Does NAD+ Help With Menopause Symptoms?

Written by Jinfiniti Science on December 6, 2024. Posted in NAD+, Menopause, NAD, NAD+ Precursors. No Comments on Does NAD+ Help With Menopause Symptoms?

Hot flashes, night sweats, mood swings, sleep disturbances, and memory loss—these are just a few of the challenging symptoms women experience during menopause.

While they are often considered a natural part of the transition, these symptoms can severely impact your daily life, leaving you feeling drained, frustrated, and disconnected from your usual self.

The good news is that you don’t have to just accept them. There are effective ways to manage—and even alleviate—these discomforts.

One promising approach involves a critical coenzyme called NAD+ (nicotinamide adenine dinucleotide). Replenishing your body’s NAD+ and supporting cellular health may ease and even alleviate menopause symptoms, helping you feel more like yourself during this transition.

In this article, we discuss…

How menopause symptoms impact daily life and why they shouldn’t be accepted as inevitable
The connection between NAD+ depletion and ovarian aging through CD38 enzyme activity
How NAD+ supports key biological processes during menopause
Strategies for restoring NAD+ levels to manage menopause symptoms effectively

Common Symptoms of Menopause

AN image of a woman suffering from menopause

Menopause is a natural phase in a woman’s life that marks the end of her reproductive years,¹ typically occurring in her late 40s to early 50s. During this time, estrogen levels fluctuate and eventually decline, leading to a range of physical and emotional changes, including:

Hot flashes and night sweats
Mood changes and irritability
Fatigue and low energy
Sleep disturbances
Cognitive issues (brain fog)
Vaginal dryness
Weight gain
Bone density loss
Lower libido
Loss of skin elasticity
Health problems due to hormonal changes

While these symptoms are often considered a normal part of aging, they can be overwhelming and disrupt your daily life. But you don’t have to simply endure them. By understanding what’s happening, you can take control and take proactive steps to help you live a healthy, balanced life—even during menopause.

NAD+ and Ovarian Aging

Ovarian aging is the gradual decline in ovarian function² that comes with age. As you enter your late 30s and 40s, changes in your hormones, such as reduced estrogen, can cause irregular periods and fewer high-quality eggs.

One of the reasons for this? A decrease in NAD+ levels as you age.

While NAD+ decreases across the body, the ovaries experience a more rapid decline³, affecting their function. This accelerated depletion of NAD+ is largely driven by an enzyme called CD38.

Research shows that CD38 activity increases in aging ovaries⁴, making them more vulnerable to a faster depletion of NAD+ compared to other tissues. This loss plays a major role in ovarian aging, leading to a decrease in ovarian follicles and a drop in estrogen production, which, in turn, causes common menopausal symptoms like hot flashes and mood swings.

But that’s not all. Low NAD+ levels in the ovaries are linked to a range of issues that affect reproductive health, including:

Reduced egg (oocyte) quality
Follicle depletion
Changes in gene expression related to aging, DNA repair, and inflammation

In fact, a recent study published in Ovarian Research found that low NAD+ levels can impair the energy metabolism of oocytes⁵, reducing their metabolic activity and impacting egg quality. This decline can have a major effect on fertility and reproductive health.

In addition to these metabolic changes, reduced NAD+ also alters gene expression in the ovaries, particularly genes involved in cellular aging and inflammation⁶. This creates a cycle that accelerates the aging process, leading to further declines in reproductive health.

Here’s the good news: you can turn things around.

By targeting CD38, you can potentially reverse some of the damage caused by NAD+ depletion in the ovaries. This has been shown in a study published in Nature, where researchers found that inhibiting or deleting CD38 significantly boosts NAD+ levels in the ovaries⁷, helping improve egg quality and even preserving fertility in aging mice.

This research suggests that by raising NAD+ levels and regulating CD38, you can significantly support ovarian health and even preserve fertility as you age. CD38 can be inhibited by flavonoids like apigenin and quercetin⁸, which is a main ingredient in our SenoAid senolytic supplement.

Key Takeaway: Research suggests that declining NAD+ levels in aging ovaries, driven by increased CD38 enzyme activity, significantly impact reproductive health and fertility, but targeting CD38 with specific compounds may help preserve ovarian function.

How NAD+ Can Relieve Menopause Symptoms

An image of an aging woman suffering from menopause

Maintaining optimal NAD+ levels during menopause is associated with several biological processes that influence common symptoms:

Cellular energy production: NAD+ serves as a critical coenzyme in mitochondrial function, directly impacting energy levels and fatigue resistance
Brain cell efficiency: Adequate NAD+ helps support neuronal health and cognitive function through enhanced mitochondrial activity and SIRT1 activation
Circadian rhythm regulation: NAD+ is essential for proper circadian rhythm function through the NAMPT-mediated salvage pathway, influencing sleep patterns
Cellular repair mechanisms: NAD+ enables DNA repair processes through PARP activation, supporting overall cellular health
Metabolic function: As a key metabolic regulator, NAD+ helps maintain efficient energy utilization and metabolic flexibility

While NAD+ levels naturally decrease during menopause, maintaining optimal cellular concentrations can support the body’s ability to manage this transition effectively.

NAD+ and Libido During Menopause

When you reach menopause, it’s not just the hot flashes and sleepless nights that can throw you off—it’s your libido, too. If you’ve been feeling a little less interested, you’re not alone.

But why does this happen?

The answer lies in NAD+. As we went over earlier, our NAD+ levels naturally decline with age, and this affects many processes in our bodies, from energy production to hormone regulation.

As menopause sets in, declining levels of estrogen and testosterone can naturally lower your sex drive even more. On top of that, reduced NAD+ levels can leave you feeling drained, irritable, and stressed⁹—none of which help your desire.

Fortunately, increasing NAD+ might be just what you need to reignite that spark. Here’s why:

Hormonal Balance: NAD+ supports the hormones that drive your libido¹⁰, including estrogen and testosterone. By boosting NAD+ levels, you help keep those hormones in check.
Neuroprotection: NAD+ protects your brain and reduces oxidative stress¹¹, which can improve mood, lower stress, and promote arousal.
More Energy: NAD+ fuels your cells, boosting your overall energy¹² and giving you more vitality for intimacy.
Better Mood: By fighting fatigue and mood swings¹³, NAD+ helps you feel emotionally balanced and ready to enjoy a deeper connection.

With optimal support for your NAD+ levels, you can reclaim not just your energy and vitality but your libido as well, bringing back the passion you thought menopause had taken away.

Restoring NAD+ Levels Before and After Menopause

NAD+ precursors are compounds that our cells can use to generate new NAD+ molecules. The most well-studied and effective precursors include:

Nicotinamide Mononucleotide (NMN)
Nicotinamide Riboside (NR)
Nicotinamide (a form of vitamin B3)

Supplementing with these precursors has been shown in studies to raise NAD+ levels in tissues throughout the body. As we have already seen, restoration of NAD+ can help reignite the cellular engines that power our metabolism, repair damaged DNA, activate longevity genes, and enable our cells to function at more youthful levels.

For women seeking a comprehensive NAD+ restoration strategy, products that combine multiple precursors may offer additional benefits. Scientifically formulated supplements, like our Vitality ↑® NAD+ Booster, provide a synergistic blend of NMN, Nicotinamide, and other bioactive ingredients to optimize NAD+ production and support healthy aging processes through menopause and beyond.

Whether you are proactively planning for menopause or already navigating this transition, incorporating NAD+ precursors into your wellness routine can provide a foundational strategy for nourishing cellular vitality. By restoring and maintaining healthy NAD+ levels, you can equip your cells with the resources they need to thrive, empowering you to age with resilience and grace.

Test Your NAD Levels Today

An image of a glowing matured woman taking supplement

While research clearly shows the connection between NAD+ and menopausal health, every woman’s journey is unique. The key to creating a personalized approach lies in knowing your precise cellular NAD+ levels.

Our Intracellular NAD® test provides precise measurements of your cellular NAD+ levels, complete with a detailed personal report and expert recommendations. You’ll understand exactly where your levels stand compared to optimal ranges, enabling you to make targeted decisions about your health. Plus, you’ll gain access to an exclusive webinar with our chief scientist, Dr. Jin-Xiong She, to deepen your understanding of NAD+ and its role in aging.

Don’t let declining NAD+ levels control your menopause experience. Get tested today and take the first step toward a more balanced, energetic you.

ORDER YOUR NAD+ TEST

Referenced Sources:

Can NAD+ Help Treat Alzheimer’s Disease and Dementia?

Written by Jinfiniti Science on December 2, 2024. Posted in NAD+, Memory Loss and Brain Fog, NAD, NAD+ Precursors, Neurological Diseases. No Comments on Can NAD+ Help Treat Alzheimer’s Disease and Dementia?

Alzheimer’s disease is affecting more people than ever, with 6.7 million Americans aged 65 and older living with it today. By 2050, that number is expected to more than double. Globally, over 55 million people are dealing with Alzheimer’s or other forms of dementia, creating challenges not just for them, but for their families too.

Right now, most treatments focus on managing symptoms, not fixing the root of the problem. That’s why there’s a growing push for new, more effective solutions—and nicotinamide adenine dinucleotide (NAD+) might be one of them.

NAD+ is the coenzyme behind every cell’s ability to thrive – it drives energy production, repairs DNA, and governs how your genes are expressed. As we age, NAD+ levels naturally decline, and this decrease is associated with neurodegeneration and cognitive impairment—hallmarks of conditions like Alzheimer’s disease.

A growing body of research is examining the relationship between NAD+ and neurodegenerative conditions, with studies suggesting that maintaining healthy NAD+ levels could help shield against the devastating effects of Alzheimer’s and dementia.

So, what makes this coenzyme so compelling for keeping our minds sharp as we age?

In this article, you will discover:

The critical relationship between NAD+ and neurodegeneration, exploring how this essential coenzyme impacts brain health at the cellular level
Clinical evidence supporting NAD+ supplementation in Alzheimer’s disease, including detailed research on nicotinamide, NMN, and nicotinamide riboside
Practical NAD+ treatment approaches, from IV therapy to scientifically-validated precursor compounds like Vitality ↑® NAD+ Booster
The importance of testing and monitoring NAD+ levels to proactively support cognitive health and prevent decline

The Link Between NAD+ and Neurodegeneration

Your cells rely on NAD+ like a conductor relies on their baton – the coenzyme coordinates numerous biological processes with precision that determines how well your body functions at its most fundamental level.

As we age, NAD+ levels in various tissues, including the brain, significantly decrease¹. This decline has been linked to the development of various age-related conditions, including neurodegenerative diseases like Alzheimer’s and Parkinson’s.²

NAD+ is essential for mitochondrial function and energy production. In neurodegenerative diseases, decreased NAD+ levels leads to multiple factors that contribute to neuronal death and axonal degeneration, hallmarks of these diseases:

Impaired mitochondrial function³
Increased reactive oxygen species (ROS) production⁴
Compromised cellular energy metabolism⁵
Impaired DNA repair mechanisms and reduced sirtuin activity⁶

The decline in NAD+ levels during aging and neurodegeneration is primarily due to:

Increased NAD+ consumption by enzymes such as CD38 and PARPs
Reduced expression of NAMPT, a key enzyme in the NAD+ salvage pathway
Activation of SARM1, a recently discovered NAD+ hydrolase that can rapidly deplete neuronal NAD+ levels⁷

Perhaps most intriguingly, reduction in NAD+ levels occurs before the onset of neurodegenerative symptoms, suggesting it may contribute to disease progression rather than being merely a consequence⁸.

Clinical Evidence for NAD+ in Alzheimer’s Disease

As Alzheimer’s disease (AD) becomes increasingly prevalent, researchers are exploring innovative therapies like NAD+ precursors to combat this devastating condition. But is NAD+ a potential treament for Alzheimer’s or just another overhyped trend? Let’s look at the evidence.

Nicotinamide (NAM) vs Placebo

A 2021 review published in Frontiers in Cell and Developmental Biology⁹ provides a comprehensive overview of the systematic therapeutic evidence for NAD+ and its precursors in Alzheimer’s disease models.

NAM, the amide form of vitamin B3, showed significant potential in seven preclinical trials for Alzheimer’s disease treatment:

NAM treatment improved spine density in neurons from AD mice, suggesting a neuroprotective role.¹⁰
A controlled delivery system of NAM reduced cognitive impairment and decreased phosphorylated tau in early-stage AD rats.¹¹
NAM pretreatment reduced expression of genes associated with AD and increased SIRT1 in brain tissues.¹²
NAM supplementation protected against Aβ-induced oxidative stress and reduced markers of cell death in rat AD models.¹³
Long-term NAM treatment improved cognitive performance, preserved mitochondrial integrity, and reduced AD pathology in mice.¹⁴
NAM reduced phosphorylated tau and prevented cognitive deficits in a mouse model of AD.¹⁵

More recently, a phase 2a proof-of-concept trial¹⁶ investigated the use of nicotinamide (a form of vitamin B3 and NAD+ precursor) in early Alzheimer’s disease:

47 participants received either 1500 mg of nicotinamide twice daily or placebo for 12 months.
Treatment resulted in significantly less change on the Clinical Dementia Rating-Sum of Boxes (CDR-SB) compared to placebo.
While not statistically significant, changes in cerebrospinal fluid (CSF) biomarkers favored nicotinamide.
The therapy showed a safe profile with balanced adverse events.

Nicotinamide Mononucleotide (NMN) vs Placebo

Outlined in the same 2021 review as above, NMN, a direct precursor to NAD+, has demonstrated efficacy in four AD models:

NMN improved memory in transgenic nematode AD models through a mechanism dependent on mitophagy.¹⁷
NMN treatment decreased Aβ production, synaptic loss, and inflammation in transgenic AD mice by inhibiting JNK activity.¹⁸
In Aβ-injected rats, NMN improved cognitive function, reduced neuronal cell death, and decreased oxidative stress.¹⁹
NMN reversed deficiencies in oxygen consumption and reduced levels of mutant APP in AD mice²⁰.

The most recent study, conducted by Fang et al. in 2019²¹, investigated the effects of NAD+ repletion on AD pathology using both animal models and human cell cultures.

The study found that NAD+ levels were significantly reduced in both the hippocampus and cerebral cortex of AD model mice. This depletion was associated with decreased activity of SIRT3, a NAD+-dependent deacetylase.

Restoring NAD+ levels through nicotinamide mononucleotide (NMN) administration:

Normalized NAD+ levels
Restored mitochondrial function
Reduced reactive oxygen species (ROS)
Decreased DNA damage
Improved neuroplasticity
Enhanced cognitive function in AD model mice

Nicotinamide Riboside (NR) vs Placebo

A study by Xie et al. published in Metabolic Brain Disease in 2019²² provides important evidence for the potential benefits of NR supplementation in Alzheimer’s disease and aging.

NR supplementation improved short-term spatial memory in aged mice and enhanced contextual fear memory in AD model mice.
NR inhibited the accumulation of amyloid-β (Aβ) in AD model mice and reduced the migration of astrocytes to Aβ plaques.
NR supplementation inhibited the activation of astrocytes in aged mice.
NR decreased the elevation of serum nicotinamide phosphoribosyltransferase (NAMPT) in aged mice, potentially indicating reduced inflammation.

Moreover, a 2020 review of the protective effects of NR against cognitive impairment²³ found that NR has shown the ability to:

Inhibit the accumulation of pathological hallmarks of Alzheimer’s disease
Improve learning and memory in various murine models for dementia
Reduce DNA damage, neuroinflammation, and apoptosis
Improve hippocampal synaptic plasticity in diabetic mice and an Alzheimer’s disease mouse model

The evidence paints an intriguing picture: declining NAD+ levels in brain cells appear to be a hallmark of aging and contribute significantly to the pathology of Alzheimer’s disease. Perhaps most exciting is the prospect that a simple, safe vitamin-based intervention could help protect our aging brains.

While more research is needed, the possibility of an accessible and affordable approach to neuroprotection offers hope in our ongoing fight against Alzheimer’s disease.

NAD Treatment Approaches

As we age and face increasing cognitive challenges, maintaining optimal NAD+ levels becomes an important piece of the puzzle for supporting brain health and potentially reducing the risk of Alzheimer’s and dementia. Here’s a look at two primary treatment approaches to optimizing your NAD+ levels for cognitive function and neuroprotection.

NAD IV Therapy

While NAD+ IV therapy has gained popularity in recent years, its efficacy in treating Alzheimer’s disease remains largely unproven. Current evidence is limited to a single case report where one patient showed subjective improvements in memory and overall attitude. It’s important to understand that NAD+ IV infusion primarily increases extracellular NAD+ levels, without necessarily improving intracellular concentrations where the molecule’s beneficial effects primarily occur.

Moreover, patients should be aware of potential side effects associated with NAD+ IV therapy. The invasive nature of IV administration and the lack of comprehensive clinical studies make this approach less favorable compared to other available options for supporting cognitive health.

NAD+ Precursor Compounds

In contrast to IV therapy, NAD+ precursor compounds have demonstrated substantial promise in scientific research, as detailed in our previous section. These compounds work by providing the building blocks your body needs to naturally increase cellular NAD+ levels, potentially supporting cognitive function and neurological health.

For those seeking an evidence-based solution to optimize their NAD+ levels, our NAD boosting supplement Vitality ↑® offers a clinically validated formulation that combines proven NAD precursors NMN and nicotinamide with D-ribose and creatine monohydrate.

This synergistic blend represents a significant advancement in NAD+ supplementation. The carefully selected ingredients work together to:

Enhance cellular NAD+ production
Support comprehensive cellular regeneration
Optimize energy metabolism
Promote cellular repair mechanisms

What sets Vitality ↑® NAD+ Booster apart is its superior efficacy compared to individual NAD+ precursors. Users consistently report notable improvements in their overall health and performance after achieving optimized NAD+ levels through this comprehensive formulation.

The clinical validation behind this unique combination of ingredients makes Vitality ↑® NAD+ Booster an excellent choice for individuals looking to support their cognitive health and potentially reduce their risk of age-related cognitive decline.

SHOP NAD+ BOOSTER

Testing NAD+ Levels to Prevent Cognitive Decline

An image of an old woman exercising her cognitive ability to prevent decline

Just as regular health screenings help detect various medical conditions early, monitoring your NAD+ levels provides valuable insights into your cellular health—particularly in regions critical for cognitive function.

Research has established that declining NAD+ levels correlate strongly with cognitive deterioration and increased risk of neurodegenerative conditions. Think of NAD+ as your cells’ essential energy currency—when levels drop, cellular functions begin to falter, potentially contributing to:

Reduced neural repair and maintenance
Decreased energy production in brain cells
Compromised DNA repair mechanisms
Impaired cellular stress response

Our Intracellular NAD® Test offers a precise measurement of NAD+ levels where it matters most—inside your cells. Unlike conventional testing methods that may only capture extracellular NAD+, our innovative approach provides:

Accurate measurement of cellular NAD+ concentrations
Comprehensive analysis of your metabolic health
Early detection of potential NAD+ deficiencies
Personalized insights for optimization strategies

Don’t wait until cognitive changes become apparent. Understanding and optimizing your NAD+ levels today could play a role in maintaining your cognitive health tomorrow. Begin your journey toward optimal brain health with the Intracellular NAD Test—your window into cellular wellness and cognitive longevity.

ORDER YOUR NAD TEST

Referenced Sources:

Revolutionizing America’s Health: My Journey and Shared Vision with RFK Jr.

Written by Jinfiniti Science on November 28, 2024. Posted in Obesity and Weight Gain, Guest Blog. No Comments on Revolutionizing America’s Health: My Journey and Shared Vision with RFK Jr.

America is facing a health crisis of epic proportions. Chronic diseases like obesity, diabetes, and heart disease have become the norm rather than the exception.

Our food system is flooded with ultra-processed, nutrient-devoid products, and the healthcare system focuses more on treating symptoms than addressing root causes.

For decades, I lived as both a victim of this broken system and an unwitting contributor to it. My journey—from battling obesity to pioneering solutions—led me to a revelation: we can, and must, Make America Healthy Again (MAHA).

What started as a personal battle turned into a movement, one that aligns closely with leaders like Robert F. Kennedy Jr., who dares to question the status quo of our healthcare and food systems.

RFK Jr. has famously spoken out about the inadequacies of medical practices and government policies, shedding light on the systemic failures that perpetuate poor health. I share his passion for truth and reform. Together, our shared mission is to empower Americans to reclaim their health—not through fads or gimmicks, but through education, real food, and science-backed solutions.

The Early Struggles: Living the Problem I Wanted to Solve

An image of Chuck Nix with his companion towards his advocacy

My name is Chuck Nix, and my journey to health advocacy has been a long road of personal struggle, revelation, and relentless perseverance. Born in Dallas, Texas, in 1959 and adopted at birth, I grew up in a household where processed and junk food reigned supreme.

Although my adoptive parents were normal weight, I quickly became one of those rare, chubby kids in my era. Food was comfort, habit, and, unknowingly, the root of my lifelong health challenges.

By ninth grade, I weighed 210 pounds at 5’9″ and was already struggling with my weight and the desire to fit in. I attempted my first “diet” then, starving myself to lose weight, but I was constantly hungry, and the weight just came back. This set off a decades-long cycle of yo-yo dieting, reaching extremes.

As an adult, standing at 6’2″, I hit a low of 160 pounds in 1985 through intense exercise and strict calorie restriction. But it was unsustainable—I was thin, not fit, and the weight eventually crept back on.

My weight was a constant battle—one that followed me through every phase of life. I tried calorie restriction, extreme exercise, and countless diets, all while following the outdated, low-fat, high-carb dietary advice of the time.

Over the years, my weight fluctuated wildly, reaching a high of 315 pounds in 2018. I nearly died that year. In my 20s and 30s, I tried everything I could think of: severe calorie restriction, sometimes eating only 1200 calories a day, paired with hours of exercise. But high-stress jobs and lack of time always led me back to quick meals at the drive-thru.

Every time I lost weight, I seemed to gain it back with a vengeance.

In 1991, I met my biological family, and what I saw was eye-opening: my biological mother’s side of the family was obese, with one of my half-brothers even reaching 465 pounds. It was a warning of what could have been me without discipline.

Around this time, I made a serious effort to get fit, following the low-fat advice of doctors, working out at two gyms, and jogging five miles daily. After six years of dedication, I’d only managed to get down to 240 pounds. I felt like a failure, but little did I know, I had been misled.

The turning point came in late 1999 when I discovered the Atkins Diet.

The initial “induction phase” was ketogenic, and in just 3.5 months, I lost 60 pounds with zero exercise. I felt fantastic for the first time in years and was determined to finally achieve the fit, healthy body I had chased for so long.

I hired a personal trainer, but he warned me that Atkins was dangerous and could destroy my liver and kidneys. Trusting his advice, I compromised, adding more carbs.

The result? I gained 40 pounds of fat and became re-addicted to carbs. I ended up suing the gym and got my money back, but I felt utterly defeated.

For decades, I believed I was failing, but in reality, the system was failing me.

Science now shows that the food pyramid we were taught to follow in the 1980s was built on flawed assumptions and industry influence. High-carb, low-fat diets were a recipe for insulin resistance, metabolic disorders, and cravings that kept us dependent on sugar-laden foods.

My health continued to spiral. By 2003, I’d made a career shift and finally achieved a dream of mine: founding my frozen dessert company, Silky Smooth Frozen Custard.

This was the first Wisconsin-style frozen custard shop in Beverly Hills, and later evolved into Silky Smooth MicroCreamery, which won “Best Ice Cream in LA” in 2007.

The shop attracted celebrities like Kim Kardashian and Tyra Banks, but it all came crashing down with the Great Recession in 2008. I lost everything—my business, my credit, my hope. From there, I hustled in the world of credit funding, eventually building up to a six-figure business. And then COVID hit, and it all crumbled once again.

The Breakthrough: Science Meets Personal Experience

In 2016, I stumbled across the show My Diet is Better Than Yours, which highlighted the ketogenic diet, helping a man in his late 50s lose significant weight.

I was angry—had I been lied to all those years? More research led me to Dr. Eric Berg, who taught me the truth about keto and intermittent fasting. I finally found an approach that worked for me, dropping 100 pounds in nine months with no exercise.

I felt decades younger, but more importantly, I felt in control for the first time. I learned that sugar was poison, and I became determined to help others find freedom from it.

Armed with this new knowledge, I decided to bring back my dessert brand as an all-keto operation. I spent years developing SilkySweet®, an all-natural, sugar-free sweetener that tasted better than cane sugar and cured my own sugar cravings.

SilkySweet® was originally created to replace the “forced by law” use of Sucralose in Silky Smooth frozen desserts, reformulating them to meet future Ketogenic Certified health standards. Through extensive R&D, we developed a formula superior to cane sugar, leading me to market it globally as the ultimate, realistic cure for sugar addiction.

I even created SilkySweet KetoCola, a sugar-free cola that was preferred three to one over Mexican Coca-Cola in taste tests. Despite my breakthroughs, COVID delayed production, inflation spiked, and my business struggled to take off. Personal credit was once again destroyed, and I faced setback after setback.

From Personal Mission to National Movement

In 2022, I had a moment of clarity: my mission was bigger than just selling products. I needed to help Americans break free from the toxic food system that was driving chronic disease and obesity.

Inspired, I initially came up with the concept of “Make America Healthy Again” (MAHA) and created a prototype purple hat to symbolize unity by merging red and blue.

However, I soon evolved the phrase to “Making America Healthy Again” and produced 500 hats.

The shift from “Make” to “Making” reflects a move from a campaign promise—set to expire on 11/5/24—to an active, ongoing mission of healing and curing, embodied by the world’s only realistic solution for sugar addiction: SilkySweet.com.

Like many breakthrough ideas that show up concurrently in different geographic areas and even cultures, this vision, MAHA, caught fire with movers and shakers, including Robert F. Kennedy Jr., long a champion of health reform.

The first purple MAHA hats symbolized my call for unity across all demographics and political divides, with red and blue merging into purple, a call for health transformation and healing in America.

In 2023 I took a gamble and exhibited at an anti-aging/health event. I caught the bug and got Longevity Fever.

I immersed myself in education and made contacts that have proven very beneficial for my MAHA movement. I had been taking an NAD+ supplement that was not working and discovered Jinfiniti Precision Medicine and their Vitality Boost NAD+ “Optimizer.” (The technical description of the product is actually NAD+ Booster supplement. These are the things you learn when you take the deep dives!)

Like so many other consumers who believe that all supplements are created equal, I got schooled in the importance of using data-driven, science-backed products, and in particular, the need to optimize my intracellular NAD.

I met Dr. Jin-Xiong She, Jinfiniti’s Founder and Chief Scientist.

Jinfiniti’s Special Projects Director, Greta Blackburn, was moderating a panel at the event and, upon hearing of my mission, introduced me to her panel member Dr. Robert Lufkin, author of “Lies I Taught In Medical School’ and a USC Professor. Dr. Lufkin and I shared so many common beliefs and he, like Dr. Eric Berg, who set me straight on Keto, are part of my semi-official Advisory Team as the mission moves forward.

Dr. Lufkin and I touched base only briefly at that ’23 event but at the same event the following year we had time to share some conversations and today I reach out to him regularly for his expertise and highly material insights for the MAHA cause.

In 2024, something remarkable happened. After switching to a full carnivore diet, I received life-changing blood test results and adjusted my macros to 80% fat.

Almost overnight, my vision, which had been compromised since I was a child, transformed. My eyesight returned sharper than ever—20/10 in both eyes—and I could see in 3D for the first time since childhood, all without the need for glasses or contact lense.

I knew then that my mission was not only to heal myself but to bring real health solutions to every American.

The RFK Jr. Connection: A Shared Vision for Health Reform

An image showing the advocacy to make America healthy again

In September 2024, I took MAHA to the Senate hearings in Washington, D.C., where I met Senator Ron Johnson, and Calley and Casey Means. Thanks to a friend who helped with travel costs, I witnessed firsthand the growing momentum for healthcare reform. I knew that MAHA was not just a vision but a movement with real potential to change lives.

It was recently announced that RFK Jr. is being appointed as the next Secretary of Health and Human Services. I am excited about the possibilities for my MAHA mission combined with his.

Sometimes we feel that our ideas, journeys, and trials and tribulations are all for naught. I’m here to tell you that we can all use our passion as fuel to make change. It takes work. It means sacrifice, but in the end, miracles can happen, relationships can be forged, and change can happen.

Today, I work alongside pioneers like Dr. Jin-Xiong She, who introduced me to Jinfiniti’s anti-aging supplements, and Greta Blackburn- formerly known as The Telomere Diva for her part in the launch of TA Sciences, and for her role in developing and co-writing the layman’s book on telomeres, “The Immortality Edge”– who immediately saw the potential in MAHA.

Greta now calls herself a NAD Nerd and a MAHA Mafiosa!

Together, we’re pushing forward with the vision to Make America Healthy Again, one taste bud and one American at a time.

My journey has been filled with struggles, but each one has brought me closer to this mission. As I stand here today, with my iconic purple MAHA hat and years of hard-earned wisdom, I’m more committed than ever to making this vision a reality.

NAD Levels by Age Group: What’s Considered Normal?

Written by Jinfiniti Science on November 12, 2024. Posted in NAD+, NAD, NAD+ Precursors, Premature Aging. No Comments on NAD Levels by Age Group: What’s Considered Normal?

Your body is a vast metropolis, with billions of cells working around the clock to keep you alive and thriving. At the heart of this cellular city lies NAD+ ( short for nicotinamide adenine dinucleotide) – the power currency that keeps your cellular economy from entering a recession.

Just as a city needs electricity to function, every cell in your body needs NAD+ to convert food into energy, repair damaged DNA, and regulate your biological clock. This coenzyme helps your cells perform over 500 different biochemical reactions, making it one of the most important players in healthy aging and overall wellness.

Unfortunately, our bodies’ levels of NAD naturally decline as we age, dropping by up to 50% between our 20s and 80s. This decline is linked to many of the telltale signs of aging, from decreased energy levels to slower recovery after exercise. Understanding what’s “normal” for NAD+ levels at different ages can help us better grasp why we feel the way we do as time passes, and potentially, what we can do about it.

What You Should Know

NAD+ levels drop by 40-50% between your 20s and age 50, contributing to fatigue, slower recovery, and increased disease risk.
Optimal NAD+ levels fall between 40-100μM, with anything below 40μM considered suboptimal or deficient.
Men typically have higher baseline NAD+ levels than women, but experience steeper declines after age 60.
Lifestyle changes like exercise and diet may not fully counter age-related NAD+ decline, making targeted supplementation necessary for optimal levels.

NAD+ and Aging

Middle-aged couple holding hands by the lake

Your body’s NAD+ levels follow a predictable pattern throughout life – and unfortunately, it’s a downward trend. Research shows that NAD+ levels peak during our early 20s and then begin a steady decline, with most people experiencing a 40-50% drop by age 50. But why does this happen? The answer lies in a perfect storm of biological events.

As we age, certain enzymes, particularly PARPs and CD38, become increasingly active and hungry for NAD+¹. PARPs ramp up their activity to repair age-related DNA damage, while CD38 levels rise as part of our body’s inflammatory response to aging. It’s like having more bills to pay but with the same paycheck – something has to give.

At the same time, our body’s ability to produce new NAD+ takes a hit. The molecular building blocks (or precursors) that we use to make NAD+ become less available, and the cellular machinery (biosynthetic enzymes) that assembles these pieces slows down². It’s similar to a factory facing both parts shortages and aging equipment – production inevitably drops.

This decline in NAD+ levels has real consequences for how we age. When cells can’t maintain healthy NAD+ levels, their energy production falters, DNA repair slows down, and cellular stress responses become sluggish. These changes contribute to many hallmarks of aging, from decreased muscle strength and slower wound healing to increased susceptibility to age-related diseases like cardiovascular problems and neurodegenerative conditions.

The Timeline of NAD+ Decline

Visual gif chart of NAD+ levels decline by age group

Infancy & Childhood (0-12 years)

NAD+ levels are naturally high and stable
Peak production supports rapid growth and development

Adolescence & Young Adulthood (13-30 years)

Levels reach their lifetime peak in early 20s
Optimal cellular energy and repair functions
Gradual decline begins around age 25

Middle Age (31-60 years)

Sharp decline begins
Most dramatic drop occurs between 40-49 years³
Average person loses 40-50% of young adult levels by age 50

Senior Years (60+ years)

Levels can drop to 1-10% of youthful amounts
By age 80, typical levels are less than half those at age 40
Continued gradual decline without intervention

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What are Normal NAD Levels by Age Group?

Inside our cells, NAD concentrations can range from as low as 10 μM to as high as 1000 μM⁴. To put this in perspective, imagine filling a drop of water with different amounts of NAD – some cells maintain just a trace amount, while others keep a abundant supply, depending on their specific energy needs. When measured in tissue samples, researchers have found total NAD concentrations between 0.3 and 0.4 μmol/g.

Based on Dr. Jin-Xiong She’s clinical research, we now have clear benchmarks for interpreting intracellular NAD levels:

Severely deficient: 0-20μM
Deficient: 20-30μM
Suboptimal: 30-40μM
Optimal: 40-100μM
Too high: Above 100μM (may not provide additional benefits and could potentially be harmful)

These optimal ranges of 40-100μM are the sweet spot where NAD-dependent enzymes, including sirtuins and PARPs, can function most effectively.

Tissue-Specific NAD+ Decline

Rodent Studies

Human Studies

Skeletal Muscle

15-65% Decline

Consistent decrease with age in rodents, particularly in the gastrocnemius muscle.

Liver Tissue

10-50% Decline

Variable patterns with age. Most studies report decline in aged rodents with some exceptions.

Cardiac Tissue

0-65% Decline

Highly variable pattern. Study differences likely reflect species, strains, and methodological approaches.

Brain Regions

Variable by Region

Declines earlier than other tissues. Different brain regions show distinct patterns.

Skin Tissue

≥50% Decline

Substantial reductions with age. Strong negative correlations between NAD+ levels and age in both genders.

Brain & Cerebrospinal Fluid

10-25% Decline

Approximately 14% decrease in subjects older than 45 years compared to younger subjects.

Blood NAD+ Levels

Decline before age 50

More pronounced decline in men than women, especially in middle age (40-49 years).

Measuring Your NAD Levels

Clinical evidence suggests that suboptimal NAD levels may contribute to various health challenges – from chronic fatigue and sleep disturbances to cognitive decline and metabolic disorders.

Modern methods like Jinfiniti’s Intracellular NAD Test now allow for precise measurement of cellular NAD concentrations through convenient at-home collection, enabling individuals to assess their personal NAD status and work to optimize their levels and address NAD deficiency symptoms through targeted interventions.

The Gender Gap in Age-Specific NAD+ Levels

Studies have consistently shown that men tend to have higher baseline levels of whole blood NAD+ compared to women. In one large-scale study of over 1,500 participants, the average NAD+ level in men was 34.5 μmol/L, while women averaged 31.3 μmol/L⁵.

However, the way NAD+ levels change with age differs significantly between the sexes:

In men, NAD+ levels tend to decline gradually with age, with a more pronounced drop observed after age 60
Women, on the other hand, show a more complex pattern. Their NAD+ levels fluctuate across age groups without a clear downward trend

The distinct NAD+ profiles between men and women suggest that hormones play a role in regulating NAD+ metabolism. Researchers speculate that female sex hormones, particularly estrogen, may help maintain NAD+ levels throughout a woman’s life. This hypothesis is supported by observations in post-menopausal women, whose NAD+ patterns begin to resemble those of men.

The gender gap in NAD+ levels and their age-related changes may have far-reaching implications for how men and women age:

Higher NAD+ levels in men might provide them with a metabolic advantage in youth, but the steeper decline with age could contribute to accelerated aging in some aspects.
The more stable NAD+ levels in women could potentially offer some protection against certain age-related diseases, though more research is needed to confirm this.
The effectiveness of NAD+ boosting supplements or therapies may differ between men and women, necessitating gender-specific approaches to anti-aging treatments⁶.

Strategies for Increasing NAD+ Levels as You Age

While many people seek to naturally increase NAD levels through lifestyle modifications like exercise, intermittent fasting, and consuming NAD-rich foods, research shows these methods alone can’t fully counter age-related NAD+ decline. It’s like trying to fill a leaking bucket – as we age, our cells’ increasing demand for NAD+ outpaces what we can restore through lifestyle changes alone.

A more comprehensive approach involves strategic supplementation with NAD boosters that target the root cause of age-related NAD+ decline. The key lies in providing your body with the right precursors in the right combinations to optimize NAD+ production at the cellular level.

Recent clinical research has revealed that a synergistic approach yields better results than single-compound solutions. This breakthrough understanding led to the development of Vitality ↑® NAD+ Booster, Jinfiniti’s scientifically formulated combination of NMN, Creatine monohydrate, D-Ribose, and Nicotinamide. Each component plays a crucial role:

NMN serves as a direct NAD+ precursor
Creatine monohydrate supports energy metabolism
D-Ribose enhances cellular energy production
Nicotinamide helps regulate NAD+ consumption

What sets this formulation apart is its extensive validation – from clinical studies to real-world testing in hundreds of clinics. The data speaks for itself: approximately 85% of users achieve optimized NAD+ levels, as confirmed through clinical testing. This high success rate demonstrates that while aging’s effects on NAD+ levels are inevitable, they’re not irreversible.

Think of maintaining healthy NAD+ levels as a long-term investment in your cellular health. While lifestyle factors provide the foundation, targeted supplementation with clinically validated NAD boosters offers the most reliable way to maintain optimal NAD+ levels as you age. The key is choosing a solution backed by both scientific research and real-world results.

Referenced Sources

NAD Deficiency Symptoms: 6 Common Signs of Low NAD Levels

Written by Jinfiniti Science on October 28, 2024. Posted in NAD+, Depression and Anxiety, Energy and Fatigue, Memory Loss and Brain Fog, NAD, Skin Health, Sleep. No Comments on NAD Deficiency Symptoms: 6 Common Signs of Low NAD Levels

Feeling sluggish, mentally foggy, or struggling to keep up with your routine lately?

While it’s quite normal to feel this way from time to time, you shouldn’t take these frustrating signs for granted.

What seems like just another bad day could be a telltale sign that your NAD+ levels are running low.

Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme that plays a critical role in energy production, DNA repair, and overall health.

Unfortunately, NAD+ levels naturally decline with age and can be further affected by lifestyle factors, leading to a range of symptoms that are often overlooked.

So, what are these warning signs, and how can you optimize your NAD+ levels to stay healthy and active as you age?

In this article, we discuss:

Why your NAD levels are dropping faster than you think—and it’s not just because you’re getting older.

7 subtle signs of NAD deficiency that many people dismiss as “just part of aging,” but shouldn’t.

The red flags of severe NAD deficiency you can’t afford to ignore.

How to accurately detect low NAD levels in your body and the easiest, most effective ways to boost them naturally.

Understanding NAD+ and Why It Declines

Nicotinamide adenine dinucleotide, or NAD+, is an essential coenzyme found in every cell of our body. It plays a key role in several critical processes, including energy metabolism, DNA repair, and cellular signaling.¹

Essentially, NAD+ acts like a shuttle for electrons during metabolic reactions, helping to transform the food we consume into usable energy and supporting the production of ATP, which is the main energy currency for our cells.

Beyond just energy production, NAD+ also maintains the integrity of our DNA and regulates various cellular functions that keep us healthy.

Unfortunately, by the time we reach our 30s, our NAD+ levels start to decline. In fact, NAD+ can decrease by up to 50% as we age,² with noticeable reductions in the skin and other tissues.

This decline can be accelerated by factors like oxidative stress,³ unhealthy diets, and lifestyle choices, leading to symptoms that are often mistaken for the typical signs of aging.

But in reality, these may be early signs of low NAD+ levels, indicating that it’s time to take action and make necessary lifestyle changes to support your health and longevity.

Common Symptoms of NAD+ Deficiency

Below are six common health symptoms that indicate you may be deficient in NAD.

Fatigue and Low Energy

NAD is essential for energy metabolism. Think of it as the engine that powers your body, helping convert the food you eat into usable energy. However, when your NAD+ levels drop, it can disrupt your metabolism and may result in fatigue and low energy.

Your body might also struggle to produce ATP (adenosine triphosphate), which is your main source of energy. The result? You might feel sluggish and worn out. NAD+ also supports the proper functioning of enzymes that protect against oxidative damage.

When these protective enzymes can’t do their job because of low NAD levels, it creates an imbalance between harmful reactive oxygen species and protective antioxidants⁴ that can further drain your energy and leave you feeling even more fatigued.

Moreover, NAD+ is important in metabolizing carbohydrates, fats, and proteins. When your NAD+ levels are low, these metabolic pathways can become inefficient, leading to even more tiredness. For instance, if your body can’t break down fatty acids properly, it can accumulate unused substrates that sap your energy.

Not to mention, during physical activity, your muscles depend heavily on NAD+ for energy.⁵ If you’re low on NAD+, you might experience muscle weakness and decreased endurance, making even simple tasks feel much more challenging.

Cognitive Symptoms

NAD is also important for maintaining healthy cognitive function. When your levels drop, you might start to notice some cognitive symptoms, such as mental fog, memory lapses, and a general decline in sharpness.

This is because NAD+ is crucial for energy metabolism and mitochondrial function, both of which are essential for your brain to perform at its best. When NAD+ levels are low, the brain struggles to produce adenosine triphosphate (ATP)⁶—the energy that powers our cells—leading to sluggish thinking and that frustrating feeling of mental cloudiness or fatigue.

Research shows that a deficiency in NAD+ can worsen neuroinflammation and oxidative stress, both of which are harmful to cognitive health, potentially leading to increased neuronal damage and cognitive issues,⁷ such as forgetfulness and decreased mental agility.

Skin and Appearance Changes

Is your skin looking dry and dull despite your diligent skincare routine and healthy lifestyle? One hidden culprit could be low NAD+ levels.

Research shows that low NAD+ levels can hinder your skin’s ability to repair itself, particularly from damage caused by sun exposure. This impairment can result in more visible signs of aging, such as wrinkles and loss of elasticity.

Additionally, because NAD+ plays a key role in supporting mitochondrial function—the process that provides the energy your skin cells need to regenerate and stay vibrant⁸—low NAD+ levels can impede cell renewal. This leaves your skin looking tired, dull, and less radiant.

Poor Sleep Quality

Having trouble getting a restful night’s sleep? It could be more than just stress or a racing mind—it might actually be a deficiency in NAD+ levels.

As a coenzyme, NAD+ supports energy production and maintains healthy cells, including those involved in regulating your sleep cycle. When NAD+ levels decline, especially as we age, this drop can disrupt your sleep patterns.

Since NAD+ helps regulate key “clock” genes that control your sleep-wake cycle, it can throw off your body’s internal clock, or circadian rhythm,⁹ making it harder to fall asleep or stay asleep through the night.

Research also reported that NAD+ is essential for the synthesis of serotonin from tryptophan, a precursor amino acid.¹⁰ If NAD+ levels drop, this metabolic pathway can become inefficient, potentially leading to reduced serotonin and subsequently lower melatonin levels.

Therefore, you may experience sleep disturbances and increased fatigue due to inadequate melatonin production.

Mental Health and Mood Swings

Low NAD+ levels can significantly affect your mood and mental health, often manifesting as mood swings, irritability, anxiety, or even depression.

This occurs because NAD+ deficiency disrupts the balance of crucial neurotransmitters like serotonin, dopamine, and norepinephrine,¹¹ which are essential for regulating mood and emotional responses. As a result, you may experience persistent feelings of anxiety or sadness.

NAD+ is also important in activating sirtuins—proteins that help cells manage stress.¹² When NAD+ levels are low, sirtuins become less effective, which can contribute to mental health challenges like anxiety and irritability.

This makes it harder for your brain to cope with stress, intensifying emotional imbalances.

Metabolic Health Issues

NAD+ deficiency can lead to various metabolic problems,¹³ including weight gain, insulin resistance, and a higher risk of metabolic disorders.

NAD+ underpins key metabolic processes like glycolysis, the TCA cycle, and oxidative phosphorylation. When NAD+ levels drop, these processes become less efficient, disrupting energy metabolism and contributing to issues such as weight gain and insulin resistance.

Low NAD+ also affects enzymes involved in energy production, leading to reduced ATP synthesis and increased fat storage, particularly in the liver and fat tissue. This buildup of fat triggers inflammation, further worsening insulin resistance.

Moreover, NAD+ activates sirtuins, proteins that help regulate glucose and fat metabolism. When NAD+ levels are low, sirtuin activity declines, making it harder for the body to control blood sugar and insulin sensitivity,¹⁴ which raises the risk of type 2 diabetes.

People with low NAD+ levels are also more prone to developing metabolic conditions like diabetes and non-alcoholic fatty liver disease (NAFLD).

Severe NAD+ Deficiency Symptoms

People with NAD+ deficiency may also experience severe symptoms similar to pellagra, a condition caused by niacin deficiency.¹⁵

These symptoms indicate a critical lack of NAD+.

Dermatitis typically manifests as a scaly rash that worsens with sun exposure, indicating the body’s diminished capacity for healing due to low NAD+ levels. Diarrhea stems from impaired gut function and disrupted metabolism, which can lead to dehydration and poor nutrient absorption. Cognitive issues like memory loss and confusion arise because NAD+ is integral for brain cell energy production and neuronal health.

If left untreated, NAD+ deficiency can result in severe metabolic dysfunction,¹⁶ increasing the risk of serious conditions such as cardiovascular disease, diabetes, neurodegenerative disorders, and even death.

Cardiovascular Impact of NAD+ Deficiency

Low NAD+ levels can greatly increase the risk of cardiovascular diseases,¹⁷ hypertension, and reduced heart function. When NAD+ levels decline, vital processes like energy metabolism, DNA repair, and oxidative stress management become compromised, leading to a range of cardiovascular issues, especially hypertension.

Research published in the Signal Transduction and Targeted Therapy shows that hypertensive patients have a 44% lower NAD+ level in their peripheral blood mononuclear cells¹⁸ compared to those with normal blood pressure. This reduction is closely linked to impaired vascular function and elevated arterial pressure.

Additionally, NAD+ deficiency can cause mitochondrial dysfunction, which is crucial for maintaining cardiac energy metabolism.¹⁹ This leads to reduced ATP production and increased oxidative stress, both of which contribute to heart failure and other cardiovascular problems.

The enzyme CD38, which depletes NAD+, is often overactive in hypertensive individuals, further draining NAD+ levels and negatively affecting vascular health and heart function.

Beyond hypertension and weakened heart function, chronically low NAD+ levels can increase the risk of severe cardiovascular diseases like atherosclerosis and coronary artery disease,²⁰ which, if not addressed, can result in life-threatening events such as heart attacks and strokes.

NAD+ Deficiency in Specific Populations

While it’s common knowledge that NAD+ levels decline after the age of 30, certain groups are at a higher risk of experiencing a deficiency.

Obese individuals, for example, tend to have significantly lower NAD+ levels²¹ than those with a healthy weight. This is because excess fat triggers chronic inflammation and metabolic imbalances, which further deplete NAD+ levels.

Obesity is also associated with impaired NAD+ metabolism, increasing insulin resistance,²² and elevating the risk of type 2 diabetes and related conditions.

Genetic disorders also contribute to NAD+ deficiency risk. Individuals with conditions like congenital NAD deficiency disorder (CNDD)²³ experience inadequate NAD+ production, leading to developmental abnormalities and other health complications.

Genetic mutations that interfere with enzymes responsible for NAD+ synthesis reduce the availability of this vital coenzyme, contributing to congenital defects and increased health risks.

Given all these factors, the important question is: Are you NAD+ deficient? The only way to find out is to test.

How to Test if Your NAD Levels Are Low

Now that you understand the signs of NAD deficiency, how do you find out if your NAD levels are truly suboptimal?

At Jinfiniti, we prioritize precision over guesswork. That’s why we recommend the most reliable approach: testing your NAD+ levels directly.

Our Intracellular NAD Test gives you a clear picture of what’s happening inside your cells. We measure your actual NAD+ levels to help you see where you stand – whether they’re running low, sitting at a healthy baseline, or higher than average. With these insights, you can make smarter decisions about your NAD+ supplements and know if they’re really working for you.

TEST YOUR NAD LEVELS TODAY

How to Treat Low NAD Levels

If you suspect your NAD+ levels are low or have confirmed a deficiency through testing, there are several evidence-based approaches to increase your NAD+ levels naturally and through supplementation. The key is finding the right combination of lifestyle modifications and targeted support for your individual needs.

Research shows that regular exercise, particularly high-intensity training, naturally boosts NAD+ production. Combining this with a diet rich in B3 vitamins and stress management techniques can help optimize your body’s NAD+ levels while preventing excessive depletion of existing stores.

For those seeking intensive support, medical NAD+ therapies like IV infusions are available at specialized clinics. While these treatments can rapidly elevate extracellular NAD+ levels, they are costly and may cause side effects like flushing and headaches, requiring close medical supervision.

A more accessible and scientifically-validated approach is supplementation with NAD+ precursors.

Our High Purity NAD+ Precursor powder offers a premium-grade, pure form of NAD+ as a building block that your body can efficiently convert into active NAD+.

For those seeking enhanced results, our breakthrough Vitality ↑® NAD+ Booster takes supplementation to the next level by combining a clinically proven NAD+ precursor with synergistic ingredients. The strategic inclusion of creatine monohydrate helps stabilize cellular energy systems, while D-ribose and nicotinamide work together to optimize NAD+ synthesis pathways.

This unique formulation has been shown to increase NAD+ levels more effectively than single-ingredient supplements, providing total support for your cellular health and energy production.

With these strategies in hand, you’ll be on the right track to treating NAD deficiency and promoting longevity.

SHOP NAD+ SOLUTIONS

Referenced Sources:

True Story: Dementia-Related Memory Loss Restored 50% OVERNIGHT

Written by Jinfiniti Science on September 2, 2024. Posted in NAD+, Memory Loss and Brain Fog, NAD, Neurological Diseases, Popular. No Comments on True Story: Dementia-Related Memory Loss Restored 50% OVERNIGHT

Dementia is a serious condition that affects over 55 million people worldwide, with nearly 10 million new cases each year¹.

The impact of dementia goes far beyond the person who is diagnosed; it also deeply affects their families, who struggle with the emotional and mental pain of seeing their loved ones’ memories fade away.

Watching someone you care about lose the ability to do everyday things, forget important moments, or fail to recognize familiar faces can be incredibly hard.

Families often feel helpless and overwhelmed, desperately searching for ways to restore what has been lost.

But there is hope.

Take Marshall, a 94-year-old who completely forgot how to use his phone and computer after being diagnosed with dementia.

After just one night of using Vitality NAD+ Booster, a supplement that contains nicotinamide adenine dinucleotide (NAD) precursors, Marshall’s memory began to improve, and he started to feel more like himself again.

SHOP NAD+ BOOSTER

His story shows that it’s possible to regain lost memories and improve mental clarity.

We hope that you or your loved ones can also benefit from optimizing your NAD+ levels.

Read Marshall’s story below.

I’m not sure what I expected, but…

I was surprised when my dear friend’s cognition declined dramatically overnight at age 94.

Sure, there had been some memory lapses over the course of his 93^rd year.

He occasionally forgot his house keys when he went out. He didn’t always remember everything he had driven to the grocery store to buy. (Yes, he was still driving safely at age 92 and beyond.)

Those lapses were the kind that everyone I know over the age of 40 has complained about, myself included.

Still, the signs of Marshall’s cognitive decline did not progress over the course of weeks or months, as I had believed they would, were they to happen at all.

I had hoped that he was past some imaginary statistical cutoff date by which I had presumed dementia would happen. I had read somewhere that by the age of 80, 1 in 6 people experienced some degree of dementia.

When my dear friend reached and passed his 90^th birthday with a mind sharp as a tack I assumed he was all clear.

By the time he celebrated his 94^th birthday, I relished the fact that he remembered things better than many 40-year-olds and he still “figured stuff out” (his phrase) really well for a person of any age.

Give him a problem to solve and if he hadn’t done so by day’s end, he would always spring out of bed the next day declaring, “I’ve got it!” having solved the problem throughout the night.

Marshall’s great mind and good memory were perfectly intact until one fateful day.

That day I discovered him sitting on his bed staring quizzically at his phone.

I asked him, “What are you doing, M?” He looked at me, bewildered, and replied, “I don’t know.”

I pressed him further. “What do you mean, ‘You don’t know’? Are you trying to call someone on your phone?” I asked.

“I’m trying to figure that out,” he told me. “I’m working on it.”

His words weren’t making sense to me. Working on what? What did he mean?

“Marshall,” I began, worried, “What do you mean ‘working on it”? What’s to work on? Just make the call if that’s what you’re trying to do.”

He looked at me with a blank expression and replied, “I don’t know how.”

I flashed back to years earlier when a very beloved actor friend of mine had called me at my apartment in New York City. He was talking to me in disconnected, somewhat incoherent phrases that I couldn’t understand.

Clearly, something was wrong.

I asked him where he was and he somehow managed to tell me with words that made some sense that he was at the nearby Apple Store.

I told him to stay where he was, that I would be right over. I quickly threw on a jacket and ran the four blocks to the store.

I found my friend sitting at a display bench downstairs in the store with an Apple clerk who seemed concerned.

My friend was insisting that she sell him a new iPhone, which she explained to me she didn’t want to do because his current model phone was working just fine.

I told her to cancel the order, which she didn’t want to place anyway.

I asked him a few questions, which he answered only somewhat coherently.

I apologized to the salesgirl and walked my friend out of the store. I found a bench where he could sit comfortably while I called his family at their home.

They were understandably concerned when I told them about his condition.

They were in another state but together we made the decision that I should get him to the nearest Urgent Care.

The staff there quickly diagnosed a suspected stroke and, with their help, I hastily got my friend to a nearby hospital.

He spent a week in the hospital and recovered, but things could have gone in a whole other direction had I not jumped into action when I did.

Was Marshall suffering the effects of a stroke? I determined to keep a close eye on him throughout that entire day.

I observed him sitting and staring into space from time to time, as though lost in thought.

When I asked him what he was thinking about, he said, “I’m figuring something out,” and he would return to gazing off into the distance with a vacant stare.

Later that day I discovered him sitting at his computer, staring at the screen, immobile.

“What are you doing, Marshall?” I asked him.

“I don’t know. I can’t answer that,” he said, clearly frustrated and confounded.

From one day to the next my friend had forgotten how to use both his cellphone and his computer.

Worse, he seemed “not all there” mentally.

There’s more but I won’t go into the details, which included some bathroom and basic walking issues. Suffice it to say he had devolved significantly over just 24 hours.

Over the next weeks, I took my friend from doctor to specialist to lab to ascertain exactly what was going on.

A brain MRI (not fun for him at all) ruled out any suspected brain mass/tumor but…

A battery of cognitive tests with a gerontology professional confirmed that he was experiencing mild to moderate dementia.

Watching him take that cognition test was painful because questions that he would have aced just the week before gave him great difficulty in answering.

He couldn’t even begin to draw the clock face requested in the test.

A former whiz with numbers, he was stumped when asked to count back from 100 in 7’s. (100, 93, 86, etc.) His frustration turned to anger and eventually, he refused to participate in completing the test.

Once home, I was shocked to discover that Marshall had completely mixed up his daily meds.

As a forever health freak and gym rat, he had always been compliant and rigorous with taking vitamins and the few prescriptions he was on.

He had gone on his first prescription meds just a few years before when diagnosed with non-small-cell lung cancer.

He was doing ok with that disease, given his age and the severity of such a condition.

The health equity he had built up over decades of clean, healthy living stood him in good stead to do battle with cancer.

He never missed a prescribed dose of anything the oncologist ordered and his vitamin game was strong after years of taking a full regimen of fitness and bodybuilder supplements.

However, a review of his medicine cabinet that day showed that things had gone very awry.

Some bottles that I knew should be there were missing and others contained far too many pills than they should have since the date of fulfillment at the pharmacy.

When I asked him if he had been taking his pills regularly, as he had always done, he looked at me with that new vacant, uncomprehending stare.

I took possession of all bottles from his bathroom shelf and called all of his prescribing doctors to review his treatment plan and get him back on track.

I took over the administration of meds and supplements. I felt lucky to have discovered the issue when I did.

Fortunately, doing some math on the bottles and the number of pills inside them proved that the pill problem had occurred concurrently with the cellphone and computer problem. Suddenly and recently.

With a heavy heart, I booked tours of Assisted Living homes in advance of what I was sure would soon be the need for 24/7 memory care.

And then I had a thought.

What if Vitality NAD+ Booster, a NAD supplement formula and known neurotransmitter, could help?

It is a favorite of mine and so many others for energy mental clarity and more. Why not give it a try?

That night I gave Marshall his first dose of the clinically-proven powder. The next morning? Nothing short of a medical miracle.

I could kick myself for not having recorded the “before” Vitality NAD+ Booster Marshall to the man who woke up that next day.

When I claim a 50% improvement in his cognition OVERNIGHT it sounds preposterous even to me!

Except I witnessed it. I continue to see it daily.

Has he suddenly regained 100% of his memory and ability to solve problems and think clearly?

Most definitely not. He is, however…

At least 50-65% cognitively recovered.

He knows how to use his phone, he’s back at the computer, those bathroom issues are pretty much gone, and he’s using his walker and cane as well as he formerly had.

He is now back in charge of his meds and supplements because he began to remind me to give him doses as he remembered what to take and when.

I check daily to make sure he has not forgotten anything, of course, but so far, so good.

I do mix up his Vitality NAD+ Booster for him and give him two scoops daily.

When he sees me coming with it, his eyes light up and he says, “Dr. She’s stuff?” and I shake my head “yes” in acknowledgment.

I think he looks forward to it because he knows the good it does him.

During a doctor visit with his Primary Care Physician yesterday, the doctor acknowledged the improvement he saw in Marshall.

I told him what I had added to the program and he said, “Well great, there is good data on that supplement.”

He’s one of the physicians I had taken Marshall to see to evaluate the sudden mental decline.

He’s the same doctor who had told me back then several months ago that Marshall could not be left alone anymore.

“If he can’t use his phone and he gets in trouble, it’s a big problem,” he advised.

Plus, he mentioned the stove incident that had happened during that awful week:

Marshall had turned on a gas burner that didn’t light and some gas fumes escaped before I noticed what was happening.

I’m grateful for however many months, hopefully, even years, that this product will enable my dear friend to enjoy his mind and his memory.

If it stopped working tomorrow, I would still be grateful today for the past six weeks of improvement.

Dementia moves in and makes itself at home with all too many families today. It’s a significant global health challenge.

Here are some key statistics highlighting the fact that it’s not “if” it’s “when” a friend, neighbor, work colleague, or family member of yours may experience this heartbreaking condition:

Global Prevalence: As of 2023, more than 55 million people worldwide are living with dementia. This number is expected to nearly triple by 2050, reaching 139 million due to aging populations.

Incidence: Around 10 million new cases of dementia are diagnosed each year. That equates to one new case every 3 seconds.

Age Factor: Dementia primarily affects older adults. About 1 in 6 people over the age of 80 have dementia. However, early-onset dementia, which occurs before the age of 65, accounts for about 9% of cases.

Economic Impact: The global cost of dementia is estimated to be over $1 trillion annually, including healthcare costs, informal care, and loss of productivity. This figure is projected to increase significantly in the coming decades.
Mortality: Dementia is one of the leading causes of death worldwide. In many countries, it ranks as the second or third leading cause of death among older adults.

Gender Disparity: Women are disproportionately affected by dementia. Approximately two-thirds of people with dementia are women, partly because women tend to live longer than men.

Alzheimer’s Disease: Alzheimer’s disease is the most common form of dementia, accounting for 60-70% of all cases.

These statistics underscore the importance of research, prevention, and support for those affected by dementia.

For those dealing with this problem, knowing that there’s a supplement that might, just might, mitigate some of the memory loss, should be welcome news.

In my opinion, Vitality NAD+ Booster is worth a try.

SHOP NAD+ BOOSTER

Referenced Sources:

https://www.who.int/news-room/fact-sheets/detail/dementia ↩︎

Is NAD a Healthy Weight-Loss Alternative to Ozempic?

Written by Jinfiniti Science on August 13, 2024. Posted in NAD, NAD+, Obesity and Weight Gain.

NAD+ overcomes insulin resistance without disastrous side effects.

Social media is burning up with images of celebrities who’ve dropped significant tonnage, but are mute about their methods.

This is an odd phenomenon, given the characteristic eagerness of this class to publicly pledge their allegiance to the newest fad, no matter how bizarre that craze might seem to the average person on the street. Yet, at each exhibition of luminary lipid loss, the same word is uttered in hushed whispers: Ozempic.

And we have to wonder, why the muted tones? If Ozempic is a miracle weight-loss drug, shouldn’t we be shouting about it from the rooftops? Turns out there are ample reasons to be wary, and even more reasons to choose a particular safe and effective alternative: the natural coenzyme NAD.

Step 1: Design a catchy ad campaign

Want to charge $1,200 a month for an injection whose benefits are decidedly short-term, and which puts patients at risk for numerous painful, debilitating side-effects, as well as a dispiriting rebound of the conditions they sought to alleviate in the first place? Then you must, must, must pick a catchy, long-forgotten pop song from the 1970s, whose original lyrics were all about the wondrous state of being in love.

Now you’ve got “Oh-oh-oh-Ozempic!” subliminally telling viewers of ubiquitous pharma commercials that “It’s magic.” Fossils of my era will remember the Scottish band Pilot cautioning listeners, “Never believe it’s not so!” But should we believe the advertising hype around Ozempic? Many sources, including those in the health and fitness sphere outside of Big Pharma, are telling us “No.”

What is Ozempic and why should I be skeptical?

According to the website Health.com¹, Ozempic a semaglutide, a “synthetic version of a human hormone called glucagon-like peptide one, or GLP-1.” Humans secrete GLP-1 when food reaches our gut.

It tells our brain that we’re full and tells our pancreas to get off the schneid and produce some insulin, the hormone that signals our cells to open wide and receive blood glucose.

When all works well, GLP-1 ensures that we don’t gorge ourselves and that the vacuoles of our cells widen, taking in glucose to convert to energy. This latter process also lowers our blood glucose levels, sparing us the consequences of diabetically high blood sugar.

People with type II diabetes either don’t produce enough insulin or suffer from extreme insulin resistance, so that while their insulin’s a knockin’, their vacuoles are sayin’ “Don’t come in.” (This is a problem with cell-signaling, one of the many cellular functions that depend heavily on the co-enzyme nicotinamide adenine dinucleotide, or NAD.)

Ozempic is designed to increase insulin production for type II diabetics who have had trouble getting their blood sugar under control with other methods. Ozempic is delivered via twice-monthly injections, at a cost of about $1,200 per month.

Health.com tells us, “After injection, semaglutide increases insulin production and lowers blood sugar. This causes the stomach to empty more slowly, reduces appetite, and makes people feel full.” So, it should come as no surprise that Ozempic has delivered another sought-after benefit: weight loss.

Is the bonus benefit just a dangerous illusion?

The Ozempic bonus has led overweight people, especially celebrities who can afford the high price tag, to request the drug for weight loss, a use for which the FDA has not approved it.

Yet, doctors seem willing to prescribe Ozempic for off-label use, a practice that is often controversial if not illegal. In fairness to these doctors, we should note that another semaglutide prescription, Wegovy, has FDA approval as a weight-loss drug. But should either of these synthetic hormone drugs be used for this purpose?

This lady in a lab coat says no. And we must listen because she is appropriately dressed. (Also note that she’s an MD, not an actress.)

Thank you, Dr. Annette Bosworth.

A litany of side-effects, some of which are deadly

If you’ve seen an O-O-O-Ozempic commercial, you’ve heard the recitation of side effects, which range from unpleasant to deadly. The mild variety includes:

Fatigue
Dizziness or vertigo
Discomfort and/or skin discoloration around the injection site
Increased heart rate
Changes in perception of taste
Digestive problems, such as belly pain, constipation, diarrhea, flatulence, burping, nausea, and vomiting

Ozempic patients have also started reporting hair loss².

The more serious side effects include:

Kidney problems, such as kidney failure
Low blood sugar
Pancreatitis
Gallbladder disease, such as cholecystitis or gallstones
Thyroid cancer
Allergic reactions

All of these are potentially fatal.

After reading these lists, the reasonable reader might wonder, “At what point do the risks outweigh the possible benefits?” For people who cannot control their diabetes, the disease is eventually fatal.

Other messy consequences include blindness and amputation of extremities. So, a roll of the dice with Ozempic might be in order.

Alternatives to a potentially deadly roll of the dice?

However, most people with type II diabetes can control their sugar through dietary and lifestyle modification. These changes are generally not easy, which is why many so people are open to taking a magic shot, courtesy of our consistently trustworthy friends at Big Pharma.

This mindset, which seems to be the basis for Ozempic’s marketing strategy, has really rankled celebrity trainer Jillian Michaels, who has voiced her concerns about Ozempic to Megyn Kelly (video below) and Bill Maher.

As Ms. Michaels explain, Ozempic treatment is necessarily short. And for many patients, the benefits sunset early, as their weight loss plateaus and the pounds rebound. Unfortunately, the side-effects seem to linger³ well beyond patients’ use of the drug.

Another reason for concern is the psychological effect Ozempic seems to have on type II diabetics, who should maintain a strict exercise regimen. According to a report from MSN, Ozempic seems to discourage overweight people from working out⁴.

Is NAD+ optimization a better way to manage insulin resistance?

Dr. Jin-Xiong She is a prominent microbiologist who has spent a significant portion of his career studying the relationship between cellular functions and age-related/metabolic diseases, including type II diabetes.

The precursor to type II diabetes is the condition we call insulin resistance, where the cells do not respond to the insulin’s signal.

This forces the pancreas to produce more insulin, eventually exhausting itself. When the body no longer produces its own insulin, a patient must take insulin orally or via injection. For people in a prediabetic state, insulin resistance causes stubborn weight gain, along with ancillary health problems.

Dr. She has studied the role of NAD in cellular functions, and in this short video, he explains four key benefits of NAD as they pertain to normal insulin sensitivity.

Unfortunately, people lose NAD due to age, stress, and lifestyle choices, such as a poor diet, smoking, alcohol consumption, and a sedentary lifestyle.

This can turn insulin sensitivity into insulin resistance. The good news is that replenishing lost NAD can return the system to healthy homeostasis. Replacing lost NAD is tricky, but Dr. She has developed a highly effective supplement he calls Vitality ↑® NAD+ Booster.

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NAD optimization: a safe, natural path to better health

One of the great benefits of Vitality ↑® NAD+ Booster is the increased energy one feels after just a few days of using the product. This can empower an overweight person with insulin resistance or type II diabetes to hit the gym and get the natural health benefits of exercise.

Many people have been able to reverse type II diabetes and return to good health through dietary and lifestyle modifications. Supplementing to achieve NAD optimization makes the process easier, so more patients should be able to improve their health for the long term.

Importantly, NAD is a natural compound, not a synthetic, so there’s no list of horrendous side effects. I’ve written in this column⁵ about the numerous health benefits I’ve experienced with Vitality ↑® NAD+ Booster. It’s precisely because of those health benefits that I asked Dr. She to make me an affiliate marketer for his company Jinfiniti Precision Medicine.

If you are struggling with insulin resistance or type II diabetes, I urge you to try this amazing product. Ask your doctor which is more likely to help you: the all-natural compound that’s an essential cofactor for virtually every cellular function, or the synthetic hormone with the catchy jingle, a monthly cost equal to your mortgage, and a list of side effects the length of the King James Bible.

O-O-O-I think I know what they’ll say.

Great news: Get started with NAD for only $28!

Vitality ↑® NAD+ Booster has never been more cost-effective than now, because Dr. She is offering an introductory, one-month supply for only $28 dollars with a monthly subscription. That’s a savings of 76 percent, and you can cancel the subscription any time, if you’re not thrilled with the results. Just follow this link: Start for $28!

Disclaimer: The column may contain affiliate links, which help support the website. When you clink on an affiliate link and make a purchase, the website receives a small commission at no additional charge to you. Thank you for your support.

Kevin Rush is an award-winning playwright and screenwriter. He’s the author of three novels, including The Lance and the Veil, an adventure in the time of Christ (which Kirkus Reviews calls “a big, bold Biblical saga to fire the Christian imagination”) and The Wedding Routine, (hailed by Online Book Club as a 4/4 Star romantic comedy delivering “nothing but comic gold”). Learn more at www.kevinrush.us.

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Referenced Sources:

My NAD+ Story: After Three Months, I Feel 30 Years Younger!

Written by Jinfiniti Science on August 10, 2024. Posted in Energy and Fatigue, Guest Blog, NAD, NAD+.

Breakthrough formula restores health and vitality on the cellular level

You may not be aware of this, but a revolution in health sciences is happening, because of discoveries surrounding a compound called nicotinamide adenine dinucleotide, abbreviated as NAD+.

This molecule, as it turns out, is essential for virtually every function of human cells, and not only do we not get enough of it, but aging, stress, and poor lifestyle choices cause a depletion of NAD+ at the cellular level.

NAD+ depletion leads to a wide range of metabolic and age-related disorders, including chronic inflammation, insulin resistance, type II diabetes, cardiovascular disease, chronic fatigue, cancer, and on and on, seemingly ad infinitum.

The good news is that scientists, most notably Dr. Jin-Xiong She in Augusta, Georgia, have developed effective ways to boost intracellular levels of NAD+, thereby restoring youthful vigor and deterring a slew of adult-onset illnesses.

Now, if you’re thinking this pitch sounds too good to be true, I can hardly blame you. As a fourth grader reading about Ponce de Leon, I had to laugh at the gullible rube who was searching Florida for the Fountain of Youth.

And, as you might have read, I’m appalled by corrupt practices in modern medicine¹. But when it comes to all-natural methods of improving my health, I’ll try just about anything once. So, three-plus months ago, I started taking Dr. She’s NAD+ supplement, Vitality ↑® NAD+ Booster, and am I ever happy I did!

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Where did I go wrong?

A little personal background. When I was six, I suffered a nasty whiplash accident that left me with a misaligned spine and a sacrum that was ever-so-slightly out of the socket. My family’s quack doctor said to rest, and I’d been fine.

But I wasn’t fine, and he did nothing to help. As a result, I grew up with atrocious posture and sleeping problems that hampered my growth and left me chronically exhausted.

I was in fairly constant pain, which fluctuated between dull and excruciating, and I had to deal with ever-increasing metabolic health problems, which included a panoply of allergies, tinnitus, “sinus headaches,” a “nervous stomach,” hypoglycemia, and low-level asthma. I was rarely my best self, underperformed at school, lived under constant stress, and simply didn’t have the energy to pursue my life’s goals.

Now, I don’t want to paint a picture of abject misery. I’ve done a lot in my life and have known a great deal of joy and contentment.

And I feel like I’ve earned those moments. I fought for them, exploring every potential avenue to restore my health: chiropractic, Atkins’ diet, cytotoxic four-day rotation diet, nutrient supplementation, meditation, crystals, acupuncture, traditional Chinese herbs, complete abstention from sugar and alcohol, massage therapy, electrical muscle stimulation, and regular exercise.

I poured my meager earnings into expensive treatments that for a time allowed me to feel better before the exhaustion and the pain crept back in.

For the amount of exercise I put in, I should have had a chiseled physique, but I never made the progress others made, and pushing my boundaries resulted in exhaustion, inflammation, and more pain.

Chronic pain/fatigue has been my cross to bear. It’s a lighter cross than many others have endured, and for that I’m grateful.

But it nevertheless has limited my success personally and professionally.

I could recite a litany of times I ended a relationship or made a career change because I was just too tired to move forward.

When I was trying to break in as an actor, a common observation from the agents who interviewed me was, “You need to have more energy.”

As a singer, I never fully developed my voice, because the energy I lacked stunted the development of my vocal instrument.

As a writer, I’ve had a million stories bouncing around in my head that I just haven’t had the time—make that energy—to put down on paper.

So, at age 63, I perceive a huge chasm between my potential, based on an honest assessment of my talent and intelligence, and my accomplishments. Augh, so much spilt milk.

Saved from managed decline by NAD+!

The good news came about four or five months ago when my friend Greta asked if I wanted to do a little marketing writing for a product she was involved with.

At that time, I was feeling every bit of my age. I’d wake up every morning with a song in my heart, but it went something like this:

“Why does everything hurt, hurt, hurt?

Why does everything hurt, hurt, hurt?

Why does every little thing crackle and ping

When I take off my shirt?

It’s a day above dirt,

But why does everything hurt?”

Here’s a brief list of the symptoms I was struggling with:

Asthma
Allergies
Brain fog
Lethargy
Insomnia
Peripheral neuropathy
Swollen feet
Inflammation everywhere
Sciatica and piriformis syndrome
Shoulder impingement syndrome
Tinnitus
Neck pain
Restless leg syndrome and night cramps
Afternoon slump a la Rip Van Winkle

I dutifully exercised for an hour each day to keep these symptoms from worsening, but I was clearly managing my decline, not recovering.

So, then Greta introduced me to Dr. Jin-Xiong She, a molecular biologist who had founded Jinfiniti Precision Medicine.

Dr. She has been studying cellular functions relative to age-related diseases for decades.

His studies confirm that there is one essential nutrient that operates as a cofactor in virtually every cellular function, including the production of energy, a compound called NAD+.

People lose NAD+ with age, leading to a decline in our cells’ ability to perform, which opens the door to various maladies. Supplementing NAD+ can restore cellular performance to peak levels, so we build healthier tissues, bones, and organs.

Dr. She also confirmed through his studies that NAD+ is a difficult nutrient to supplement. Because it’s such a large molecule, it does not penetrate the gut barrier, and even if given intravenously, NAD+ is too large to pass through the vacuoles in the cell membranes.

Thus, the way to boost NAD+ levels is to supplement the precursor molecules, the building blocks of NAD+, and let them enter the cells where the organelles in the cell will use them to create NAD+.

Dr. She claims to have developed the most efficacious NAD+ supplement on the market, and after three months of taking it, I have no reason to doubt him.

Dr. She is a very data-driven scientist, so the first thing he wanted to do with me was draw some blood and measure my levels of essential biomarkers.

Not surprisingly, my NAD+ level was that of a mid-70s man.

The way I figure it, constant stress depleted my levels, and even the strict diet and exercise regimen I’ve been on for decades was not enough to replenish this vital nutrient.

I was also deficient in creatine, which could explain the muscle soreness I experienced after exercising, and I had poor biomarkers for inflammation and antioxidant levels.

Armed with this information, I started taking Dr. She’s NAD+ supplement, Vitality ↑® NAD+ Booster, along with creatine, anti-inflammatory supplements, and antioxidants.

What three months on Vitality ↑® NAD+ Booster has done

I’m now on my third jar of Vitality ↑® NAD+ Booster, and as I wrote at the beginning, I feel like I’m back in my mid-30s. Now, my mid-30s might translate to a fit individual’s early 50s, but I’ll take it, because here’s what I’m experiencing:

Vastly improved overall energy
Deeper sleep
Allergies are milder
Mental fog gone
Better mood
Tightness in my trapezius and neck during computer work/piano playing greatly diminished
Tenderness in the shoulder greatly diminished
Pain/swelling in my feet and lower legs greatly diminished
Sciatica and piriformis pain barely noticeable
Greater flexibility, greater ability to stretch muscles and hold deep stretches longer
Hardly any muscle soreness after exercise
Easier, quicker workouts
Singing is easier with better airflow, greater range, and more power

This is after only three months. Dr. She says he’s been taking Vitality ↑® NAD+ Booster for two years and is still discovering new benefits.

Is NAD+ a real hope for humanity?

In my research, I’ve found that NAD+ optimization is proven or suspected to be beneficial for an incredible number of conditions related to faulty metabolism, genetic mutations, poor neural signaling, and aging, such as:

Addiction
Age-related macular degeneration
Allergies and asthma
Alzheimer’s and Parkinson’s diseases
Autism
Cancer
Cardiovascular disease
Chronic fatigue syndrome
Depression
Female infertility
Insomnia
Low libido
Obesity
PTSD
Type II diabetes and insulin resistance

Now here’s where I offer my disclaimer. Because of my own experience, the mounting hard scientific evidence, and enthusiastic anecdotal testimony, I am sold on Vitality ↑® NAD+ Booster and am excited to share what I know with anyone who could benefit.

So, I asked Dr. She to make me an affiliate marketer for Jinfiniti Precision Medicine.

I think what Dr. She has accomplished is amazing, and the word has to get out to the public. Just thinking about all the unhealthy, suffering people in this country who could benefit and turn their lives around…it makes my head spin.

Get started on NAD+ today and start feeling younger!

So, I invite you, dear reader, to explore Jinfiniti Precision Medicine and make it your source for NAD+ supplementation. If you decide to make a purchase, enter the offer code kevinrush20 for a 20 percent discount off your first purchase, and 10 percent off every subsequent purchase.

If you are suffering from any sort of systemic illness, you need to give your system the fuel it needs to fight back. And if you’re feeling the decline that comes with age, NAD+ can help you turn back the clock and get a youthful spring back in your step.

I’ll continue to keep you updated on this blog about my progress and any new NAD+ discoveries. Until then, good luck and good health!

Update: Get started with NAD+ for only $28!

If you routinely struggle to get a good night’s sleep, you know how insomnia is undermining your health. Do yourself a tremendous favor and order Vitality ↑® NAD+ Booster today. You’ll be very happy you did.

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Referenced Sources:

https://kevinrush.us/2022/08/27/twilight-of-a-quack-tony-fauci-at-sunset/ ↩︎

How NAD Can Support Children on the Autism Spectrum: Strategies and Success Stories

Written by Jinfiniti Science on April 14, 2024. Posted in NAD+, Autism, NAD.

Autism is a developmental disorder that affects communication and behavior.

According to the Centers for Disease Control and Prevention (CDC), autism affects an estimated 1 in 36 children in the United States¹, making it more common than previously thought.

The disorder can manifest in various ways, from mild social challenges to significant communication difficulties and repetitive behaviors.

What’s striking about autism is its indiscriminate nature. It knows no boundaries of wealth, fame, or social status.

Families from all walks of life, including public figures like Elon Musk, Sylvester Stallone, Holly Robinson Peete, Amanda Seyfried, Dylan Dreyer, and Nicole Shanahan, can find themselves navigating the challenges of raising a child with autism.

In this article, we explore…

Groundbreaking strategies that can help improve the lives of children with autism.

How NAD support might be a game-changer in the treatment and support of autism spectrum disorder.

A transformative case study of Corbin, a 3-year-old whose behavior, engagement, and communication skills have dramatically improved after NAD treatment.

Autism Intervention

One of the key issues in the autism community is the need for early detection and intervention.

Research shows that early diagnosis and intervention can significantly improve outcomes for individuals with autism.

However, many families face barriers to timely diagnosis and intervention services, highlighting the importance of raising awareness and ensuring that all children have access to quality care.

Another challenge faced by families affected by autism is the stigma and misconceptions surrounding the disorder.

Many people still hold outdated beliefs about autism, leading to discrimination and social isolation for individuals with autism and their families.

As the exact causes of autism remain not fully understood, research indicates that a combination of genetic and environmental factors contribute to its development.

One emerging area of research focuses on the role of NAD (nicotinamide adenine dinucleotide) deficiency in autism phenotypes².

Autism and NAD

NAD is a coenzyme found in all living cells and plays a crucial role in various cellular processes³, including energy production, DNA repair, and gene expression.

Our research here in Jinfiniti has shown that individuals with autism may have lower levels of NAD compared to neurotypical individuals.

This deficiency could potentially impact mitochondrial function, oxidative stress levels, and neurotransmitter signaling, all of which are involved in the development of autism.

Furthermore, NAD deficiency may also affect other cellular processes, such as immune function and inflammation, which have been linked to autism.

Jinfiniti’s Advocacy on Autism

At Jinfiniti, our mission is to provide innovative treatment for children with autism using NAD.

In fact, we have exciting updates from our ongoing study, showing promising results.

For example, Corbin, a 3-year-old diagnosed with Autism Spectrum Disorder (ASD) following routine childhood vaccinations, has shown remarkable improvement after participating in testing protocols and using the Vitality formulation.

Here are some of the notable improvements observed in Corbin:

Increased focus and engagement: Corbin has been able to sit attentively during therapy sessions and activities and with his teacher during meal times.
Improved fine motor skills: He has demonstrated the ability to put individual popsicle sticks inside a toothbrush holder, indicating progress in his fine motor abilities.
Enhanced communication skills: Despite being non-speaking, Corbin has shown progress in communication by interrupting his teacher to get her attention and indicating his wants and needs more clearly.
Increased independence: Corbin has started opening his lunch snack containers and lunch boxes, showing improved independence in daily tasks.
Improved responsiveness: He now responds with “yeah” when asked if he wants something, indicating better understanding and communication.
Better understanding of verbal commands: Corbin can now follow verbal commands like putting his shoes on, demonstrating improved listening skills.
Increased affection and social engagement: He has been more affectionate and cuddly, initiating play more often with his parents and seeking approval through eye contact.
Expanded vocabulary: Corbin has started saying new words and phrases like “Peek-a-boo,” “I wake up,” and “I pee-pee,” showing progress in his language development.
Improved behavior in public settings: He displayed patience and waiting behavior at the splash pad, a notable improvement from previous behaviors of attempting to run away.

Corbin’s improvements show that the Vitality formulation could be really helpful for kids with autism.

SHOP NAD+ BOOSTER

4 Ways Vitality ↑® NAD+ Booster Can Support Children With Autism

Vitality ↑® NAD+ Booster is a clinically tested blend of NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide that work together to boost NAD levels, rejuvenating cells and the body.

This formulation is particularly beneficial for children with autism, helping improve their behavior and cognitive function in four key ways.

Supports Mitochondrial Function

Mitochondria are often called the “powerhouses” of cells because they produce most of the cell’s adenosine triphosphate (ATP), a molecule that stores and transports energy within cells.

NAD (nicotinamide adenine dinucleotide) is a coenzyme that plays a critical role in mitochondrial function⁴ by shuttling electrons in the electron transport chain, a process that generates ATP.

Research suggests a potential link between mitochondrial dysfunction and autism spectrum disorder (ASD).

Mitochondrial dysfunction can lead to reduced ATP production, affecting cellular processes crucial for brain development and function⁵. This dysfunction may contribute to the development or severity of ASD symptoms.

Boosting NAD levels could theoretically improve mitochondrial function by providing more of the coenzyme needed for efficient ATP production.

This could enhance cellular energy production and potentially support better brain function in individuals with ASD.

Manages Oxidative Stress

Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body.

Free radicals are highly reactive molecules that can cause damage to cells and tissues if their levels are not controlled by antioxidants.

Research has shown that individuals with ASD may experience higher levels of oxidative stress⁶ compared to typically developing individuals.

A study published in the journal Clinical Biochemistry and Nutrition found that children with ASD had significantly higher levels of oxidative stress markers and lower levels of antioxidants compared to typically developing children⁷.

Another study published in the journal Redox Report suggested that oxidative stress may play a role in the development and progression of ASD.

By boosting NAD levels, it is believed that the body’s ability to manage oxidative stress may be enhanced.

This could potentially lead to improved overall health and cognitive function in individuals with ASD.

Supporting NAD levels through supplementation or other means may help mitigate the effects of oxidative stress and improve outcomes for individuals with autism.

Supports Neurotransmitter Signaling

Neurotransmitters are essential for communication between neurons in the brain.

Imbalances in neurotransmitter signaling have been associated with neurological disorders, including autism.⁸

For example, a study published in the journal Frontiers in Psychiatry found alterations in the levels of certain neurotransmitters, such as serotonin and dopamine, in individuals with autism spectrum disorder (ASD)⁹.

By boosting NAD levels, the brain’s ability to maintain proper neurotransmitter balance may be enhanced.

This could lead to improved communication between neurons and potentially enhance cognitive function and overall brain health in individuals with autism.

A study published in the journal Molecular Psychiatry suggested that NADH (a form of NAD) supplementation could modulate dopamine levels in the brain¹⁰, which is important for regulating mood and behavior.

Another study published in the Journal of Neuroscience Research found that NADH supplementation improved cognitive function in a mouse model of Alzheimer’s disease¹¹, which is characterized by neurotransmitter imbalances.

The potential of NAD to restore balance in neurotransmitter signaling is crucial for individuals with autism, as disruptions in this balance can lead to cognitive and behavioral issues.

By supporting NAD levels, it may be possible to help restore this balance and improve communication between neurons, which could have positive effects on cognitive function in individuals with autism.

Supports Healthy Immune Function and Inflammation

Dysregulation of the immune system and chronic inflammation have been linked to various health conditions, including autism.¹²

For example, a study published in the Journal of Neuroinflammation found that children with autism had altered levels of certain immune markers compared to typically developing children¹³.

Another study published in the Journal of Neuroimmunology reported elevated levels of inflammatory markers in the brains of individuals with autism¹⁴.

By boosting NAD levels, it’s possible to modulate immune function and reduce inflammation. This could have several benefits for individuals with autism, including improved overall health and well-being.

One study published in the journal Nature Communications found that NAD supplementation reduced inflammation and oxidative stress in a mouse model of multiple sclerosis¹⁵, a condition characterized by immune dysregulation and inflammation.

That’s why we recommend Vitality ↑® NAD+ Booster for children with autism to support their overall health and well-being.

Vitality ↑® NAD+ Booster is specially formulated with ingredients that work synergistically to promote energy levels, cognitive function, and overall vitality, which can be beneficial for children with autism who may have specific nutritional needs.

It can help support healthy growth and development, as well as provide essential nutrients that may be lacking in their diet.

By incorporating Vitality ↑® NAD+ Booster into their daily routine, children with autism can potentially experience improved energy levels, cognitive function, and overall health, helping them to thrive and reach their full potential.

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Referenced Sources:

RFK Jr.’s VP Pick: Nicole Shanahan, A Voice for Autism

Written by Jinfiniti Science on March 28, 2024. Posted in NAD+, Autism, NAD.

In a move that solidifies his commitment to addressing pressing health issues, Robert F. Kennedy Jr. has chosen Nicole Shanahan as his vice-presidential pick.

What sets Shanahan apart is not just her professional prowess but also her journey as a mother of a child with autism.

This choice highlights the growing prevalence of autism spectrum disorder (ASD) and the need for greater awareness and support for affected families.

Autism is a developmental disorder that affects communication and behavior.

According to the Centers for Disease Control and Prevention (CDC), autism affects an estimated 1 in 36 children in the United States, making it more common than previously thought.

The disorder can manifest in various ways, from mild social challenges to significant communication difficulties and repetitive behaviors.

What’s striking about autism is its indiscriminate nature.

It knows no boundaries of wealth, fame, or social status.

Families from all walks of life can find themselves navigating the challenges of raising a child with autism.

This reality is exemplified by Shananhan’s experience, showing that even those in the public eye are not immune to the disorder’s impact.

Shananhan’s journey as a mother has led her to become a vocal advocate for autism awareness and support.

She has used her platform to raise awareness about the challenges faced by families affected by autism and to advocate for policies that improve access to resources and services for individuals with autism.

In her interview with People Magazine, Shanahan revealed that she had been in discussions with Elon Musk about leveraging technology developed by his Neuralink company.

Neuralink is known for creating an implantable brain-computer interface.

Shanahan expressed interest in exploring how this technology could potentially benefit her daughter, who has autism.

She also shared that a significant portion of her time, over 60%, is dedicated to researching autism and engaging with scientists in discussions about the topic.

“…in part because I am hopeful of helping my daughter overcome her autism, whatever that might look like, whether it be in five years not having a diagnosis anymore, or having all of the tools to navigate the challenges that her diagnosis has produced in her life.”

“This has led me into fields of science that have been utterly fascinating.

“I talk to two scientists a week, typically, whether they’re neurosurgeons or neurologists or mitochondrial experts. Then I spend an equal amount of time after meeting with them trying to digest my notes.

I chat with a lot of other mothers of autistic children because I think mothers are some of the most well-educated and researched.

They’re having to show up for their child every hour of every single day. They’re trying some of these autism interventions and they’re able to tell you with greater accuracy than any published medical paper what they’re seeing in their children.”

Autism Intervention

One of the key issues in the autism community is the need for early detection and intervention.

Research shows that early diagnosis and intervention can significantly improve outcomes for individuals with autism.

However, many families face barriers to accessing timely diagnosis and intervention services, highlighting the importance of raising awareness and ensuring that all children have access to quality care.

Another challenge faced by families affected by autism is the stigma and misconceptions surrounding the disorder.

Many people still hold outdated beliefs about autism, leading to discrimination and social isolation for individuals with autism and their families.

Shananhan’s advocacy work aims to challenge these misconceptions and promote a more inclusive and understanding society.

In addition to raising awareness, Shanahan has also been a strong proponent of increased research funding for autism.

She has supported the University of California Davis Mind Institute through donations, aiding their research and care efforts for individuals with autism and other neurodevelopmental conditions.

As the exact causes of autism remain not fully understood, research indicates that a combination of genetic and environmental factors contribute to its development.

One emerging area of research focuses on the role of NAD (nicotinamide adenine dinucleotide) deficiency in autism phenotypes.

Autism and NAD

NAD is a coenzyme found in all living cells and plays a crucial role in various cellular processes, including energy production, DNA repair, and gene expression.

Our research here in Jinfiniti has shown that individuals with autism may have lower levels of NAD compared to neurotypical individuals.

This deficiency could potentially impact mitochondrial function, oxidative stress levels, and neurotransmitter signaling, all of which are involved in the development of autism.

Furthermore, NAD deficiency may also affect other cellular processes, such as immune function and inflammation, which have been linked to autism.

Jinfiniti’s Advocacy on Autism

At Jinfiniti, our mission is to provide innovative treatment for children with autism using NAD.

In fact, we have exciting updates from our ongoing study, showing promising results.

Here are some of the notable improvements observed in Corbin:

Increased focus and engagement: Corbin has been able to sit attentively during therapy sessions and activities, as well as with his teacher during meal times.
Improved fine motor skills: He has demonstrated the ability to put individual popsicle sticks inside a toothbrush holder, indicating progress in his fine motor abilities.
Enhanced communication skills: Despite being non-speaking, Corbin has shown progress in communication by interrupting his teacher to get her attention and indicating his wants and needs more clearly.
Increased independence: Corbin has started opening his lunch snack containers and lunch boxes, showing improved independence in daily tasks.
Improved responsiveness: He now responds with “yeah” when asked if he wants something, indicating better understanding and communication.
Better understanding of verbal commands: Corbin can now follow verbal commands like putting his shoes on, demonstrating improved listening skills.
Increased affection and social engagement: He has been more affectionate and cuddly, initiating play more often with his parents and seeking approval through eye contact.
Expanded vocabulary: Corbin has started saying new words and phrases like “Peek-a-boo,” “I wake up,” and “I pee-pee,” showing progress in his language development.
Improved behavior in public settings: He displayed patience and waiting behavior at the splash pad, a notable improvement from previous behaviors of attempting to run away.

Corbin’s improvements show that the Vitality formulation could be really helpful for kids with autism.

SHOP NAD+ BOOSTER

4 Ways Vitality ↑® NAD+ Booster Can Support Children With Autism

Vitality ↑® NAD+ Booster is a clinically tested blend of NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide that work together to boost NAD levels, rejuvenating cells and the body.

This formulation is particularly beneficial for children with autism, helping improve their behavior and cognitive function in four key ways.

Supports Mitochondrial Function

Mitochondria are often called the “powerhouses” of cells because they produce most of the cell’s adenosine triphosphate (ATP), a molecule that stores and transports energy within cells.

NAD (nicotinamide adenine dinucleotide) is a coenzyme that plays a critical role in mitochondrial function by shuttling electrons in the electron transport chain, a process that generates ATP.

Research suggests a potential link between mitochondrial dysfunction and autism spectrum disorder (ASD).

Mitochondrial dysfunction can lead to reduced ATP production, affecting cellular processes crucial for brain development and function. This dysfunction may contribute to the development or severity of ASD symptoms.

Boosting NAD levels could theoretically improve mitochondrial function by providing more of the coenzyme needed for efficient ATP production.

This could enhance cellular energy production and potentially support better brain function in individuals with ASD.

Manages Oxidative Stress

Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body.

Free radicals are highly reactive molecules that can cause damage to cells and tissues if their levels are not controlled by antioxidants.

Research has shown that individuals with ASD may experience higher levels of oxidative stress compared to typically developing individuals.

Another study published in the journal Redox Report suggested that oxidative stress may play a role in the development and progression of ASD.

By boosting NAD levels, it is believed that the body’s ability to manage oxidative stress may be enhanced.

This could potentially lead to improved overall health and cognitive function in individuals with ASD.

Supporting NAD levels through supplementation or other means may help mitigate the effects of oxidative stress and improve outcomes for individuals with autism.

Supports Neurotransmitter Signaling

Neurotransmitters are essential for communication between neurons in the brain.

Imbalances in neurotransmitter signaling have been associated with neurological disorders, including autism.

By boosting NAD levels, the brain’s ability to maintain proper neurotransmitter balance may be enhanced.

This could lead to improved communication between neurons and potentially enhance cognitive function and overall brain health in individuals with autism.

A study published in the journal Molecular Psychiatry suggested that NADH (a form of NAD) supplementation could modulate dopamine levels in the brain, which is important for regulating mood and behavior.

Another study published in the Journal of Neuroscience Research found that NADH supplementation improved cognitive function in a mouse model of Alzheimer’s disease, which is characterized by neurotransmitter imbalances.

The potential of NAD to restore balance in neurotransmitter signaling is crucial for individuals with autism, as disruptions in this balance can lead to cognitive and behavioral issues.

Supports Healthy Immune Function and Inflammation

Dysregulation of the immune system and chronic inflammation have been linked to various health conditions, including autism.

For example, a study published in the Journal of Neuroinflammation found that children with autism had altered levels of certain immune markers compared to typically developing children.

Another study published in the Journal of Neuroimmunology reported elevated levels of inflammatory markers in the brains of individuals with autism.

One study published in the journal Nature Communications found that NAD supplementation reduced inflammation and oxidative stress in a mouse model of multiple sclerosis, a condition characterized by immune dysregulation and inflammation.

That’s why we recommend Vitality ↑® NAD+ Booster for children with autism to support their overall health and well-being.

It can help support healthy growth and development, as well as provide essential nutrients that may be lacking in their diet.

SHOP NAD+ BOOSTER

Common Symptoms of Menopause

NAD+ and Ovarian Aging

How NAD+ Can Relieve Menopause Symptoms

NAD+ and Libido During Menopause

Restoring NAD+ Levels Before and After Menopause

Test Your NAD Levels Today

Referenced Sources:

The Link Between NAD+ and Neurodegeneration

Clinical Evidence for NAD+ in Alzheimer’s Disease

Nicotinamide (NAM) vs Placebo

Nicotinamide Mononucleotide (NMN) vs Placebo

Nicotinamide Riboside (NR) vs Placebo

NAD Treatment Approaches

NAD IV Therapy

NAD+ Precursor Compounds

Testing NAD+ Levels to Prevent Cognitive Decline

Referenced Sources:

The Early Struggles: Living the Problem I Wanted to Solve

The Breakthrough: Science Meets Personal Experience

From Personal Mission to National Movement

The RFK Jr. Connection: A Shared Vision for Health Reform

What You Should Know

NAD+ and Aging

The Timeline of NAD+ Decline

What are Normal NAD Levels by Age Group?

Measuring Your NAD Levels

The Gender Gap in Age-Specific NAD+ Levels

Strategies for Increasing NAD+ Levels as You Age

Referenced Sources

Understanding NAD+ and Why It Declines

Common Symptoms of NAD+ Deficiency

Fatigue and Low Energy

Cognitive Symptoms

Skin and Appearance Changes

Poor Sleep Quality

Mental Health and Mood Swings

Metabolic Health Issues

Severe NAD+ Deficiency Symptoms

Cardiovascular Impact of NAD+ Deficiency

NAD+ Deficiency in Specific Populations

How to Test if Your NAD Levels Are Low

How to Treat Low NAD Levels

Referenced Sources:

I was surprised when my dear friend’s cognition declined dramatically overnight at age 94.

When my dear friend reached and passed his 90th birthday with a mind sharp as a tack I assumed he was all clear.

Marshall’s great mind and good memory were perfectly intact until one fateful day.

From one day to the next my friend had forgotten how to use both his cellphone and his computer.

A battery of cognitive tests with a gerontology professional confirmed that he was experiencing mild to moderate dementia.

What if Vitality NAD+ Booster, a NAD supplement formula and known neurotransmitter, could help?

At least 50-65% cognitively recovered.

He knows how to use his phone, he’s back at the computer, those bathroom issues are pretty much gone, and he’s using his walker and cane as well as he formerly had.

He is now back in charge of his meds and supplements because he began to remind me to give him doses as he remembered what to take and when.

Referenced Sources:

NAD+ overcomes insulin resistance without disastrous side effects.

Step 1: Design a catchy ad campaign

What is Ozempic and why should I be skeptical?

Is the bonus benefit just a dangerous illusion?

A litany of side-effects, some of which are deadly

Alternatives to a potentially deadly roll of the dice?

Is NAD+ optimization a better way to manage insulin resistance?

NAD optimization: a safe, natural path to better health

Great news: Get started with NAD for only $28!

Referenced Sources:

Breakthrough formula restores health and vitality on the cellular level

Where did I go wrong?

Saved from managed decline by NAD+!

What three months on Vitality ↑® NAD+ Booster has done

Is NAD+ a real hope for humanity?

Get started on NAD+ today and start feeling younger!

Update: Get started with NAD+ for only $28!

Referenced Sources:

Autism Intervention

Autism and NAD

Jinfiniti’s Advocacy on Autism

4 Ways Vitality ↑® NAD+ Booster Can Support Children With Autism

Supports Mitochondrial Function

Manages Oxidative Stress

Supports Neurotransmitter Signaling

Supports Healthy Immune Function and Inflammation

Referenced Sources:

When my dear friend reached and passed his 90^th birthday with a mind sharp as a tack I assumed he was all clear.