Why NAD Levels Matter for Fat Burning and Weight Loss

Imagine a life where simple tasks like tying your shoes or taking a leisurely walk become daunting challenges. This is the reality for millions worldwide struggling with obesity, a condition that not only affects physical health but also imposes significant limitations on everyday life.

According to the World Health Organization (WHO), obesity has nearly tripled since 1975, with over 650 million adults classified as obese in 2016.¹ This staggering increase is not just a statistic but a reflection of lives constrained by excess weight.

Obesity isn’t just about appearance; it’s about a loss of freedom. It’s about the inability to fully engage in activities that bring joy and fulfillment. It’s about the things you can’t do—like comfortably fitting into a movie theater seat, enjoying a hike with friends, or playing with your children without feeling out of breath.

But it’s not just the physical limitations; obesity can also impact mental health, leading to feelings of isolation, low self-esteem, and depression.

In this article, we’ll uncover how NAD can support your weight loss journey and optimize your health.

3 Reasons for Weight Gain as You Age

Metabolic Changes

Metabolism refers to the complex set of chemical reactions² that occur in the body to maintain life. 

One aspect of metabolism that significantly impacts weight management is the basal metabolic rate (BMR)³, which is the amount of energy expended by the body at rest to maintain basic physiological functions. 

One of the primary reasons for the decrease in metabolism with age is the loss of muscle mass, known as sarcopenia.⁴ 

Muscle tissue is metabolically active and requires more energy to maintain than fat tissue. 

As muscle mass decreases, the body’s overall energy expenditure decreases, leading to a lower BMR.

Low Estrogen and Testosterone Levels

Hormones play a crucial role in regulating metabolism, appetite, and fat storage in the body. As people age, changes in hormone levels can occur, contributing to weight gain.

This has been shown in a study published in the journal Endocrine Reviews, where changes in estrogen and testosterone levels can contribute to weight gain in men and women as they age⁵.

Estrogen in Women

During menopause, women experience a significant decrease in estrogen levels. 

Estrogen helps regulate metabolism and body weight⁶, and its decline can lead to an increase in abdominal fat. 

Abdominal fat, also known as visceral fat, is particularly harmful as it is associated with an increased risk of heart disease, diabetes,⁷ and other health problems.

Testosterone in Men

In men, testosterone levels naturally decline with age, leading to a decrease in muscle mass and an increase in body fat, especially around the abdomen. 

Muscle mass is important for maintaining a higher metabolism⁸, so a decrease in muscle mass can contribute to a slower metabolism and weight gain.

Low NAD Levels

Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme that plays a critical role in various cellular processes, including energy metabolism and DNA repair. 

As people age, NAD levels tend to decline, which can have several implications for overall health, including weight gain.

One key role of NAD in metabolism is its involvement in the regulation of mitochondrial function.⁹ 

Mitochondria are the powerhouse of the cell, responsible for generating energy in the form of adenosine triphosphate (ATP). NAD is a key player in the electron transport chain, a series of reactions that occur in the mitochondria to produce ATP.

As NAD levels decline with age, mitochondrial function can be impaired, leading to decreased energy production. 

This can contribute to a decrease in overall energy expenditure, making it easier to gain weight.

A study published in the journal Cell Metabolism investigated the effects of increasing NAD levels in mice¹⁰. 

The study found that boosting NAD levels in older mice improved mitochondrial function, increased energy expenditure, and led to a decrease in weight gain compared to control mice.

The mechanism behind these effects involves the role of NAD in regulating sirtuins¹¹, a class of proteins that play a role in regulating cellular processes related to aging and metabolism. 

NAD is a coenzyme for sirtuins, and higher NAD levels can enhance the activity of sirtuins,¹² leading to improved mitochondrial function and increased energy expenditure.

5 Benefits of NAD on Fat and Weight Loss

Increasing NAD levels in the body has been shown to have several benefits related to fat burning and weight loss. 

Improved Metabolic Function

NAD is involved in several metabolic pathways, including the breakdown of fats (lipolysis) for energy¹³. By increasing NAD levels, the body may be able to more efficiently convert stored fat into energy, potentially leading to weight loss.

Increased Energy Expenditure

NAD is essential for the function of mitochondria, the powerhouse of the cell where energy production occurs. By enhancing mitochondrial function, NAD may help increase energy expenditure¹⁴, which can contribute to weight loss.

Regulation of Circadian Rhythms

NAD plays a role in regulating circadian rhythms¹⁵, which can impact metabolism and energy balance. By maintaining healthy circadian rhythms, NAD may help support weight loss efforts.

Enhanced Cellular Repair and Function

NAD is involved in DNA repair and cellular maintenance processes. By supporting these functions, NAD may help optimize cellular health¹⁶, which is important for overall metabolic function and weight management.

Potential Appetite Regulation

Some studies suggest that NAD may play a role in appetite regulation¹⁷. By influencing signaling pathways involved in hunger and satiety, NAD may help reduce calorie intake, supporting weight loss.

A study published in the journal Cell Metabolism found that increasing NAD levels in human cells led to increased mitochondrial function and energy expenditure, which are important factors in fat-burning and weight loss.¹⁸

This only shows that NAD shows promise as a potential aid in fat burning and weight loss by improving metabolic function, increasing energy expenditure, and supporting overall cellular health. 

For supporting healthy NAD levels and achieving your weight loss goals, Vitality ↑® NAD+ Booster stands as our trusted choice in NAD supplementation.

For better results, it’s best to check your NAD levels with our Intracellular NAD test to determine if they are within the normal range, low, or high. This information can help you adjust the amount of Vitality ↑® NAD+ Booster to take for optimal results.

Ready to lose weight and trim off stubborn fats?

Your Next Steps…

Step 1: Order the Intracellular NAD test today.

Order the Intracellular NAD test today and use it as soon as it arrives. This test can help you determine if you are deficient in NAD, assess the effectiveness of your NAD supplement, and find the optimal dosage for your needs.

Additionally, the test provides actionable data to help you adjust the dosage of Vitality ↑® NAD+ Booster, optimizing your NAD levels and help you lose weight. 

⇒ You can get the Intracellular NAD® Test here!

Step 2: Take Vitality ↑® NAD+ Booster. 

This clinically validated formulation includes NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide, which synergistically work to:

• Revitalize your cells
• Optimize your mitochondria
• Manage your appetite
• Help you burn fat fast, , just like Anna…

A Doctor friend in South America asked me order and take this to him. After reading about it and him speaking of his results I have ordered for my Family too. We are all using it and seeing results. 

It is helping me with fatigue, weight loss and over eating. I am finally able to try and diet. 

Great product and easy to take. I am also having my daughter with Asthma and fibro take it and she is feeling better.

⇒ You can get Vitality ↑® NAD+ Booster here.

To save even more, you can take advantage of the NAD Optimization® Bundles, where you can get…

• 2 Intracellular NAD® tests
• 1 Vitality ↑® NAD+ Booster supplement
• one free supplement and…
• a free consultation.

Start by using the first Intracellular NAD® test to reveal your current NAD levels. Then, take Vitality ↑® NAD+ Booster for a month.

Afterwards, use the second Intracellular NAD® test to identify your new, optimized levels after taking our NAD supplements. You’ll be pleasantly surprised by how much your levels have improved.

If you’re unsure about what to do or have questions about how to start or interpret your results, you can book your free consultation.

Grab the NAD Optimization® Bundles here — SAVE $178 today.

If you want to lose weight, achieve the body of your dreams, and be healthy…

Order Vitality ↑® NAD+ Booster and Intracellular NAD® Test, or Grab the NAD Optimization® Bundles here to save even more.

Our Guarantee

If our Vitality ↑® NAD+ Booster fails to increase your NAD levels within 60 days, we will gladly refund your supplement purchase. Please note that tests are non-refundable.

Referenced Sources:

1. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight ↩︎
2. https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/metabolism#: ↩︎
3. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/basal-metabolic-rate# ↩︎
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804956/ ↩︎
5. https://www.ncbi.nlm.nih.gov/books/NBK279053/ ↩︎
6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964739/ ↩︎
7. https://www.healthdirect.gov.au/how-to-reduce-visceral-body-fat-hidden-fat# ↩︎
8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661116/ ↩︎
9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963035/ ↩︎
10. https://www.researchgate.net/publication/301692871 ↩︎
11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973386/#: ↩︎
12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880/ ↩︎
13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7963035/ ↩︎
14. https://pubmed.ncbi.nlm.nih.gov/30230244/ ↩︎
15. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665902/ ↩︎
16. https://puredropiv.com/nad-iv-therapy/weight-loss-and-metabolic-function/ ↩︎
17. https://www.mdpi.com/2227-9059/11/9/2560 ↩︎
18. https://pubmed.ncbi.nlm.nih.gov/32369735/ ↩︎