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NAD: A New Cure for Seasonal Allergies

Written by Jinfiniti Science on . Posted in , .

As the spring season unfurls its vibrant colors and the air fills with the gentle buzz of life, many individuals brace themselves for the less welcome arrival of pollen season. 

For those with allergies, this time of year can be particularly challenging, with symptoms ranging from mild discomfort to severe reactions that significantly impact daily life. 

However, emerging research into the molecular and cellular mechanisms of nicotinamide adenine dinucleotide (NAD) offers a glimmer of hope for managing these seasonal woes more effectively.

Understanding NAD and Its Role in the Immune System

 - jinfiniti precision medicine

Allergies occur when your immune system overreacts to substances that are normally harmless1, such as pollen, dust mites, or certain foods. 

When you encounter these substances, known as allergens, your immune system produces antibodies that signal your body to release chemicals like histamine, leading to symptoms such as sneezing, itching, or swelling.

NAD (Nicotinamide Adenine Dinucleotide) plays a crucial role in the immune system by supporting cellular processes that regulate inflammation and immune responses. 

Recent studies have begun to shed light on how NAD influences immune responses, particularly in the context of allergies. Here are four ways.

1. Regulation of Immune Cells

The immune system is a complex network of cells and proteins that defends the body against infection. However, in people with allergies, this system misidentifies harmless substances like pollen as dangerous invaders, triggering an allergic reaction.

NAD influences the function and regulation of various immune cells, including T cells, B cells, and macrophages. These cells are pivotal in orchestrating the body’s response to allergens.

By modulating the activity and differentiation of these cells, NAD can potentially alter the immune system’s reactivity to allergens, offering a new avenue for allergy management.

2. Reduction of Inflammatory Response

Inflammation is a hallmark of allergic reactions, manifesting as redness, swelling, and discomfort. NAD plays a role in the signaling pathways that regulate inflammation.

By influencing these pathways, NAD can potentially modulate the body’s inflammatory response to allergens. This modulation could lead to a reduction in the severity of allergic symptoms, making pollen season more bearable for those affected.

3. Regulation of Sirtuin Activity

Sirtuins are a family of enzymes dependent on NAD, known for their role in promoting cellular health, longevity, and stress resistance. They also play a crucial part in regulating inflammation and immune responses.

Activation of sirtuins could help mitigate the inflammatory processes associated with allergic reactions. Since sirtuins require NAD to function, maintaining optimal NAD levels is crucial for their activity. This connection highlights another pathway through which NAD can influence allergic responses.

4. NAD Precursors Suppress Hyper Allergic Reactions

In 2022, researchers in Korea identified a lot of hope in hyper allergic responses in mice using NAD precursors.

“Animal research has shown that the NAD+ precursors inhibit the release of pro-inflammatory proteins called histamines from white blood cells called mast cells. Since mast cell histamine release is a hallmark of the anaphylactic response, this finding provides a glimmer of hope for boosting NAD+ to ward off these allergic reactions. 

The researchers summarize their findings: “The findings showing that NAD+ precursor treatment reduces the mast cell release of the proinflammatory proteins, histamine and IL-6 begs the question of whether NAD+ precursors could help with common allergies. Anaphylaxis is on the severe end of the allergic response spectrum, and many of the same cellular processes occurring in anaphylaxis happen in common allergies.

Namely, histamine and IL-6 release occur frequently and to varying degrees with common allergies. Future human trials could look at the effects of NAD+ precursor supplementation on blood inflammatory factor levels or examine the severity of symptoms in people with common allergies to, for example, tree pollen.”

Jinfiniti’s Vitality ↑® NAD+ Booster: Proven Relief for Allergy Sufferers

For those seeking relief from allergies, Vitality ↑® NAD Boost offers a promising solution.

Vitality ↑® NAD+ Booster has established itself as the most powerful NAD-optimizing substance on the market, but many people are experiencing a significant reduction in those nagging springtime allergies. 

As allergies are subsiding, you can enjoy the beauty of nature and potentially the pets you adore without the headaches of sneezing and sniffling.

“I originally bought this supplement for its longevity support, but to my surprise, it helped with my allergies! We have a dog who sadly gives me lots of sneezing fits, stuffy noses, and occasional asthmatic reactions.


I have taken everything under the sun that the doctor has prescribed. Some of those things have helped mildly, others not so much, but I know every pharmaceutical comes with a cost.  I am happy to say I am now able to nix the daily Zyrtec that was previously needed to cope after a month of using Vitality and am using only Singulair and my emergency inhaler. 


Next up, I will try to ease out of a Singulair. Wish me luck! And thanks for the great product!”

-Emily P wrote on our website on 1/28/24.

Conclusion

As we navigate the beauty and challenges of spring, understanding the intricate relationship between NAD and allergies offers a new perspective on managing seasonal allergies.

The regulation of immune cells, reduction of inflammatory responses, and regulation of sirtuin activity are just the beginning of unraveling NAD’s full potential in allergy management.

With Vitality ↑® NAD Boost demonstrating tangible benefits for individuals, including those at the helm of its creation and promotion, NAD boosting emerges as a proven and effective strategy for enhancing quality of life during allergy season.

As research continues to evolve, the promise of NAD in allergy management shines brighter, offering hope and relief to those seeking to enjoy the spring season to its fullest.

Referenced Sources:

  1. https://www.ncbi.nlm.nih.gov/books/NBK447112/ ↩︎
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