in their sex drive and function. 

In fact, many have been able to rekindle the intimacy they once lost with their partners by adding Vitality ↑® NAD+ Booster to their daily routine.

How NAD Can Boost Your Libido

libido and nad - jinfiniti precision medicine

Increased Energy Levels

NAD+ is a crucial coenzyme involved in cellular energy production and plays a key role in regulating various cellular processes, including metabolism and DNA repair. 

As we age, NAD+ levels naturally decline, which can lead to a decline in cellular function and contribute to age-related health issues, including decreased libido and sexual function.

Supplementation with NAD+ precursors, has been shown to increase NAD+ levels in cells. 

This increase in NAD+ levels can improve mitochondrial function, enhance cellular energy production, and promote overall cellular health.8

By improving cellular energy production and overall cellular function, NAD+ supplementation may help improve energy levels, mood, and vitality, all of which are important factors in sexual desire and activity. 

Improved Mood

NAD is involved in various metabolic processes, including those related to neurotransmitter function9

Neurotransmitters are chemical messengers in the brain that play a crucial role in regulating various bodily functions, including mood, stress response, and sexual function. 

Dopamine, serotonin, and norepinephrine are neurotransmitters that are particularly important for sexual desire and arousal.

Dopamine is often referred to as the “pleasure neurotransmitter”10 and plays a key role in the brain’s reward system. It is involved in feelings of pleasure and reward, including those associated with sexual activity. 

It is also involved in the regulation of sexual desire, and imbalances in dopamine levels may contribute to changes in libido.

Serotonin is another neurotransmitter that plays a role in regulating mood and sexual function11

Low levels of serotonin have been associated with an increase in impulsive behaviors, including those related to sexual activity. 

On the other hand, high levels of serotonin can lead to a decrease in sexual desire and arousal. Maintaining optimal serotonin levels is important for a healthy sex drive.

Norepinephrine is a neurotransmitter that is involved in the body’s stress response12. It plays a role in increasing arousal and alertness, which can be beneficial for sexual activity. 

However, chronic stress can lead to an overproduction of norepinephrine13, which can negatively impact sexual function and libido.

By supporting NAD+ levels, supplementation may help maintain optimal neurotransmitter function, which can have a positive impact on sexual desire and arousal, as mood plays a significant role in sexual health and satisfaction.

Enhanced Cellular Function

NAD is essential for maintaining healthy cellular function. 

By supporting cellular health, NAD supplementation may help improve overall bodily functions, including those related to sexual health. This can result in enhanced libido and sexual function.

Mitochondria, often referred to as the “powerhouses” of the cell, are responsible for producing the energy (ATP) needed for cellular function. 

By improving mitochondrial function, NAD+ supplementation may help enhance overall cellular function, including those related to sexual health. 

This can result in improved libido and sexual function, highlighting the potential benefits of NAD+ supplementation for sexual health and vitality.

Mitochondria are not only crucial for energy production but also play a role in estrogen synthesis,14 which is important for maintaining vaginal health and lubrication, both of which are essential for a healthy sex life.

A study published in the journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) found that mitochondria play a crucial role in regulating estrogen receptor signaling15, which is important for various physiological processes, including those related to sexual health.

As women age, NAD levels tend to decline, leading to mitochondrial dysfunction and reduced energy production. 

This decline in mitochondrial function can affect various bodily functions, including those related to sexual health. 

By improving mitochondrial function through NAD supplementation, women may experience increased energy levels, which can positively impact libido and sexual desire.

In conclusion, menopause and aging can bring about changes in your sex life, but it doesn’t have to mean the end of intimacy. 

By communicating openly with your partner, prioritizing self-care, and considering supplements like NAD from Jinfiniti, you can take proactive steps to boost your libido and reignite the spark in your relationship.

Two Steps to Boost Your Libido

libido and nad - jinfiniti precision medicine

Step 1: Test Your NAD levels

Is your NAD levels low, borderline, or high?  

The Intracellular NAD® Test is the first and only NAD test that can help you determine if you are deficient in NAD, if your NAD supplement is working, or if you are taking the optimal dosage for your supplement. 

This test provides you with the information you need to optimize your NAD levels without the guessing game.

Moreover, it gives you actionable data to help you find an effective and affordable product and the correct dosage to optimize your NAD level.

Step 2: Take Vitality ↑® NAD+ Booster

If there’s one supplement we trust to support healthy levels of NAD in your body, it’s none other than Vitality ↑® NAD+ Booster by Jinfiniti

Vitality ↑® NAD+ Booster is a clinically validated formulation consisting of NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide that work synergistically to help:

  • Boost energy and improve performance
  • Improve sleep quality
  • Support inflammation, muscle, and joint pains
  • Support healthy allergic and asthmatic symptoms
  • Improve mental clarity and dementia symptoms
  • Support functions of many organs (liver, kidney, heart, thyroid, fertility)…

This supplement supports healthy NAD levels to revitalize your cells, optimize your mitochondria, and boost your libido so you can perform in bed with your partner. 

Remember: reaching menopause isn’t the end of your sex life. 

You can always boost your libido and sex drive with the help of NAD supplementation, along with a healthy diet and exercise.

You can also take advantage of the NAD Optimization® Bundles, where you can get 2 Intracellular NAD® tests and 1 Vitality ↑® NAD+ Booster supplement — and get one free supplement and free consultation.

This package allows you to reveal your current NAD level, the optimal dosage for NAD+ precursor supplements, and health benefits from optimized NAD levels.

If you want to improve your sex drive and libido even as you age…

Grab the NAD Optimization® Bundles here.

Referenced Sources:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800285/ ↩︎
  2. https://www.medicalnewstoday.com/articles/324887 ↩︎
  3. https://www.researchgate.net/publication/23454588 ↩︎
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703719/ ↩︎
  5. https://pubmed.ncbi.nlm.nih.gov/33303390/ ↩︎
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076149/ ↩︎
  7. https://www.science.org/doi/10.1126/science.aaf2693 ↩︎
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973386/ ↩︎
  9. https://www.pnas.org/doi/10.1073/pnas.0705510104 ↩︎
  10. https://www.sciencedaily.com/releases/2023/12/231201173208.htm ↩︎
  11. https://www.ncbi.nlm.nih.gov/books/NBK560856/ ↩︎
  12. https://www.sciencedirect.com/topics/psychology/norepinephrine ↩︎
  13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199300/ ↩︎
  14. https://www.intechopen.com/chapters/58585 ↩︎
  15. https://www.pnas.org/doi/full/10.1073/pnas.0306948101 ↩︎
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