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The impact of dementia goes far beyond the person who is diagnosed; it also deeply affects their families, who struggle with the emotional and mental pain of seeing their loved ones’ memories fade away.
Watching someone you care about lose the ability to do everyday things, forget important moments, or fail to recognize familiar faces can be incredibly hard.
Families often feel helpless and overwhelmed, desperately searching for ways to restore what has been lost.
But there is hope.
Take Marshall, a 94-year-old who completely forgot how to use his phone and computer after being diagnosed with dementia.
His story shows that it’s possible to regain lost memories and improve mental clarity.
We hope that you or your loved ones can also benefit from optimizing your NAD+ levels.
Read Marshall’s story below.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.
I’m not sure what I expected, but…
I was surprised when my dear friend’s cognition declined dramatically overnight at age 94.
Sure, there had been some memory lapses over the course of his 93rd year.
He occasionally forgot his house keys when he went out. He didn’t always remember everything he had driven to the grocery store to buy. (Yes, he was still driving safely at age 92 and beyond.)
Those lapses were the kind that everyone I know over the age of 40 has complained about, myself included.
Still, the signs of Marshall’s cognitive decline did not progress over the course of weeks or months, as I had believed they would, were they to happen at all.
I had hoped that he was past some imaginary statistical cutoff date by which I had presumed dementia would happen. I had read somewhere that by the age of 80, 1 in 6 people experienced some degree of dementia.
When my dear friend reached and passed his 90th birthday with a mind sharp as a tack I assumed he was all clear.
By the time he celebrated his 94th birthday, I relished the fact that he remembered things better than many 40-year-olds and he still “figured stuff out” (his phrase) really well for a person of any age.
Give him a problem to solve and if he hadn’t done so by day’s end, he would always spring out of bed the next day declaring, “I’ve got it!” having solved the problem throughout the night.
Marshall’s great mind and good memory were perfectly intact until one fateful day.
That day I discovered him sitting on his bed staring quizzically at his phone.
I asked him, “What are you doing, M?” He looked at me, bewildered, and replied, “I don’t know.”
I pressed him further. “What do you mean, ‘You don’t know’? Are you trying to call someone on your phone?” I asked.
“I’m trying to figure that out,” he told me. “I’m working on it.”
His words weren’t making sense to me. Working on what? What did he mean?
“Marshall,” I began, worried, “What do you mean ‘working on it”? What’s to work on? Just make the call if that’s what you’re trying to do.”
He looked at me with a blank expression and replied, “I don’t know how.”
I flashed back to years earlier when a very beloved actor friend of mine had called me at my apartment in New York City. He was talking to me in disconnected, somewhat incoherent phrases that I couldn’t understand.
Clearly, something was wrong.
I asked him where he was and he somehow managed to tell me with words that made some sense that he was at the nearby Apple Store.
I told him to stay where he was, that I would be right over. I quickly threw on a jacket and ran the four blocks to the store.
I found my friend sitting at a display bench downstairs in the store with an Apple clerk who seemed concerned.
My friend was insisting that she sell him a new iPhone, which she explained to me she didn’t want to do because his current model phone was working just fine.
I told her to cancel the order, which she didn’t want to place anyway.
I asked him a few questions, which he answered only somewhat coherently.
I apologized to the salesgirl and walked my friend out of the store. I found a bench where he could sit comfortably while I called his family at their home.
They were understandably concerned when I told them about his condition.
They were in another state but together we made the decision that I should get him to the nearest Urgent Care.
The staff there quickly diagnosed a suspected stroke and, with their help, I hastily got my friend to a nearby hospital.
He spent a week in the hospital and recovered, but things could have gone in a whole other direction had I not jumped into action when I did.
Was Marshall suffering the effects of a stroke? I determined to keep a close eye on him throughout that entire day.
I observed him sitting and staring into space from time to time, as though lost in thought.
When I asked him what he was thinking about, he said, “I’m figuring something out,” and he would return to gazing off into the distance with a vacant stare.
Later that day I discovered him sitting at his computer, staring at the screen, immobile.
“What are you doing, Marshall?” I asked him.
“I don’t know. I can’t answer that,” he said, clearly frustrated and confounded.
From one day to the next my friend had forgotten how to use both his cellphone and his computer.
Worse, he seemed “not all there” mentally.
There’s more but I won’t go into the details, which included some bathroom and basic walking issues. Suffice it to say he had devolved significantly over just 24 hours.
Over the next weeks, I took my friend from doctor to specialist to lab to ascertain exactly what was going on.
A brain MRI (not fun for him at all) ruled out any suspected brain mass/tumor but…
A battery of cognitive tests with a gerontology professional confirmed that he was experiencing mild to moderate dementia.
Watching him take that cognition test was painful because questions that he would have aced just the week before gave him great difficulty in answering.
He couldn’t even begin to draw the clock face requested in the test.
A former whiz with numbers, he was stumped when asked to count back from 100 in 7’s. (100, 93, 86, etc.) His frustration turned to anger and eventually, he refused to participate in completing the test.
Once home, I was shocked to discover that Marshall had completely mixed up his daily meds.
As a forever health freak and gym rat, he had always been compliant and rigorous with taking vitamins and the few prescriptions he was on.
He had gone on his first prescription meds just a few years before when diagnosed with non-small-cell lung cancer.
He was doing ok with that disease, given his age and the severity of such a condition.
The health equity he had built up over decades of clean, healthy living stood him in good stead to do battle with cancer.
He never missed a prescribed dose of anything the oncologist ordered and his vitamin game was strong after years of taking a full regimen of fitness and bodybuilder supplements.
However, a review of his medicine cabinet that day showed that things had gone very awry.
Some bottles that I knew should be there were missing and others contained far too many pills than they should have since the date of fulfillment at the pharmacy.
When I asked him if he had been taking his pills regularly, as he had always done, he looked at me with that new vacant, uncomprehending stare.
I took possession of all bottles from his bathroom shelf and called all of his prescribing doctors to review his treatment plan and get him back on track.
I took over the administration of meds and supplements. I felt lucky to have discovered the issue when I did.
Fortunately, doing some math on the bottles and the number of pills inside them proved that the pill problem had occurred concurrently with the cellphone and computer problem. Suddenly and recently.
With a heavy heart, I booked tours of Assisted Living homes in advance of what I was sure would soon be the need for 24/7 memory care.
It is a favorite of mine and so many others for energy mental clarity and more. Why not give it a try?
That night I gave Marshall his first dose of the clinically-proven powder. The next morning? Nothing short of a medical miracle.
I could kick myself for not having recorded the “before” Vitality NAD+ Booster Marshall to the man who woke up that next day.
When I claim a 50% improvement in his cognition OVERNIGHT it sounds preposterous even to me!
Except I witnessed it. I continue to see it daily.
Has he suddenly regained 100% of his memory and ability to solve problems and think clearly?
Most definitely not. He is, however…
At least 50-65% cognitively recovered.
He knows how to use his phone, he’s back at the computer, those bathroom issues are pretty much gone, and he’s using his walker and cane as well as he formerly had.
He is now back in charge of his meds and supplements because he began to remind me to give him doses as he remembered what to take and when.
I check daily to make sure he has not forgotten anything, of course, but so far, so good.
When he sees me coming with it, his eyes light up and he says, “Dr. She’s stuff?” and I shake my head “yes” in acknowledgment.
I think he looks forward to it because he knows the good it does him.
During a doctor visit with his Primary Care Physician yesterday, the doctor acknowledged the improvement he saw in Marshall.
I told him what I had added to the program and he said, “Well great, there is good data on that supplement.”
He’s one of the physicians I had taken Marshall to see to evaluate the sudden mental decline.
He’s the same doctor who had told me back then several months ago that Marshall could not be left alone anymore.
“If he can’t use his phone and he gets in trouble, it’s a big problem,” he advised.
Plus, he mentioned the stove incident that had happened during that awful week:
Marshall had turned on a gas burner that didn’t light and some gas fumes escaped before I noticed what was happening.
I’m grateful for however many months, hopefully, even years, that this product will enable my dear friend to enjoy his mind and his memory.
If it stopped working tomorrow, I would still be grateful today for the past six weeks of improvement.
Dementia moves in and makes itself at home with all too many families today. It’s a significant global health challenge.
Here are some key statistics highlighting the fact that it’s not “if” it’s “when” a friend, neighbor, work colleague, or family member of yours may experience this heartbreaking condition:
Global Prevalence: As of 2023, more than 55 million people worldwide are living with dementia. This number is expected to nearly triple by 2050, reaching 139 million due to aging populations.
Incidence: Around 10 million new cases of dementia are diagnosed each year. That equates to one new case every 3 seconds.
Age Factor: Dementia primarily affects older adults. About 1 in 6 people over the age of 80 have dementia. However, early-onset dementia, which occurs before the age of 65, accounts for about 9% of cases.
Economic Impact: The global cost of dementia is estimated to be over $1 trillion annually, including healthcare costs, informal care, and loss of productivity. This figure is projected to increase significantly in the coming decades.
Mortality: Dementia is one of the leading causes of death worldwide. In many countries, it ranks as the second or third leading cause of death among older adults.
Gender Disparity: Women are disproportionately affected by dementia. Approximately two-thirds of people with dementia are women, partly because women tend to live longer than men.
Alzheimer’s Disease: Alzheimer’s disease is the most common form of dementia, accounting for 60-70% of all cases.
These statistics underscore the importance of research, prevention, and support for those affected by dementia.
NAD, nicotinamide adenine dinucleotide, is a vital coenzyme that enables mitochondria, the powerhouses of your cells, to produce cellular energy in the form of ATP. Without NAD, survival beyond a few minutes is impossible.
NAD exists in two natural forms: NAD+ and NADH. They work together to transfer electrons and help many enzymes to function.
NAD+ is depleted by some important enzymes and its level rapidly declines with age.
NAD deficiency contributes to fatigue, brain fog, poor sleep, arthritis, metabolic syndromes, weight gain, inflammation, and other health conditions.
Most health benefits of NAD can only be realized when the level is optimized.
High-quality oral supplements can easily optimize NAD levels.
Jinfiniti’s patented NAD+ supplement, Vitality Boost, is the best NAD+ Booster.
As a special offer for you, we invite you to try Vitality Boost with a 20% discount using coupon code Blog20. Don’t miss this unique opportunity to enhance your health and vitality. Click here to order.
In this article, Professor Jin She will discuss the following critical points:
How NAD can turn back the clock on age-related health issues, boosting both your lifespan and healthspan.
7 powerful ways NAD can transform your health from the inside out.
2 key strategies to tackle oxidative stress, DNA damage, blood sugar imbalances, chronic inflammation, metabolic dysfunction, and cellular senescence.
Professor Jin She’s TAO paradigm (Test, Act, Optimize), a proven approach to optimizing your NAD and other biomarkers as well as your health and longevity.
In the pursuit of wellness and longevity, NAD has emerged as the most important area of interest among scientists and consumers.
Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme found in all living cells, playing a crucial role in over 500 cellular processes. The most important one is the production of cellular energy, ATP, that all cells need to function. NAD is also responsible for many chronic diseases like obesity, diabetes, cardiovascular diseases, and neurodegenerative disorders.
NAD supplementation has been widely recommended by doctors and used by millions of consumers. However, it is still not widely known that the full benefits of NAD are only realized when your NAD levels are optimized.
How can you optimize your NAD so that you achieve your full potential and live healthier and longer? There is only one approach that works. That is TAO: test, act and optimize.
Read this blog and download our free eBook guide on NAD, you will appreciate more the science, the benefits and more importantly the how to get all the benefits of optimized NAD levels.
What is NAD Optimization?
NAD optimization involves strategies to increase and maintain optimal levels of NAD in the body.
As we age, our cells experience a decline in NAD levels.
This decline contributes to various aspects of aging, including cellular dysfunction, mitochondrial dysfunction, and DNA damage.
Both research studies and extensive consumer data have shown that replenishing NAD levels can slow down or reverse many age-related health conditions, definitely extending health span, the period of life without major diseases or injuries, and likely extending lifespan via extended improved health.
Role of NAD in Cellular Function
One of the most important roles of NAD is its involvement in cellular energy production.
Additionally, NAD is involved in DNA repair, gene expression, and the regulation of over 500 different cellular processes partly through its interaction with sirtuins, a class of proteins involved in longevity and aging.
Boosting NAD levels can also improve mitochondrial function, increase energy production, and improve many health biomarkers such as liver function, kidney function, and insulin sensitivity, just to name a few.
Data from tens of thousands of our customers clearly indicate that over 80% of people who have optimized NAD by our NAD supplement, the Vitality Boost, have seen health benefits in various areas including but not limited to more energy, better sleep, better mental clarity, higher performance and recovery.
7 Top Benefits of Healthy NAD Levels
Enhanced Energy Production:
Maintaining healthy NAD levels is essential for optimal cellular metabolism, as NAD is a key player in cellular respiration. This process converts nutrients into energy, leading to increased ATP production.
With higher NAD levels, cells can produce energy more efficiently, resulting in enhanced overall energy levels and reduced fatigue. Additionally, NAD supports mitochondrial health, ensuring that these cellular powerhouses function effectively and produce less toxic substances, namely free radicals.
Improved Metabolic Health:
NAD plays a crucial role in regulating metabolism, including glucose and lipid metabolism. Healthy NAD levels help maintain stable blood sugar and cholesterol levels, reducing the risk of metabolic disorders.
By supporting metabolic efficiency, NAD can aid in weight management and combat obesity, and reduce insulin resistance and risk for diabetes, making it a vital component of overall metabolic health.
Healthy NAD levels support these repair processes, extending the lifespan of cells and tissues and contributing to overall cellular longevity.
Cognitive Function:
Healthy NAD levels are crucial for brain health, as NAD is a neurotransmitter and supports the production of ATP in brain cells, ensuring they have the energy needed to function optimally.
NAD also plays a role in neuroprotection, helping to safeguard neurons from damage and potentially reducing the risk of neurodegenerative diseases, thereby enhancing cognitive function and memory.
It also helps in faster recovery by reducing muscle soreness and inflammation after intense exercise, allowing athletes to train harder and longer with quicker recovery times.
Aging Optimization:
NAD levels naturally decline with age, contributing to various age-related declines in function. By maintaining healthy NAD levels, it is possible to support cellular health and slow down the aging process.
This includes improved skin health, where NAD helps maintain skin elasticity and reduce the appearance of wrinkles, promoting a more youthful appearance.
Immune System Support:
NAD is vital for a robust immune system, as it is involved in the production and function of immune cells. Healthy NAD levels enhance the immune response, helping the body to fight off infections and diseases more effectively.
Additionally, NAD helps regulate inflammatory responses, reducing chronic inflammation that can contribute to various health issues, thereby supporting overall immune health. NAD can also reduce symptoms of allergies and asthma in many individuals.
With all these benefits, how can you optimize your NAD levels and live a healthy, fulfilling life?
How Jinfiniti Can Optimize Your NAD Levels
At Jinfiniti, we aim to alleviate debilitating conditions such as oxidative stress, DNA damage, blood sugar imbalances, chronic inflammation, metabolic dysfunction, and cellular senescence through two key approaches:
1. Finding & Tackling the Root Causes
2. Adhering to the 8 Pillars of TAO for Optimal Health
Taoism (道) is an ancient Chinese philosophy that explains the workings of the universe, emphasizing the balance and harmony of Yin and Yang, two opposite but interconnected forces.
To achieve health and longevity, one must maintain cellular harmony through a holistic approach.
The Jinfiniti Approach
We use the Intracellular NAD test to provide precise data, avoiding guesswork and optimizing your NAD levels.
This test, the first and most reliable one on the market, helps determine NAD deficiency, assess supplement effectiveness, and find the optimal dosage for your needs.
It also provides actionable data to adjust the dosage of NAD supplements or other NAD products, optimizing your NAD levels and helping manage chronic diseases.
Based on the test results, we prescribe customized approaches to manage symptoms and chronic diseases at the cellular level.
After 3 to 4 weeks of action, take a second test to assess your new levels. You’ll likely see significant changes, especially if you follow our protocol and use our products.
With the results of the Intracellular NAD test, you’ll know which actions yield progress.
Repeat these actions consistently for optimal health and longevity.
Why should you optimize your NAD levels?
1. How is an optimal level of NAD defined?
Like any biomarker, defining the optimal range is a critical but difficult process. This range may change slightly as additional data becomes available. There are major differences between the normal ranges that medical organizations usually use and the optimal range that functional medicine or health optimization organizations prefer to use.
Normal ranges are values that we see in the vast majority of people who appear to be healthy, while optimal ranges are values within which you can perform the best and maximize your health span and lifespan.
For Intracellular NAD, Jinfiniti conducted extensive studies and proposed to define the lower end of the optimal range as the 75th percentile of NAD levels we see in teenagers, meaning that NAD levels are higher than the value in 75% of teenagers. This value is 40µM (micromolar).
2. Too low NAD level is bad for health
It turned out that young individuals with NAD levels less than 40µM often have certain health or subhealth issues such as autism, autoimmune diseases, and allergies.
We also found that individuals who can increase their NAD levels to above 40µM, especially above 50µM, usually experience significant health benefits including more energy, better sleep, improved mental focus, and reduced symptoms related to allergy, asthma, arthritis, diabetes, blood pressure, and others.
In an extreme case, a baby boy in a coma for six months was cured by our NAD product.
We shall emphasize that the dosage required by each person to optimize his or her NAD is different. If you do not take enough, you may not increase your NAD level at all and do not gain any health benefits.
Therefore, you must take a NAD test at least after supplementation to determine whether your action is producing the result you need and deserve. Otherwise, you may be just wasting your money and time.
3. Too high level of NAD is also bad.
Accumulating evidence suggests that one should not elevate their NAD level above 100µM, a threshold beyond which it may become harmful. Known harm includes an increase in vascular inflammation and cardiovascular disease. We see about 5% of the individuals overdosing on their NAD supplements in our large dataset.
To summarize, the optimal NAD range is 40-100µM. One shall not guess, test!
Two Steps to Optimize your NAD levels
If you want to optimize your NAD levels and combat age-related chronic diseases, here are two things you need to do:
Step 1: Order the Intracellular NAD test today.
Order the Intracellular NAD test today and use it as soon as it arrives. This test can help you determine if you are deficient in NAD, assess the effectiveness of your NAD supplement, and find the optimal dosage for your needs.
Additionally, the test provides actionable data to help you adjust the dosage of Vitality Boost, optimizing your NAD levels and helping you manage chronic fatigue.
When it comes to boosting your NAD levels, there’s nothing quite like Vitality Boost.
This patented supplement is meticulously formulated by two world-class scientists in cellular health to provide a potent blend of natural ingredients that work synergistically to enhance your vitality and combat chronic diseases proactively.
It is a clinically validated formulation consisting of multiple NAD precursors, NAD+ precursor, D-Ribose and Nicotinamide as well as Creatine monohydrate that stores your ATP when you do not need them. These ingredients have their own health benefits and in the golden ratio work synergistically to help:
Manage fatigue
Boost energy and improve performance
Improve sleep quality
Support inflammation, muscle, and joint pains
Support healthy allergic and asthmatic symptoms
Improve mental clarity and dementia symptoms
Support functions of many organs (liver, kidney, heart, thyroid, fertility)…
In other words, Vitality Boost supports healthy NAD levels to revitalize your cells, optimize your mitochondria, and improve your energy so you can do things you love!
Start by using the first Intracellular NAD® test to reveal your current NAD levels. Then, take Vitality Boost for a month.
After 3-4 weeks, use the second Intracellular NAD® test to identify your new, optimized levels after taking our NAD supplements. You’ll be pleasantly surprised by how much your levels have improved.
If you’re unsure about what to do or have questions about how to start or interpret your results, you can book your free consultation.
It turned out that many young people with f our Vitality Boost fails to increase your NAD levels, just send us a message within 60 days and we will gladly refund your supplement purchase.
Please note that tests are non-refundable.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.
Diabetes does not discriminate, but certain populations are more vulnerable.
Adults over the age of 45, individuals with a family history of diabetes, and those with obesity are at higher risk.
These people have impaired insulin regulation, leading to persistent high blood sugar levels, known as hyperglycemia.
This can lead to serious health complications—such as cardiovascular disease, neuropathy (nerve damage), kidney damage, blindness, and diabetic ketoacidosis, to name a few—if not properly managed.
While many are familiar with the common symptoms of diabetes such as frequent urination, increased thirst, and fatigue, several lesser-known signs might indicate the presence of this condition.
Here are 12 uncommon signs of diabetes to be aware of:
1. Darkened Skin Patches (Acanthosis Nigricans)
Have you ever noticed dark, velvety patches on your skin, especially in areas like your neck, armpits, or groin?
This condition is known as acanthosis nigricans, and while it might seem harmless or just a cosmetic issue, it can actually be an important indicator of what’s happening inside your body.
When your skin develops these dark patches, it’s often a sign that your body is becoming resistant to insulin.
Insulin resistance is a condition where your body’s cells don’t respond properly to insulin, the hormone that regulates blood sugar.
When your cells resist insulin, your body needs to produce more of it to keep your blood sugar levels in check.
This overproduction can lead to higher levels of insulin in your blood, which then causes the skin cells to multiply faster than usual, resulting in those dark patches.
So, if you ever spot these dark patches on your skin, don’t just brush them off.
They could be an early warning sign that your body is struggling with insulin resistance, and it’s a good idea to get your blood sugar levels checked.
2. Frequent Yeast Infections
Frequent yeast infections aren’t just annoying—it could actually be a sign that something’s off with your blood sugar levels.
When your blood sugar is high, it creates the perfect environment for yeast to thrive. This is because yeast feeds on sugar, so the more sugar there is in your system, the more it can grow.
For women, this often means recurrent vaginal yeast infections. But it’s not just limited to that—both men and women can get skin infections or oral yeast infections, also known as thrush.
Therefore, if you notice you’re getting these infections more often than usual, it might be your body’s way of telling you to check your blood sugar.
So, if you find yourself dealing with wounds that seem to linger, it might be worth getting your blood sugar checked.
4. Tingling or Numbness in Hands and Feet (Peripheral Neuropathy)
Do you ever feel a strange tingling or numbness in your hands and feet, almost like a burning sensation?
This is something called peripheral neuropathy, and it’s pretty common in people with diabetes.
When your blood sugar stays elevated for too long, it can start to damage the nerves, especially in your extremities.
These nerves are super important for sending signals back and forth between your brain and the rest of your body. When they get damaged, you can start to feel that tingling, numbness, or even burning sensation.
And it’s not just a minor discomfort—it’s your body’s way of telling you that something’s up.
For example, a study published in Diabetes Care found a significant correlation between high blood sugar levels and the development of peripheral neuropathy.
When your blood sugar spikes and drops, it doesn’t just affect your energy levels—it can also impact your eyes.
High blood sugar levels cause the lenses in your eyes to swell, which changes their shape and how they focus light. This can lead to periodic blurriness or sudden shifts in how clearly you see things.
Think of your eye as a camera. If the lens isn’t the right shape, the pictures come out blurry. The same thing happens with your vision when your blood sugar is out of whack.
These changes can cause the lens to swell and then return to normal once blood sugar levels stabilize, which explains why your vision might be clear one day and blurry the next.
6. Hearing Impairment
Diabetes can affect so many parts of your body, and your ears are no exception.
High blood sugar levels can damage the blood vessels and nerves in your ears, which can lead to hearing problems.
Just like diabetes can cause damage to the nerves in your hands and feet, it can also impact the delicate structures in your ears.
This can make it harder to hear clearly and can even lead to sudden hearing loss.
The researchers suggest that high blood sugar levels can damage the small blood vessels and nerves in the inner ear, leading to hearing loss.
Therefore, if you’re noticing changes in your hearing, it’s a good idea to get your blood sugar levels checked. It could be a sign that your diabetes needs better management, and addressing it could help prevent further damage.
7. Gum Disease and Oral Health Problems
Red, swollen, or bleeding gums?
It might not just be a dental hygiene issue—it could actually be linked to your blood sugar levels.
When your blood sugar is high, it can weaken your immune system, which makes your gums more susceptible to infections. This can lead to gum disease and other oral health problems.
High blood sugar provides a perfect environment for bacteria to thrive, which can lead to infections in your mouth.
Your immune system is already working harder to manage your blood sugar, so it has less capacity to fight off these bacteria. This is why people with diabetes are more prone to gum disease.
Therefore, if you or someone you know has diabetes and notices this unusual breath smell, it’s crucial to seek medical attention right away. It’s your body’s way of signaling that it needs help, and catching it early can prevent serious complications.
9. Extreme Hunger
Have you ever felt constantly hungry, no matter how much you eat? Like you just finished a meal, but your stomach is already growling again?
This persistent and excessive hunger can actually be a sign that your blood sugar levels are out of balance.
When you have diabetes, your cells can have trouble getting the glucose they need for energy.
Even though there’s plenty of sugar in your blood, it can’t get into the cells without enough insulin. So, your body responds by making you feel hungry, trying to get more energy.
It’s like your cells are starving in the middle of a feast.
They need glucose to function, but without insulin to help move the glucose into the cells, they can’t access it.
This leads to a vicious cycle of eating more but still feeling hungry because the cells remain deprived of the energy they need.
10. Unexplained Weight Loss
Are you losing weight without even trying?
While it might sound like a dream come true for some, unexplained weight loss can actually be a sign of something serious, especially if you have diabetes.
In type 1 diabetes, your body can’t produce enough insulin to help glucose get into your cells. Without this vital energy source, your body starts breaking down muscle and fat for energy instead, which leads to weight loss.
Imagine your body is like a car that suddenly can’t get gas, so it starts using up its own parts to keep running.
This process is your body’s desperate attempt to find fuel, which results in significant weight loss.
Instead, their bodies broke down muscle and fat to compensate for the lack of accessible energy.
11. Frequent Urinary Tract Infections (UTIs)
When your blood sugar is elevated, it creates a prime environment for bacteria to thrive, which increases your risk of infections like UTIs.
Here’s how it works: sugar in your urine can essentially feed bacteria, making it easier for them to multiply and cause infections in your urinary tract.
This higher urine glucose levels can promote bacterial growth, leading to recurrent UTIs.
So, if you’re experiencing these symptoms—like a strong urge to urinate, burning sensation, or cloudy urine—it might be worth checking your blood sugar levels.
Managing your diabetes effectively can help reduce your risk of UTIs and improve your overall urinary health.
12. Digestive Issues
Are you feeling full quickly or having frequent nausea and vomiting?
It might not just be something you ate—it could actually be related to your blood sugar levels, especially if you have diabetes.
High blood sugar can damage the nerves that control digestion, particularly the vagus nerve, leading to conditions like gastroparesis.
The vagus nerve helps regulate the movement of food through your digestive tract. When it’s damaged by high blood sugar levels, your stomach can’t empty properly, causing food to stay in your stomach longer than it should.
This delay in digestion can lead to symptoms like bloating, heartburn, and even episodes of vomiting.
While these symptoms don’t necessarily indicate diabetes, it’s crucial to consult with a healthcare provider for a comprehensive evaluation and appropriate testing.
Early detection and management can also help prevent complications and improve overall health.
How to Support Healthy Blood Sugar Levels
Maintaining healthy blood sugar levels is essential for overall health and well-being, especially for those with diabetes or at risk of developing it.
Here are key strategies to achieve and sustain healthy blood sugar levels:
Balanced Diet
When it comes to supporting healthy blood sugar levels, your diet plays a crucial role.
It’s not just about what you eat, but how you balance your meals.
A balanced diet should include a variety of foods: think vegetables, fruits, whole grains, lean proteins, and healthy fats.
These whole, unprocessed foods provide a steady supply of nutrients without causing rapid spikes in blood sugar levels.
Complex carbs, found in whole grains like brown rice and oats, legumes like beans and lentils, and vegetables like sweet potatoes and spinach, are digested more slowly.
Monitoring portion sizes is also key. Eating smaller, balanced meals and snacks throughout the day can prevent large swings in blood sugar levels.
This approach not only supports stable energy levels but also helps in managing weight—a crucial factor in blood sugar regulation.
High-fiber foods are another ally in this journey. Fruits, vegetables, and whole grains are rich in fiber, which slows down the digestion and absorption of carbohydrates.
This slow release of glucose into the bloodstream helps maintain more consistent blood sugar levels over time.
By incorporating these dietary principles—variety, complex carbohydrates, portion control, and fiber—you can take proactive steps to support healthy blood sugar levels and overall well-being.
Stay Hydrated
Staying hydrated is so important for keeping your blood sugar levels in check.
When you drink enough water, your body functions more efficiently, including how it handles glucose.
Dehydration, on the other hand, can lead to higher blood sugar levels because your body produces less urine.
This reduction in urine production makes it harder for your body to eliminate excess glucose, contributing to spikes in blood sugar.
To support healthy blood sugar levels, it’s essential to limit your intake of sugary drinks.
Beverages like soda, energy drinks, and sweetened coffees can cause rapid spikes in blood sugar due to their high sugar content.
Instead, opt for water, herbal teas, or other low-calorie beverages that won’t cause your blood sugar to skyrocket.
By staying hydrated with the right fluids, you can play an active role in maintaining stable blood sugar levels and supporting your overall health.
Regular Exercise
If you’re looking to support healthy blood sugar levels, regular exercise can make a big difference.
It’s not just about staying fit—it actually helps your body manage glucose more effectively.
When you exercise regularly, like with aerobic activities such as walking or cycling, or strength training like lifting weights, your muscles become more sensitive to insulin.
This means they can absorb glucose from your bloodstream more efficiently, which helps lower your blood sugar levels naturally.
Moreover, exercise directly lowers blood sugar levels by causing muscles to take up glucose for energy.
This action not only helps to bring down immediate blood sugar spikes but also supports overall blood sugar regulation over time.
To get the most out of your exercise routine, aim for at least 150 minutes of moderate-intensity aerobic activity each week.
This could include brisk walking, swimming, or dancing.
Additionally, incorporating muscle-strengthening activities like weightlifting or resistance exercises on two or more days a week can further enhance your blood sugar management.
By making regular exercise a part of your lifestyle, you can support healthy blood sugar levels and improve your overall well-being.
Manage Stress
Managing stress is crucial for keeping your blood sugar levels in a healthy range.
When you’re stressed, your body releases hormones like cortisol and adrenaline, which can cause blood sugar to rise.
To counter this, practicing relaxation techniques such as meditation, yoga, or deep breathing exercises can be really effective.
These activities help calm your mind and body, reducing the production of stress hormones that can spike your blood sugar levels.
Additionally, maintaining a positive outlook and engaging in enjoyable activities can further reduce stress and its impact on blood sugar regulation.
By incorporating these stress management strategies into your daily routine, you can support healthier blood sugar levels and overall well-being.
Taking time for relaxation and positivity isn’t just good for your mental health—it’s also an important part of managing diabetes and maintaining optimal blood sugar control.
Prioritize Good Sleep Hygiene
Getting quality sleep is crucial for keeping your blood sugar levels stable and supporting overall health.
Aim for 7-9 hours of sleep each night to help your body regulate insulin and glucose more effectively.
Establishing a regular sleep schedule is also key.
Going to bed and waking up at the same time each day helps maintain your body’s internal clock, which plays a role in hormone regulation, including those that affect blood sugar.
Research also suggests that irregular sleep patterns can disrupt circadian rhythms, leading to fluctuations in insulin sensitivity and glucose metabolism.
Creating a restful sleep environment can further support healthy blood sugar levels.
Make sure your bedroom is conducive to sleep by keeping it cool, dark, and quiet.
Limiting exposure to screens and blue light from electronic devices before bedtime can also improve sleep quality.
These practices help promote relaxation and signal to your body that it’s time to wind down and prepare for restorative sleep.
By prioritizing good sleep hygiene—like aiming for consistent sleep hours, optimizing your sleep environment, and minimizing disruptions—you can help manage your blood sugar levels more effectively and improve your overall well-being.
Optimize Your NAD Levels
When it comes to supporting healthy blood sugar levels, optimizing your NAD (Nicotinamide Adenine Dinucleotide) levels can be a game-changer.
NAD is a vital coenzyme involved in energy metabolism and cellular function throughout the body.
To naturally boost your NAD levels, incorporate habits like regular exercise and a balanced diet rich in NAD precursors.
Foods like fish, chicken, and avocados are high in niacin, a nutrient that supports NAD production.
Additionally, taking supplements that contain NAD precursors, such as nicotinamide riboside or nicotinamide mononucleotide, may be beneficial under the guidance of a healthcare provider.
How Optimizing NAD Levels Can Help Maintain Healthy Blood Sugar
NAD (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of the body, playing a vital role in various metabolic processes, including the regulation of blood sugar levels.
Here are several ways NAD can help maintain healthy blood sugar levels:
1. Improves Insulin Sensitivity
Optimizing your NAD levels can really make a difference in maintaining healthy blood sugar levels.
NAD is crucial for the activity of sirtuins, a group of proteins known for their role in regulating metabolic processes.
Studies, such as those published in Cell Metabolism, highlight how sirtuins enhance insulin sensitivity—meaning they help cells respond better to insulin, allowing them to absorb glucose more efficiently.
This improved insulin sensitivity can lead to lower blood sugar levels and better overall glucose control.
2. Enhances Mitochondrial Function
Mitochondria are like the powerhouses of our cells, responsible for generating energy that fuels various metabolic processes, including glucose metabolism.
By ensuring adequate NAD levels, you can help support the optimal functioning of mitochondria, which in turn enhances overall metabolism.
This improved mitochondrial function enables the body to efficiently utilize glucose for energy, thereby contributing to better blood sugar regulation.
These processes are fundamental for converting glucose into usable energy within our cells.
NAD also acts as a coenzyme for key enzymes involved in glycolysis, where glucose is broken down to produce energy-rich molecules.
Additionally, NAD is crucial for the Krebs cycle, also known as the citric acid cycle, which further extracts energy from these molecules.
By supporting these metabolic pathways, NAD ensures that glucose is efficiently utilized for energy production rather than accumulating in the bloodstream.
4. Reduces Oxidative Stress
When blood sugar levels are high, it can lead to oxidative stress—a condition where there’s an imbalance between free radicals and antioxidants in the body, resulting in damage to cells and tissues.
NAD acts as a cofactor for these antioxidant enzymes, enhancing their activity to neutralize harmful free radicals generated during high blood sugar conditions.
By reducing oxidative stress, NAD helps maintain the integrity of cells and tissues, mitigating the detrimental effects associated with chronic hyperglycemia, such as diabetic complications.
Research also suggests that supporting NAD levels through dietary sources rich in NAD precursors (like niacin), regular physical activity, and potentially NAD-boosting supplements under medical guidance can enhance antioxidant defense mechanisms.
This, in turn, supports overall cellular health and contributes to better management of blood sugar levels.
By reducing oxidative stress, NAD plays a pivotal role in promoting long-term metabolic health and protecting against diabetes-related complications.
5. Promotes Healthy Inflammatory Response
Optimizing your NAD levels can really help maintain healthy blood sugar levels by promoting a healthy inflammatory response.
When inflammation becomes chronic, it can interfere with insulin signaling, which is crucial for cells to absorb glucose effectively.
It acts as a cofactor for enzymes like SIRT1 and PARPs, which are involved in modulating inflammation.
By supporting these enzymes, NAD helps to balance the body’s inflammatory response, preventing it from becoming excessive or prolonged.
This balanced inflammatory state is essential for maintaining normal insulin function and ensuring that cells respond properly to insulin signals, thereby helping to keep blood sugar levels stable.
6. Aids in DNA Repair
NAD is crucial for the activity of enzymes involved in DNA repair. Maintaining genomic stability is essential for the overall health of metabolic pathways, including those involved in blood sugar regulation.
NAD is essential for the activity of enzymes like PARPs (Poly ADP-ribose polymerases) and SIRT1 (Sirtuin 1), which play critical roles in repairing damaged DNA.
DNA damage can occur due to various factors, including oxidative stress and metabolic dysfunction, which are often associated with high blood sugar levels.
By facilitating DNA repair processes, NAD helps to preserve the integrity of genetic material within cells.
This is crucial for ensuring that metabolic pathways, including those responsible for glucose metabolism and insulin sensitivity, function optimally.
However, NAD depletion or imbalance can impair DNA repair mechanisms, potentially leading to genomic instability and contributing to metabolic disorders such as diabetes.
Furthermore, maintaining a healthy weight is closely tied to better blood sugar control.
Excess weight, especially visceral fat around organs, can lead to insulin resistance and higher blood sugar levels.
By supporting metabolic processes through optimal NAD levels, you can improve energy expenditure and enhance your body’s ability to manage blood sugar effectively.
If you want to support healthy blood sugar levels and reduce the risk of diabetes, it’s crucial to maintain a healthy diet, exercise regularly, and consider taking NAD supplements to optimize your metabolism and overall health.
How can you do it? Here are two ways:
Two Steps to Support Healthy Blood Sugar Levels
Step 1: Order the Intracellular NAD test today.
Order the Intracellular NAD test today and use it as soon as it arrives.
This test can help you determine if you are deficient in NAD, assess the effectiveness of your NAD supplement, and find the optimal dosage for your needs.
Additionally, the test provides actionable data to help you adjust the dosage of Vitality ↑® NAD+ Booster, optimizing your NAD levels and helping you manage chronic fatigue.
This supplement is meticulously formulated to provide a potent blend of natural ingredients that work synergistically to enhance your vitality and combat chronic fatigue.
It is a clinically validated formulation consisting of NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide that work synergistically to help:
Start by using the first Intracellular NAD® test to reveal your current NAD levels. Then, take Vitality ↑® NAD+ Booster for a month.
Afterwards, use the second Intracellular NAD® test to identify your new, optimized levels after taking our NAD supplements. You’ll be pleasantly surprised by how much your levels have improved.
If you’re unsure about what to do or have questions about how to start or interpret your results, you can book your free consultation.
If our Vitality ↑® NAD+ Booster fails to increase your NAD levels, just send us a message within 60 days and we will gladly refund your supplement purchase.
Please note that tests are non-refundable.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.
Fatigue is a common reason for seeking medical care and a source of considerable economic burden.
Just take a look at the graph below:
Among men, the percentage was highest among those aged 18–44 years, followed by those aged 45–64 years, and then those aged 65 years and older (8.9%).
Among women, the decline in the percentage with age was steeper, decreasing from 20.3% to 15.3% (45–64 years) and to 11.5% (65 years and older).
The percentage of adults who felt tired or exhausted most days or every day was higher for women compared with men in each age group.
AND… those who are tired all the time seem to die more likely, as suggested by the lower percentages in those older than 65 years.
There are several reasons why people may experience chronic fatigue. Here are the top three:
3 Major Reasons For Chronic Fatigue
Stress
Stress is a complex phenomenon that can have profound effects on the body, including contributing to the development and exacerbation of chronic fatigue. This is due to several factors:
First, stress activates the HPA axis, leading to the release of cortisol, the body’s primary stress hormone.
Moreover, chronic stress can also lead to alterations in neuroendocrine function, including changes in neurotransmitter levels and receptor sensitivity.
These neuroendocrine changes can affect mood, energy levels, and fatigue.
In conclusion, stress can contribute to chronic fatigue through various mechanisms, including HPA axis dysregulation, inflammation and immune dysregulation, and neuroendocrine changes.
Poor Sleep Quality
Poor sleep quality is a common complaint among people with chronic fatigue and plays a significant role in the development and exacerbation of fatigue.
Research has identified several ways in which poor sleep quality can contribute to chronic fatigue:
Poor sleep quality often manifests as sleep fragmentation, characterized by frequent awakenings throughout the night.
Another way poor sleep quality contributes to chronic fatigue is through alterations in sleep architecture, such as reduced slow-wave sleep and disturbances in rapid eye movement (REM) sleep.
You can also practice good sleep hygiene by sleeping in a cool room and turning off your phone, TV, or any gadgets at least an hour before bedtime to help improve the quality of your sleep.
Low NAD Levels
One often overlooked factor is the role of nicotinamide adenine dinucleotide (NAD) levels in the body.
NAD is a coenzyme found in every cell of the body and plays a crucial role in energy production. It helps convert the food we eat into the energy our cells need to function properly.
When NAD levels are low, our cells may not have enough energy to perform their essential functions, leading to fatigue and other health issues.
Mitochondria are often referred to as the powerhouse of the cell, as they are responsible for producing ATP, the primary source of energy for the body.
When NAD levels are low, mitochondrial function can be compromised, leading to decreased energy production and increased fatigue.
In conclusion, chronic fatigue is a complex condition with various contributing factors.
While stress and poor sleep quality are commonly recognized causes, low NAD levels can also play a significant role.
By optimizing NAD levels through lifestyle changes and supplementation, you may experience improvements in your energy levels and overall quality of life.
Two Steps to Manage Chronic Fatigue
Step 1: Order the Intracellular NAD test today.
Order the Intracellular NAD test today and use it as soon as it arrives. This test can help you determine if you are deficient in NAD, assess the effectiveness of your NAD supplement, and find the optimal dosage for your needs.
Additionally, the test provides actionable data to help you adjust the dosage of Vitality ↑® NAD+ Booster, optimizing your NAD levels and helping you manage chronic fatigue.
This supplement is meticulously formulated to provide a potent blend of natural ingredients that work synergistically to enhance your vitality and combat chronic fatigue.
It is a clinically validated formulation consisting of NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide that work synergistically to help:
Manage fatigue
Boost energy and improve performance
Improve sleep quality
Support inflammation, muscle, and joint pains
Support healthy allergic and asthmatic symptoms
Improve mental clarity and dementia symptoms
Support functions of many organs (liver, kidney, heart, thyroid, fertility)…
But don’t just take our word for it. See how Vitality ↑® NAD+ Booster improved Melissa’s chronic fatigue issues.
I started using this product about 3 weeks ago and I can honestly say that by week 2 the need for a Power Nap daily has decreased, my energy level has increased, and I am exercising more.
Chronic fatigue has been a negative factor in my life since my early 40s so I was willing to give this a try. So far I’m very pleased and I’m only taking 1 scoop a day! Give this product a try
~Melissa
Vitality ↑® NAD+ Booster supports healthy NAD levels to revitalize your cells, optimize your mitochondria, and improve your energy so you can do things you love!
Whether you’re feeling fatigued from a busy lifestyle or struggling with chronic fatigue syndrome,
Vitality ↑® NAD+ Booster can help restore your energy levels and improve your overall well-being.
Start by using the first Intracellular NAD® test to reveal your current NAD levels. Then, take Vitality ↑® NAD+ Booster for a month.
Afterwards, use the second Intracellular NAD® test to identify your new, optimized levels after taking our NAD supplements. You’ll be pleasantly surprised by how much your levels have improved.
If you’re unsure about what to do or have questions about how to start or interpret your results, you can book your free consultation.
If our Vitality ↑® NAD+ Booster fails to increase your NAD levels, just send us a message within 60 days and we will gladly refund your supplement purchase.
Please note that tests are non-refundable.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20.Click here to order.
Imagine a life where simple tasks like tying your shoes or taking a leisurely walk become daunting challenges. This is the reality for millions worldwide struggling with obesity, a condition that not only affects physical health but also imposes significant limitations on everyday life.
Obesity isn’t just about appearance; it’s about a loss of freedom. It’s about the inability to fully engage in activities that bring joy and fulfillment. It’s about the things you can’t do—like comfortably fitting into a movie theater seat, enjoying a hike with friends, or playing with your children without feeling out of breath.
But it’s not just the physical limitations; obesity can also impact mental health, leading to feelings of isolation, low self-esteem, and depression.
In this article, we’ll uncover how NAD can support your weight loss journey and optimize your health.
One aspect of metabolism that significantly impacts weight management is the basal metabolic rate (BMR), which is the amount of energy expended by the body at rest to maintain basic physiological functions.
One of the primary reasons for the decrease in metabolism with age is the loss of muscle mass, known as sarcopenia.
Muscle tissue is metabolically active and requires more energy to maintain than fat tissue.
As muscle mass decreases, the body’s overall energy expenditure decreases, leading to a lower BMR.
Low Estrogen and Testosterone Levels
Hormones play a crucial role in regulating metabolism, appetite, and fat storage in the body. As people age, changes in hormone levels can occur, contributing to weight gain.
In men, testosterone levels naturally decline with age, leading to a decrease in muscle mass and an increase in body fat, especially around the abdomen.
Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme that plays a critical role in various cellular processes, including energy metabolism and DNA repair.
As people age, NAD levels tend to decline, which can have several implications for overall health, including weight gain.
Mitochondria are the powerhouse of the cell, responsible for generating energy in the form of adenosine triphosphate (ATP). NAD is a key player in the electron transport chain, a series of reactions that occur in the mitochondria to produce ATP.
As NAD levels decline with age, mitochondrial function can be impaired, leading to decreased energy production.
This can contribute to a decrease in overall energy expenditure, making it easier to gain weight.
The study found that boosting NAD levels in older mice improved mitochondrial function, increased energy expenditure, and led to a decrease in weight gain compared to control mice.
The mechanism behind these effects involves the role of NAD in regulating sirtuins, a class of proteins that play a role in regulating cellular processes related to aging and metabolism.
Increasing NAD levels in the body has been shown to have several benefits related to fat burning and weight loss.
Improved Metabolic Function
NAD is involved in several metabolic pathways, including the breakdown of fats (lipolysis) for energy. By increasing NAD levels, the body may be able to more efficiently convert stored fat into energy, potentially leading to weight loss.
NAD is involved in DNA repair and cellular maintenance processes. By supporting these functions, NAD may help optimize cellular health, which is important for overall metabolic function and weight management.
Potential Appetite Regulation
Some studies suggest that NAD may play a role in appetite regulation. By influencing signaling pathways involved in hunger and satiety, NAD may help reduce calorie intake, supporting weight loss.
This only shows that NAD shows promise as a potential aid in fat burning and weight loss by improving metabolic function, increasing energy expenditure, and supporting overall cellular health.
For supporting healthy NAD levels and achieving your weight loss goals, Vitality ↑® NAD+ Booster stands as our trusted choice in NAD supplementation.
For better results, it’s best to check your NAD levels with our Intracellular NAD test to determine if they are within the normal range, low, or high. This information can help you adjust the amount of Vitality ↑® NAD+ Booster to take for optimal results.
Ready to lose weight and trim off stubborn fats?
Your Next Steps…
Step 1: Order the Intracellular NAD test today.
Order the Intracellular NAD test today and use it as soon as it arrives. This test can help you determine if you are deficient in NAD, assess the effectiveness of your NAD supplement, and find the optimal dosage for your needs.
Additionally, the test provides actionable data to help you adjust the dosage of Vitality ↑® NAD+ Booster, optimizing your NAD levels and help you lose weight.
This clinically validated formulation includes NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide, which synergistically work to:
Revitalize your cells
Optimize your mitochondria
Manage your appetite
Help you burn fat fast, , just like Anna…
A Doctor friend in South America asked me order and take this to him. After reading about it and him speaking of his results I have ordered for my Family too. We are all using it and seeing results.
It is helping me with fatigue, weight loss and over eating. I am finally able to try and diet.
Great product and easy to take. I am also having my daughter with Asthma and fibro take it and she is feeling better.
Start by using the first Intracellular NAD® test to reveal your current NAD levels. Then, take Vitality ↑® NAD+ Booster for a month.
Afterwards, use the second Intracellular NAD® test to identify your new, optimized levels after taking our NAD supplements. You’ll be pleasantly surprised by how much your levels have improved.
If you’re unsure about what to do or have questions about how to start or interpret your results, you can book your free consultation.
If our Vitality ↑® NAD+ Booster fails to increase your NAD levels within 60 days, we will gladly refund your supplement purchase. Please note that tests are non-refundable.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20.Click here to order.
As women age, menopause can bring about significant changes, including shifts in sexual desire and satisfaction.
For many, this transition can be challenging, affecting not only their own sense of self but also their relationships. It’s not uncommon to feel like your sex life is over, especially when faced with a loss of libido and arousal.
Take the experience of Jane (not her real name), a 60-year-old woman who has been struggling with a challenging menopause.
Like many women in her situation, Jane’s sexual appetite has diminished, leaving her feeling like there’s nothing to miss. Despite having a loving and understanding husband, the lack of intimacy has started to take a toll on their relationship.
While she tries to accommodate her husband’s needs, the situation has become increasingly difficult for both of them.
Jane’s story is not uncommon. Many men and women experience a decline in libido and arousal as they age, impacting their relationships and overall well-being.
This decline can lead to feelings of inadequacy, low self-esteem, and even a sense of loss in the relationship.
Why does this happen? Why do you lose intimacy and sex drive as you age? Here are three science-backed reasons why.
In this article, we talk about…
The top three reasons for the loss of libido in women that you should be aware of.
The significant impact of low NAD levels on your sexual health, including reduced energy and hormonal imbalances.
How boosting NAD levels can reignite your passion and spice up your sex life, leading to a more fulfilling and intimate connection.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.
3 Reasons for the Loss of Libido in Women
Hormonal Changes
Hormonal changes, especially during menopause, can have a profound impact on female libido.
Women produce testosterone in their ovaries and adrenal glands, and a decline in testosterone levels can lead to a decrease in sexual desire and arousal.
A study published in the Journal of Clinical Endocrinology & Metabolism investigated the effects of testosterone therapy on postmenopausal women with low libido.
Overall, the hormonal changes that occur during menopause can have a profound impact on female sexual function, underscoring the importance of addressing these hormonal imbalances in managing low libido.
Stress and Fatigue
High levels of stress and fatigue can significantly affect a woman’s libido.
The demands of daily life, including work, family responsibilities, and other stressors, can lead to increased levels of cortisol, the primary stress hormone.
This state can negatively affect cellular function and contribute to age-related health issues, including reduced energy levels and potentially, decreased libido.
These studies suggest that maintaining optimal NAD+ levels may play a role in supporting overall health, including sexual health and libido, especially as individuals age and NAD+ levels naturally decline.
Here at Jinfiniti, we have found that customers who consistently use Vitality ↑® NAD+ Booster experience significant improvements in their sex drive and function.
In fact, many have been able to rekindle the intimacy they once lost with their partners by adding Vitality ↑® NAD+ Booster to their daily routine.
How NAD Can Boost Your Libido
Increased Energy Levels
NAD+ is a crucial coenzyme involved in cellular energy production and plays a key role in regulating various cellular processes, including metabolism and DNA repair.
As we age, NAD+ levels naturally decline, which can lead to a decline in cellular function and contribute to age-related health issues, including decreased libido and sexual function.
Supplementation with NAD+ precursors, has been shown to increase NAD+ levels in cells.
By improving cellular energy production and overall cellular function, NAD+ supplementation may help improve energy levels, mood, and vitality, all of which are important factors in sexual desire and activity.
Neurotransmitters are chemical messengers in the brain that play a crucial role in regulating various bodily functions, including mood, stress response, and sexual function.
Dopamine, serotonin, and norepinephrine are neurotransmitters that are particularly important for sexual desire and arousal.
Low levels of serotonin have been associated with an increase in impulsive behaviors, including those related to sexual activity.
On the other hand, high levels of serotonin can lead to a decrease in sexual desire and arousal. Maintaining optimal serotonin levels is important for a healthy sex drive.
By supporting NAD+ levels, supplementation may help maintain optimal neurotransmitter function, which can have a positive impact on sexual desire and arousal, as mood plays a significant role in sexual health and satisfaction.
Enhanced Cellular Function
NAD is essential for maintaining healthy cellular function.
By supporting cellular health, NAD supplementation may help improve overall bodily functions, including those related to sexual health. This can result in enhanced libido and sexual function.
Mitochondria, often referred to as the “powerhouses” of the cell, are responsible for producing the energy (ATP) needed for cellular function.
By improving mitochondrial function, NAD+ supplementation may help enhance overall cellular function, including those related to sexual health.
This can result in improved libido and sexual function, highlighting the potential benefits of NAD+ supplementation for sexual health and vitality.
As women age, NAD levels tend to decline, leading to mitochondrial dysfunction and reduced energy production.
This decline in mitochondrial function can affect various bodily functions, including those related to sexual health.
By improving mitochondrial function through NAD supplementation, women may experience increased energy levels, which can positively impact libido and sexual desire.
In conclusion, menopause and aging can bring about changes in your sex life, but it doesn’t have to mean the end of intimacy.
By communicating openly with your partner, prioritizing self-care, and considering supplements like NAD from Jinfiniti, you can take proactive steps to boost your libido and reignite the spark in your relationship.
Two Steps to Boost Your Libido
Step 1: Test Your NAD levels
Is your NAD levels low, borderline, or high?
The Intracellular NAD® Test is the first and only NAD test that can help you determine if you are deficient in NAD, if your NAD supplement is working, or if you are taking the optimal dosage for your supplement.
This test provides you with the information you need to optimize your NAD levels without the guessing game.
Moreover, it gives you actionable data to help you find an effective and affordable product and the correct dosage to optimize your NAD level.
Vitality ↑® NAD+ Booster is a clinically validated formulation consisting of NAD precursor, Creatine monohydrate, D-Ribose, and Nicotinamide that work synergistically to help:
Boost energy and improve performance
Improve sleep quality
Support inflammation, muscle, and joint pains
Support healthy allergic and asthmatic symptoms
Improve mental clarity and dementia symptoms
Support functions of many organs (liver, kidney, heart, thyroid, fertility)…
This supplement supports healthy NAD levels to revitalize your cells, optimize your mitochondria, and boost your libido so you can perform in bed with your partner.
Remember: reaching menopause isn’t the end of your sex life.
You can always boost your libido and sex drive with the help of NAD supplementation, along with a healthy diet and exercise.
You can also take advantage of the NAD Optimization® Bundles, where you can get 2 Intracellular NAD® tests and 1 Vitality ↑® NAD+ Booster supplement — and get one free supplement and free consultation.
This package allows you to reveal your current NAD level, the optimal dosage for NAD+ precursor supplements, and health benefits from optimized NAD levels.
If you want to improve your sex drive and libido even as you age…
Aging is a natural process that all living organisms experience. As you age, your body undergoes a series of changes that can impact your health and quality of life. To better understand these changes, scientists have identified nine fundamental hallmarks of aging. These hallmarks provide valuable insights into the underlying mechanisms of aging and offer potential targets for interventions to promote healthy aging.
“Intrinsic aging is due to genetic factors, while extrinsic aging can be attributed to lifestyle choices like alcohol consumption, smoking, diet, exercise and stress management.” Dr. Neil Paulvin, Regenerative Medicine Doctor
The Science Behind Aging
Aging is a complex and multifactorial process influenced by a combination of genetic and environmental factors. At the cellular level, aging is characterized by a gradual decline in the function of various biological processes. Understanding the biological mechanisms of aging is crucial for developing strategies to mitigate its negative effects.
Aging is not a simple linear process; rather, it involves a progressive decline in the ability of cells, tissues, and organs to maintain physiological homeostasis. This decline is influenced by a range of factors, including DNA damage, protein dysfunction, and cellular senescence. Over time, these cellular changes can lead to the development of age-related diseases.
One of the key factors contributing to aging is DNA damage. With age, the DNA becomes more susceptible to damage from various sources, such as environmental toxins, radiation, and oxidative stress. This damage can result in mutations and errors in DNA replication, leading to cellular dysfunction and ultimately contributing to aging.
Another important aspect of aging is protein dysfunction. Proteins are essential for the proper functioning of cells, and their misfolding or aggregation can have detrimental effects. As you age, the quality control mechanisms responsible for maintaining proper protein folding and function become less efficient, leading to the accumulation of damaged proteins. This protein accumulation can disrupt cellular processes and contribute to the overall decline in cellular function associated with aging.
Cellular senescence is also a significant contributor to the aging process. Senescence refers to a state in which cells lose their ability to divide and function properly. This can occur due to various factors, including DNA damage, telomere shortening, and cellular stress. Senescent cells can accumulate in tissues over time, secreting harmful molecules that can promote inflammation and tissue dysfunction. The presence of senescent cells has been linked to age-related diseases and overall aging.
The Role of Genetics in Aging
Genetics plays a significant role in determining an individual’s rate of aging. Certain genes have been identified as key regulators of the aging process. For example, variations in genes involved in DNA repair mechanisms can impact an individual’s susceptibility to age-related diseases.
One such gene is the tumor suppressor gene p53, which plays a crucial role in DNA repair and cell cycle regulation. Mutations in the p53 gene can impair its function, leading to an increased risk of DNA damage accumulation and accelerated aging. On the other hand, certain genetic variations in genes involved in antioxidant defense mechanisms, such as the superoxide dismutase gene, have been associated with increased longevity and reduced risk of age-related diseases.
It is important to note that while genetics can influence the rate of aging, it is not the sole determinant. Environmental factors also play a significant role in the aging process.
Environmental Factors Influencing Aging
In addition to genetics, environmental factors also contribute to the aging process. Factors such as diet, exercise, and exposure to toxins can modulate the rate of aging.
Dietary choices have a profound impact on aging. A diet rich in fruits, vegetables, whole grains, and lean proteins provides essential nutrients and antioxidants that can help protect against cellular damage and promote healthy aging. On the other hand, a diet high in processed foods, saturated fats, and sugar can contribute to inflammation, oxidative stress, and accelerated aging.
Regular physical activity is another crucial factor in healthy aging. Exercise has been shown to have numerous benefits, including improved cardiovascular health, enhanced cognitive function, and reduced risk of age-related diseases. Exercise can also stimulate the production of growth factors and hormones that promote cellular repair and regeneration.
Exposure to toxins and pollutants in the environment can also accelerate the aging process. Air pollution, cigarette smoke, and certain chemicals can induce oxidative stress and inflammation, leading to cellular damage and premature aging. Minimizing exposure to these harmful substances and adopting protective measures, such as wearing sunscreen and avoiding smoking, can help mitigate their negative effects on aging.
In conclusion, aging is a complex process influenced by a combination of genetic and environmental factors. Understanding the biological mechanisms of aging and the role of genetics and environmental factors is crucial for developing strategies to promote healthy aging and mitigate the negative effects of aging-related diseases.
The Nine Hallmarks of Aging
Scientists have identified nine hallmarks that contribute to the aging process. These hallmarks encompass a range of cellular and molecular changes that occur during aging.
Understanding these hallmarks is crucial for developing interventions that can slow down or reverse the aging process, ultimately improving health and extending lifespan.
1. Genomic Instability
Genomic instability refers to the increased susceptibility of DNA to damage and mutation. As we age, our DNA becomes more prone to errors and breaks, leading to genomic instability. This instability can result in the accumulation of genetic mutations, contributing to the development of age-related diseases, such as cancer.
Various factors, including exposure to environmental toxins, radiation, and oxidative stress, can cause genomic instability. These factors can induce DNA damage and impair the repair mechanisms, leading to the accumulation of mutations over time.
2. Telomere Attrition
Telomeres are protective caps at the ends of chromosomes that shorten with each cell division. Telomere attrition is a hallmark of aging, as the progressive shortening of telomeres limits the replicative capacity of cells. Ultimately, this can lead to cellular senescence and tissue deterioration.
During cell division, the enzyme telomerase adds repetitive DNA sequences to the telomeres, counteracting the shortening process. However, telomerase activity is low in most somatic cells, resulting in gradual telomere attrition over time.
Shortened telomeres can trigger DNA damage responses and cellular senescence, limiting the regenerative potential of tissues and contributing to age-related diseases.
3. Epigenetic Alterations
Epigenetic alterations are changes in gene expression patterns that do not involve changes to the underlying DNA sequence. Epigenetic modifications can accumulate over time and impact gene regulation. These alterations can influence the aging process by altering the expression of genes involved in various cellular functions.
Epigenetic modifications, such as DNA methylation, histone modifications, and non-coding RNA molecules, play a crucial role in regulating gene expression. With aging, there is a progressive alteration in the epigenetic landscape, leading to changes in gene expression patterns. These epigenetic changes can affect cellular processes, including DNA repair, inflammation, and cellular senescence, contributing to the aging phenotype and age-related diseases.
4. Loss of Proteostasis
Proteostasis refers to the cellular mechanisms responsible for maintaining protein homeostasis. With aging, there is a decline in the ability of cells to properly fold and degrade proteins. This can lead to the accumulation of misfolded proteins, which are associated with the onset of neurodegenerative diseases.
Protein quality control systems, including chaperones and proteases, help maintain the proper folding and degradation of proteins. However, with age, these systems become less efficient, leading to the accumulation of misfolded or aggregated proteins.
The accumulation of misfolded proteins can disrupt cellular function and promote the formation of toxic protein aggregates, contributing to age-related neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease.
5. Deregulated Nutrient Sensing
The body’s ability to sense and respond to changes in nutrient availability is crucial for maintaining metabolic homeostasis. During aging, there is a dysregulation in nutrient-sensing pathways, such as insulin and mTOR signaling. These alterations can contribute to metabolic dysfunction and age-related diseases, including diabetes.
Nutrient sensing pathways are vital in coordinating cellular responses to nutrient availability. Insulin signaling, for example, regulates glucose uptake and metabolism, while mTOR signaling controls protein synthesis and cell growth.
With aging, these nutrient-sensing pathways become dysregulated, leading to impaired glucose metabolism, increased insulin resistance, and altered protein synthesis. These changes can contribute to metabolic disorders and age-related diseases, such as type 2 diabetes and cardiovascular diseases.
6. Mitochondrial Dysfunction
Mitochondria are the powerhouses of our cells, responsible for producing energy in the form of adenosine triphosphate (ATP). With aging, mitochondrial function declines, leading to decreased energy production and increased production of reactive oxygen species (ROS). This mitochondrial dysfunction can contribute to cellular damage and aging-associated diseases.
Mitochondrial dysfunction can occur due to various factors, including oxidative stress, mitochondrial DNA mutations, and impaired mitochondrial biogenesis. These factors can disrupt the electron transport chain and impair ATP production.
Furthermore, dysfunctional mitochondria produce higher levels of ROS, which can damage cellular components, including DNA, proteins, and lipids. This oxidative damage can contribute to cellular senescence and the development of age-related diseases, such as cardiovascular disease and neurodegenerative disorders.
7. Cellular Senescence
Cellular senescence is a state in which cells lose their ability to divide and function properly. Senescent cells accumulate with age and secrete pro-inflammatory molecules, a phenomenon known as the senescence-associated secretory phenotype (SASP). The accumulation of senescent cells and the associated inflammation contribute to tissue dysfunction and age-related pathologies.
Various factors, including DNA damage, telomere attrition, and oncogene activation can trigger cellular senescence. Once senescence is induced, cells enter a state of irreversible growth arrest. Senescent cells secrete a variety of pro-inflammatory molecules, such as cytokines, chemokines, and growth factors. This SASP can promote chronic inflammation, disrupt tissue homeostasis, and contribute to the development of age-related diseases, including cancer, cardiovascular disease, and neurodegenerative disorders.
8. Stem Cell Exhaustion
Stem cells are responsible for tissue regeneration and repair. However, with aging, the regenerative capacity of stem cells declines. This is due to a combination of factors, including changes in their microenvironment and the accumulation of DNA damage. Stem cell exhaustion can impair tissue repair and increase the risk of age-related diseases.
Stem cells reside in specialized niches within tissues and can differentiate into various cell types. They play a crucial role in tissue homeostasis and repair by replenishing damaged or lost cells. With aging, the stem cell niche changes, leading to a decline in stem cell function. Additionally, stem cells can accumulate DNA damage over time, impairing their regenerative potential.
These changes result in reduced tissue repair and regeneration, contributing to age-related diseases, such as impaired wound healing, muscle loss, and degenerative conditions.
9. Altered Intercellular Communication
Effective communication between cells is essential for maintaining tissue homeostasis. During aging, there is a disruption in intercellular communication, leading to chronic inflammation and the impaired functioning of tissues. This altered communication can contribute to the development of age-related diseases, such as Alzheimer’s disease.
Cells communicate with each other through various signaling pathways, including direct cell-to-cell contact and the release of signaling molecules, such as cytokines and growth factors.
With aging, there is a dysregulation in intercellular communication, leading to chronic low-grade inflammation, often referred to as inflammation. This chronic inflammation can contribute to tissue dysfunction and the development of age-related diseases, including neurodegenerative disorders like Alzheimer’s disease.
Understanding and targeting the mechanisms underlying altered intercellular communication may offer potential therapeutic strategies for mitigating age-related pathologies.
Fitness and physical activity extends our longevity
The Impact of Aging on the Human Body
Aging and the Cardiovascular System
Aging is associated with structural and functional changes in the cardiovascular system. As you age, blood vessels become stiffer and less elastic, increasing the risk of hypertension and cardiovascular disease. Additionally, the heart muscle changes, leading to decreased cardiac output and increased susceptibility to heart failure.
Aging and the Nervous System
The aging process affects the nervous system, leading to various cognitive and motor changes. Age-related neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, are characterized by the accumulation of protein aggregates and the degeneration of specific neuronal populations. These diseases can significantly impact an individual’s quality of life.
Aging and the Musculoskeletal System
With aging, there is a gradual loss of muscle mass and strength, a condition known as sarcopenia. This loss of muscle mass can affect mobility and increase the risk of falls and fractures. Additionally, aging is associated with changes in bone density, leading to an increased risk of osteoporosis.
Aging and the Digestive System
The digestive system undergoes age-related changes that can impact nutrient absorption and gastrointestinal motility. Aging can lead to a decrease in the production of digestive enzymes, making it more challenging to digest certain foods. These changes can contribute to gastrointestinal disorders, including constipation and malnutrition.
Conclusion
The nine fundamental hallmarks of aging provide valuable insights into the biological processes underlying aging. Understanding these hallmarks can help researchers develop strategies to promote healthy aging and mitigate the negative effects of aging. By adopting a holistic approach that addresses both genetic and environmental factors, you can strive to age gracefully and maintain your health and well-being as you grow older. Extend your health span by increasing your NAD+ levels with Accuri® Vitality ↑® NAD+ Booster by Jinfiniti.
Lastly, if you’re interested in going deeper into health-related content, here are a few of our recent posts that you may want to read:
P.S. Want to boost your intracellular NAD levels? Try a 2 week trial of our Jinfiniti Vitality ↑® NAD+ Booster (do 2 scoops per day), use the discount code Blog15 if you’re a new customer for 15% off your 1st order)
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20.Click here to order.
There’s nothing worse than a heavy case of brain fog to keep you from doing everything you need to do and accomplishing everything you need to accomplish.
While brain fog can have many causes, the good news is that we’ve uncovered solutions capable of clearing it in as little as two weeks.
In this article, we talk about…
The hidden culprits behind brain fog and what they’re doing to your mind.
Powerful, natural strategies to banish brain fog and supercharge your memory.
How NAD can sharpen your brain and enhance your memory in just two weeks or less.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.
Candida
There’s no way around it: candida is an ugly main player when it comes to brain fog. Candida overgrowth, especially in your gut, could be the prime culprit behind those foggy moments in your head.
When candida levels take over your microbiome, it not only messes with your gut’s balance, it also causes inflammation and releases toxins like acetaldehyde into your system. This inflammation can then spread to your brain, leading to trouble concentrating and causing you to feel mentally foggy.
According to the Mitchell Medical Group, one in three Americans suffer from a serious candida overgrowth, leading to a variety of health issues, from mild infections to serious neurological diseases.
Interestingly enough, most candida overgrowth is caused by the same things that we talk about here at Jinfiniti quite a bit: things that can shorten your lifespan, silently trigger disease, and prevent you from the energy and vitality you desire.
What are those things, you ask? Here are the big ones:
Low metabolic health
Sugar
Stress
Microbiome imbalance
Low NAD Levels
Let’s dive into how low levels of NAD (nicotinamide adenine dinucleotide) might be linked to brain fog. NAD is the MVP of your body’s energy production, helping to convert food into energy that your cells can use.
But as many of us already know, our NAD plus levels naturally decline, and certain lifestyle factors like poor diet, lack of exercise, and chronic stress can speed up this process.
When your NAD+ levels dip too low, it can throw a wrench into your body’s energy production, leaving you feeling sluggish and mentally foggy.
But that’s not all –specifically when it comes to brain fog, NAD plays a crucial role in maintaining the health of your neurons, the cells in your brain that transmit signals.
When NAD levels are low, it can lead to oxidative stress and inflammation in the brain, which can interfere with communication between neurons and impair cognitive function. This can manifest as difficulty concentrating, memory problems, and the frustrating feeling of brain fog.
Limited Exercise
Let’s talk about how skipping those workouts can leave you feeling a bit foggy in the brain department.
When you don’t exercise enough, your body misses out on all those feel-good chemicals like endorphins and dopamine that get released during physical activity.
These chemicals not only boost your mood but also help improve blood flow to your brain, delivering oxygen and nutrients that keep your noggin sharp.
Plus, regular exercise has been shown to reduce inflammation and oxidative stress in the brain, which can contribute to that foggy feeling when left unchecked.
So in order to keep your brain clear and focused, make time for even a little bit of movement each day, even if it’s just a walk around the block or a quick yoga session.
Some other causes of brain fog to consider:
Processed foods
Hormone imbalance
Sleep
Neuro or brain inflammation
Infections
Iron deficiency (especially in women, but get your levels checked before getting on a supplement)
B vitamins deficiency
How to Eliminate Brain Fog
Below are simple, natural ways to banish brain fog and enhance your memory and mental health.
Diet
First off, make some tweaks to your diet. Focus on eating whole foods like fruits, veggies and clean proteins. Cut back or eliminate sugar and simple carbohydrates.
These dietary changes can help stabilize your blood sugar levels and prevent energy crashes that contribute to brain fog.
Sleep
Sleep acts as a crucial reset mechanism for the brain, facilitating memory consolidation, information processing, and the removal of toxins accumulated throughout the day. Getting enough sleep is crucial for cognitive function, so aim for 7-9 hours of shut-eye each night.
And while we’re on the topic of relaxation, managing stress is key too. Whether it’s through meditation, deep breathing exercises, or simply taking some time to unwind with a good book, finding ways to de-stress can help clear your mind and banish brain fog.
Supplements
Supplements like omega-3 fatty acids, vitamin B12, and certain herbs like ginkgo biloba and bacopa monnieri have been studied for their potential to improve memory and concentration, and have been linked to overall cognitive performance. As I stated above, hormone treatments may also be helpful if your levels are low.
NAD
NAD (nicotinamide adenine dinucleotide) is a total game-changer in combating brain fog because it is a powerhouse molecule that plays a vital role in cellular energy production and maintaining the health of neurons in the brain.
When NAD levels are sufficient, they support optimal mitochondrial function, ensuring that your brain cells have the energy they need to function efficiently.
NAD also acts as a cofactor for various enzymes involved in DNA repair, stress response, and cell signaling pathways crucial for maintaining cognitive function.
NAD not only fights brain fog, it prevents brain fog from even happening in the first place. NAD helps protect neurons from damage and promotes overall brain health by scavenging free radicals and reducing inflammation.
And if you happen to be 50+ years old, your NAD levels are likely not optimal unless you’ve been taking our Vitality ↑® NAD+ Booster for quite some time. According to extensive research, the average healthy 50-year-old has already lost 50% of their NAD levels.
At Jinfiniti, our flagship NAD supplement, the Vitality ↑® NAD+ Booster, is a patent-pending formulation that has been extensively tested in clinical studies by hundreds of clinics and by thousands of consumers. It allows optimization of NAD in approximately 90% of users, a figure incomparable to any other NAD supplementation on the market.
No other molecule comes close to helping your cells function optimally as much as NAD.
This means that pain, inflammation, fatigue, and brain fog all decrease while mental clarity, stamina, recovery, energy, youthfulness, and vitality all increase when NAD is optimized.
So here’s your reminder to restock on your Vitality ↑® NAD+ Booster. Don’t forget that our subscription option is always the best deal and will keep you from running out.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.
No other molecule is as vital to optimal cellular function as NAD+.
While it’s well-known that NAD+ can reduce pain, inflammation, and fatigue while boosting mental clarity, stamina, recovery, energy, and youthfulness, there’s even more to its benefits than meets the eye.
In this article, we’ll talk about the 9 benefits of optimizing your NAD levels at the cellular level.
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20. Click here to order.
NAD is arguably the foundational molecule for all of life.
Sadly, it declines as we age, but we can bring our NAD levels back to levels most of us haven’t experienced since we were teenagers, thus giving us a trickle-down effect for many of our age-related diseases (see graph below).
If you’re into health, peak performance, biohacking, or you’re just interested in feeling great, what I’m sharing today is relevant for you. Let’s dive into the cellular functions impacted by NAD.
9 Powerful Benefits of Optimizing Your NAD Levels
1. Telomere Shortening
Telomere shortening and NAD+ levels are intricately connected in the context of cellular aging and health.
Telomeres are the protective caps at the end of our chromosomes, and their gradual shortening over time is a hallmark of the aging process.
As telomeres shorten, cells may lose their ability to divide and function properly.
NAD+ plays a crucial role in this process by supporting the activity of enzymes called sirtuins, which are involved in DNA repair and maintenance.
Sirtuins require NAD+ as a coenzyme to function effectively, and a decline in NAD+ levels can impair their ability to promote telomere stability and repair.
2. Deregulated Nutrient Sensing
Deregulated nutrient sensing and NAD+ levels are closely intertwined in the context of metabolic health and aging.
NAD+ serves as a critical cofactor of enzymes like sirtuins (sirtuins + NAD are intricately connected to many aspects of aging), which are key regulators of nutrient-sensing pathways.
When nutrient sensing becomes dysregulated, often due to overnutrition and sedentary lifestyles, it can lead to metabolic dysfunction and age-related diseases.
Maintaining adequate NAD plus levels is crucial to support sirtuin activity and restore balance in nutrient sensing.
3. Stem Cell Exhaustion
Stem cell exhaustion and NAD+ levels are intimately interconnected in the context of aging and tissue homeostasis.
Stem cells are essential for the regeneration and repair of various tissues, and their capacity to divide and differentiate declines with age.
NAD plays a pivotal role in maintaining stem cell function by supporting critical processes like DNA repair and energy production.
When NAD levels are low, it contributes to reduced sirtuin activity, leading to inefficient DNA repair and genomic instability within stem cells, which in turn accelerates stem cell exhaustion and compromises tissue repair.
By bolstering your NAD levels, it’s possible to enhance sirtuin function and potentially rejuvenate stem cell activity.
4. Disabled Microautophagy
Disabled microautophagy and NAD levels are intricately related in the context of cellular quality control and overall health.
Microautophagy is a cellular process responsible for degrading and recycling damaged organelles and proteins through direct engulfment by lysosomes.
NAD+ plays a crucial role in regulating the activity of sirtuins, which are involved in the maintenance of cellular quality control mechanisms, including autophagy.
When NAD levels decline, sirtuin activity may be compromised, impacting microautophagy and other autophagic processes.
This can result in the accumulation of cellular debris, and impaired organelle quality, and ultimately contribute to cellular dysfunction and aging.
By sustaining optimal NAD levels, it may be possible to support the efficient functioning of microautophagy and maintain cellular health, offering potential benefits for overall well-being and longevity.
5. Inflammaging
Inflammaging, the chronic low-grade inflammation that accompanies the aging process, is closely intertwined with NAD levels in the context of immune function and age-related diseases.
NAD is a critical cofactor for enzymes known as sirtuins, which play a pivotal role in regulating inflammation and immune responses.
As NAD+ levels naturally decline with age, sirtuin activity may decrease, leading to a state of chronic inflammation.
This persistent low-grade inflammation is associated with a range of age-related conditions, including neurodegenerative diseases, cardiovascular issues, and metabolic disorders.
By replenishing NAD levels, it is possible to potentially enhance sirtuin-mediated anti-inflammatory mechanisms and mitigate inflammaging, offering a promising approach to promote healthier aging and reduce the risk of age-related diseases.
6. Mitochondrial Dysfunction
Mitochondrial dysfunction and NAD levels are intricately linked in the realm of cellular energy production and overall health.
Mitochondria are the powerhouse of our cells, responsible for generating ATP, the cellular energy currency.
NAD plays a critical role as a coenzyme in the electron transport chain, a fundamental process in mitochondrial ATP synthesis.
However, as NAD levels decline with age, the efficiency of mitochondrial function may deteriorate, leading to impaired energy production and an increase in oxidative stress.
By maintaining optimal NAD levels, it’s possible to support the function of key enzymes involved in mitochondrial energy production, potentially mitigating mitochondrial dysfunction, and promoting cellular vitality, which is crucial for overall health and longevity.
7. Cellular Senescence
Cellular senescence and NAD levels are interconnected in the context of aging and tissue function.
Cellular senescence is a state where cells lose their ability to divide and function properly, often as a response to various stressors or DNA damage contributing to aging-related diseases and tissue dysfunction.
Sirtuins, play a crucial role in regulating and controlling the process of senescence.
Declining NAD levels with age can impair sirtuin function, potentially promoting the accumulation of senescent cells in tissues. These senescent cells release proinflammatory signals.
8. Loss of Proteostasis
Loss of proteostasis, the failure to maintain the correct balance of properly folded and functional proteins, is intricately connected with NAD+ levels in the context of cellular health and aging.
NAD is essential for the activity of sirtuins so by replenishing NAD levels, it may be possible to enhance sirtuin-mediated protein quality control mechanisms and maintain proteostasis, potentially mitigating age-related protein aggregation and related diseases, thus supporting overall cellular health.
9. Altered Cellular Communication
Altered cellular communication and NAD levels are closely linked in the context of aging and age-related diseases. NAD plays a pivotal role in the regulation of intercellular signaling and communication processes.
As NAD levels naturally decline with age, sirtuin activity may diminish, disrupting the finely tuned cellular communication network.
By maintaining optimal NAD levels, it is possible to support sirtuin-mediated mechanisms that help restore proper cellular communication and signaling pathways, potentially mitigating age-related cellular dysfunction and promoting healthier aging.
Lastly, if you’re interested in going deeper into health-related content, here are a few of our recent posts that you may want to read:
If you can slow your aging, can you delay disease? If you delay disease, can you can delay death?
“The loss of NAD as we age, and the resulting decline in sirtuin activity, is thought to be a primary reason our bodies develop diseases when we are old, but not when we are young.”
-Dr. David Sinclair, Harvard Medical School, Lifespan
It’s the supposed, inevitable decline that will swallow each and every one of us. Or will it?
Have you ever noticed that some people display vastly different health statuses, sometimes even in the same family?
Prominent researchers in the last few decades have come to cautiously agree to a rough consensus of aging hallmarks. While it is very debatable how many hallmarks there are, I believe that these six are the primary hallmarks of aging as the others can be traced back to these six core hallmarks in one form or another.
The six core reasons of aging are as follows:
1. NAD and Other Micronutrient Deficiencies
Since NAD arguably acts as the most important enzyme in your body and is such a foundational building block of nearly every cellular process, it’s vital to keep your NAD levels optimal to slow the tides of aging.
Unfortunately, the average adult is heading towards a significant NAD deficiency by their early 40s. But thankfully, with our patent-pending Vitality boost, the most effective NAD-optimizing supplement ever developed, you can boost your NAD levels to optimal as fast as a couple weeks (did you see Doc Jen’s results?).
2. Oxidative Stress and DNA Damage
When human cells experience oxidative stress, it’s the equivalent of a Roman army putting down its shields and turning their backs on the attackers as they attack. Since your cells always have attackers swimming around in the bloodstream, when they let their guard down due to fatigue (hint: NAD deficiency is the primary cause of this) the DNA goes under attack.
When your cells are too tired to fight the invaders, they lose their DNA and aging accelerates, plus, cells with broken DNA that continue to multiply can form tumors.
3. Glycation and Blood Sugar
When your levels of insulin resistance increase, it’s because your cells have experienced an overwhelming amount of glucose and fructose pulsating through your bloodstream. And when that happens, your cells begin to brown, like the sugar crumbles on top of creme brûlée.
This is a process called glycation.
In other words,you don’t want his happening to your cells. I don’t know about you, but burnt cells don’t sound very enticing to me.
4. Chronic Inflammation
Foreign invaders (e.g., viruses and bacteria) damage cells directly, so our bodies have developed an inflammatory response, which recruits white blood cells to release toxins like oxygen radicals and cytokines (peptides with killing activity) to destroy the invaders.
Inflammatory responses are meant to be temporary, but unfortunately there are complications when you’re perpetually living in an inflamed state, like one the average American lives in.
Normal tissues can experience long term damage from an inflammatory response; your tissues can also be mistaken for a foreign invader (e.g. kidney disease), and a prolonged bad bacterial overgrowth in the gut can lead to breaks in the intestinal barrier (e.g. leaky gut). Inflammation is good in the short run, but awful for you in the long run.
5. Cellular Senescence
When your cells don’t function properly, some of them have the potential to turn into what we like to call zombie cells. Zombie cells are old cells that refuse to die; but not only that, they also travel in your blood and damage healthy cells, spreading toxicity and inflammatory proteins.
If your body is functioning properly, it’s designed to get rid of zombie cells. If not, your disease chances and illness symptoms will only increase as you age.
6. Metabolic Dysfunction
Nicotinamide adenine dinucleotide or NAD is central to the regulation of cellular energy production, but inadequate NAD levels can impede energy-producing pathways and result in reduced cellular energy production, contributing to conditions like metabolic syndrome.
And what is metabolic syndrome? Metabolic syndrome is a cluster of conditions stemming from metabolic dysfunction and leading to heart disease.
NAD deficiency can also disrupt the balance between anabolic and catabolic processes in the body, which leads to disturbances in body weight, insulin sensitivity and overall metabolic health.
Lastly, NAD+ is intricately involved in maintaining mitochondrial function and cellular repair mechanisms.
Reduced NAD levels can impair mitochondrial respiration and increase oxidative stress, and oxidative damage and DNA mutations can further exacerbate metabolic dysfunction and increase the risk of chronic diseases like diabetes and obesity.
If you, like us, are astounded at how interconnected all six of these causes of aging are, we strongly advocate for testing not just your NAD, but up to 23 biomarkers with our advanced panel, one of the most advanced biomarker tests available in the world.
Lastly, if you’re interested in going deeper on health-related content, here are a few of our recent posts that you may want to read:
P.S. Want to boost your intracellular NAD levels? Try a 2 week trial of our Jinfiniti Vitality Boost (do 2 scoops per day), use the discount code Blog15 if you’re a new customer for 15% off your 1st order).
Boost your NAD levels to optimize your health and longevity. Get an exclusive 20% OFF today by using code Blog20.Click here to order.
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