Science behind our
precision formulations

What it is : A direct precursor molecule that converts to NAD+ inside your cells.

Why we chose it : Clinical trials show that 300-900 mg daily NMN supplementation significantly increases blood NAD+ concentrations within 30 days compared to placebo. Research in healthy middle-aged adults shows the sweet spot is 600-900 mg doses. We pair NMN with creatine, D-ribose, and niacinamide because hitting NAD+ production from multiple angles works better than relying on a single pathway. Think of it like accessing a building through the front door, back door, and windows simultaneously instead of just knocking on the front entrance.

Found in : Vitality NAD+ Booster (Powder & Lozenge), Pure NMN Powder

What it is : An alternative NAD+ precursor that works through the Preiss-Handler pathway.

Why we chose it : Multiple studies confirm NR’s ability to increase NAD+ levels and support cellular energy production in aging populations. Research documents a 50% NAD+ increase with NR supplementation.

Some people respond better to NR than NMN, which is why we offer it as an option in our NR2 formula. About 15% of people seem to hit optimal levels faster with NR.

Found in : NR2 NAD+ Booster

What it is : A form of vitamin B3 that feeds directly into the NAD+ salvage pathway, which is how your cells recycle NAD+ from used molecules.

Why we chose it : Research shows niacinamide works in combination with D-ribose to enhance the NAD+ metabolome by up to 27%. Niacinamide absorbs quickly and enters cells easily, making it perfect for multi-pathway formulas.

Your body already uses this pathway naturally. We’re just giving it more raw material.

Found in : Vitality NAD+ Booster, NR2 NAD+ Booster

What it is : A five-carbon sugar that forms the structural backbone of ATP, ADP, and NAD+ molecules.

Why we chose it : Studies show that 1520 mg D-ribose combined with nicotinamide twice daily for just 7 days significantly increases NADP+ by 27% while reducing fatigue and improving mental concentration in healthy middle-aged adults.

Think of D-ribose as the lumber your cells need to build energy molecules from scratch. Without enough raw materials, production slows down

Found in : Vitality NAD+ Booster, NR2 NAD+ Booster

What it is : Adenosine triphosphate in its sodium salt form, identical to the energy molecule your cells produce and use.

Why we chose it : Supplemental ATP bypasses impaired cellular energy pathways. Research shows its potential to restore intracellular ATP levels and support cellular integrity when mitochondrial function is compromised.

The clinically effective dose is 400mg, which improves blood flow and muscle performance during exercise. Your body uses ATP faster than it can produce it during high-intensity activities.

Found in : Creatine + ATP

What it is : An organic compound that rapidly regenerates ATP during high-intensity cellular activities.

Why we chose it : If you took biology in high school or college, you might remember learning about ATP, or adenosine triphosphate. It functions as a battery charger for cells. Creatine facilitates ATP regeneration, helping to keep high-energy-demand organs like muscles and the brain happy.

Research confirms creatine monohydrate supports muscle strength, power output, and recovery across diverse populations from athletes to older adults. Creatine also crosses the blood-brain barrier, supporting cognitive function.

It’s one of the most thoroughly studied supplements in existence, with 30+ years of safety data. Between 3 and 5 grams a day of creatine monohydrate is the range that tends to pop up in study after study.

Found in : Vitality NAD+ Booster, NR2 NAD+ Booster, Creatine + ATP

What it is : A choline compound that crosses the blood-brain barrier and supports acetylcholine production, one of your brain’s most important neurotransmitters.

Why we chose it : A single 630 mg dose of alpha-GPC significantly improves cognitive performance on the Stroop test compared to placebo in healthy males. This demonstrates rapid enhancement of acetylcholine-dependent mental processing.

Your brain uses acetylcholine for memory formation, focus, and learning. Alpha-GPC provides the raw material.

Found in : RejuvenAid

What it is : A compound structurally similar to choline that may support acetylcholine synthesis.

Why we chose it : DMAE functions as a cholinergic compound that supports acetylcholine synthesis. Preliminary evidence suggests cognitive and mood-enhancing properties.

While research on DMAE is more limited than other nootropics, its acetylcholine support complements alpha-GPC in our brain health formula. They work through slightly different mechanisms.

Found in : RejuvenAid

What it is : An amino acid that supports cardiovascular function, calcium regulation, and cellular protection.

Why we chose it : Meta-analysis of randomized controlled trials reveals that taurine supplementation significantly reduces systolic blood pressure across multiple populations. It supports cardiovascular function through calcium regulation and antioxidant effects.

Taurine levels naturally decline with age, making supplementation increasingly relevant after 40. Your heart and brain contain high concentrations of taurine for a reason.

Found in : RejuvenAid

What it is :A unique amino acid antioxidant that accumulates in mitochondria (your cell’s energy factories).

Why we chose it : L-ergothioneine acts as a unique mitochondrial antioxidant with selective uptake mechanisms. Your cells have a specific transporter protein just for ergothioneine, suggesting it plays an important role that scientists are still uncovering.

Research shows promise in protecting cells from oxidative stress and supporting longevity pathways. When your cells go out of their way to collect something specific, it’s worth paying attention.

Found in : RejuvenAid

What it is :A dipeptide (two amino acids bonded together) found naturally in muscle and brain tissue.

Why we chose it : L-carnosine’s anti-glycation properties help prevent the formation of advanced glycation end-products (AGEs). These sticky protein complexes accelerate aging and contribute to many age-related conditions.

Carnosine levels drop by more than 60% between ages 10 and 70, making supplementation a logical intervention. Your body stops producing enough on its own.

Found in : RejuvenAid

What it is :A flavonoid (plant compound) found in strawberries and other fruits that clears senescent cells from your body.

Why we chose it : Clinical trials demonstrate that fisetin supplementation significantly reduces senescence markers including MMP-3, TGFβ-1, and MMP-12 while decreasing senescent cell burden in peripheral blood.

Research identifies fisetin as one of the most potent natural senolytic compounds available. Senescent cells are “zombie cells” that refuse to die and secrete inflammatory signals that damage neighboring healthy cells.

Found in : SenoAid

What it is :A flavonoid antioxidant that works side-by-side with fisetin to clear senescent cells.

Why we chose it : Studies show 1000 mg daily quercetin for 14 days significantly accelerates recovery of neuromuscular function and reduces muscle soreness within 24 hours after exercise-induced damage. It demonstrates powerful anti-inflammatory and recovery-promoting effects.

When combined with fisetin, quercetin creates a more complete senolytic effect than either compound alone. They tag-team the problem from different angles.

Found in : SenoAid, Extra Strength Turmeric+

What it is :The active compound in turmeric that gives the spice its golden color and anti-inflammatory effects.

Why we chose it : Clinical trials consistently demonstrate curcumin’s anti-inflammatory effects through inhibition of key inflammatory pathways including NF-κB and COX-2.

The challenge with curcumin is absorption. Your digestive system doesn’t absorb it well, which is why we combine it with piperine. This combination increases bioavailability by 2000%, making the curcumin you take actually reach your cells instead of passing through unused.

Found in : Extra Strength Turmeric+

What it is :An extract from the Boswellia serrata tree that contains boswellic acids with anti-inflammatory properties.

Why we chose it : Boswellia serrata extract (300 mg) demonstrates rapid anti-inflammatory action, significantly reducing pain scores within just 5 days in knee osteoarthritis patients. It also decreases inflammatory biomarkers TNF-α, hs-CRP, and IL-6.

Boswellia works through different mechanisms than curcumin, creating a complementary anti-inflammatory effect. One blocks inflammatory signals, the other prevents them from forming in the first place.

Found in : Extra Strength Turmeric+

What it is :A rhizome (underground stem) used for centuries in traditional medicine, now validated by modern research.

Why we chose it : A comprehensive systematic review of 109 randomized controlled trials confirms that 1500 mg daily ginger supplementation effectively alleviates nausea, reduces inflammation, improves digestive function, and supports metabolic health with excellent safety profiles.

Ginger’s gingerols and shogaols work through pathways distinct from curcumin and boswellia. Three different anti-inflammatory mechanisms in one formula.

Found in : Extra Strength Turmeric+

What it is :A concentrated source of catechins, particularly EGCG (epigallocatechin gallate), from green tea leaves.

Why we chose it : Sixty-day green tea extract supplementation significantly increases fat oxidation by 11%, improves insulin sensitivity, and reduces waist circumference by over 1 cm in overweight postmenopausal women.

Beyond weight management, EGCG supports cellular health through multiple antioxidant mechanisms. We include it in SenoAid for its cellular protection properties that complement the senolytic compounds.

Found in : SenoAid

What it is :A protein-digesting enzyme extracted from pineapple stems.

Why we chose it : Clinical trials show that oral bromelain combined with trypsin and rutoside significantly reduces C-reactive protein levels and patient-reported pain while accelerating post-operative recovery.

Bromelain also enhances the absorption of quercetin and other flavonoids, making it a strategic addition to our senolytic formula. It pulls double duty as both an active ingredient and an absorption enhancer.

Found in : SenoAid

What it is :An alkaloid compound extracted from several plants, including barberry and goldenseal.

Why we chose it : Randomized controlled trials demonstrate that 1500 mg daily berberine for 3 months reduces fasting blood glucose from 10.6 to 6.9 mmol/L and decreases insulin resistance by 44.7% in type 2 diabetes patients. Its efficacy rivals metformin.

Berberine activates AMPK, your cell’s metabolic master switch, improving how your body handles glucose and fat. Studies show it reduces LDL cholesterol by 25% and supports healthy body weight.

Found in : Natural Berberine+

What it is :A traditional Chinese medicine herb used for immune support and longevity.

Why we chose it : Emerging research suggests telomerase activation properties and immunomodulatory effects that may contribute to healthy aging. Telomeres are the protective caps on your chromosomes that shorten as you age.

We include it in Natural Berberine+ to complement berberine’s metabolic effects with immune system support. Your metabolism and immune function are more connected than most people realize.

Found in : Natural Berberine+

What it is :The form of vitamin D your skin produces from sunlight exposure.

Why we chose it : Vitamin D3 supplementation supports bone mineralization, immune function, and calcium homeostasis. About 70% of adults have insufficient vitamin D levels, making supplementation necessary for most people.

Your body needs vitamin D to absorb calcium. Without adequate D3, you could take all the calcium in the world and your bones still wouldn’t get it.

Found in : Vitamin D3 + K2

What it is :Menaquinone-7, the longest-acting form of vitamin K2 that stays active in your body for 72 hours.

Why we chose it : Three-year clinical trials show that vitamin K2 as MK-7 supplementation significantly increases lumbar spine bone mineral density and reduces undercarboxylated osteocalcin. It activates bone-building proteins while preventing age-related bone deterioration.

Here’s why K2 matters: without it, calcium can end up in your arteries instead of your bones. D3 helps you absorb calcium, K2 makes sure it goes to the right place.

Found in : Vitamin D3 + K2

What it is :An essential mineral in two highly bioavailable forms.

Why we chose it : Magnesium supplementation supports over 300 enzymatic reactions, improves muscle function, enhances energy production, and promotes cardiovascular health.

We use magnesium malate for its role in energy production (malate is part of the Krebs cycle, which generates ATP) and glycinate for its superior absorption and calming properties. Most people don’t get enough magnesium from food alone.

Found in : Vital Minerals Complex

What it is :Calcium bound to citric acid, which absorbs well even without stomach acid.

Why we chose it : Calcium citrate provides highly absorbable elemental calcium that works in combination with vitamin D3 and vitamin K2. This trio ensures calcium ends up strengthening your bones rather than calcifying your arteries.

We maintain a 2:1 calcium-to-magnesium ratio for optimal mineral balance. These minerals compete for absorption, so the ratio matters.

Found in : Vital Minerals Complex

What it is :Selenium bound to the amino acid glycine for superior absorption.

Why we chose it : Selenium in its organic glycinate form provides bioavailability for supporting antioxidant defense systems through selenoprotein synthesis. It plays a role in thyroid hormone metabolism and immune function.

The thyroid gland has the highest selenium concentration of any organ, making adequate selenium intake necessary for thyroid health. Your thyroid literally hoards selenium because it needs it that badly.

Found in : Vital Minerals Complex