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Bcomplex

Bcomplex

Bcomplex

Bcomplex

Bcomplex

Bcomplex

Bcomplex

BioActive B Complex with TMG

Methylation and Homocysteine Support Supplement

Support the pathways that keep your metabolism moving. Methylation is a biochemical process your body uses every day. It helps process homocysteine, supports normal nervous-system function, and contributes to the way cells make and use energy. This formula pairs bioactive B vitamins with TMG, a naturally occurring methyl donor, to support those connected pathways.

The most bioavailable B vitamin forms for maximum absorption
Methylation, homocysteine metabolism, and everyday cellular energy support
Support the nutrient-conversion processes that help cells produce energy

Frequently Bought Together

Vitality ↑® NAD+ Booster Lozenge

Vitality ↑® NAD+ Booster Lozenge

provides precursors for your cells to make NAD, a coenzyme essential for the production of cellular energy and many other critical health function.

Vital Minerals is a comprehensive blend of essential nutrients designed to supp…

This Formula Is For You If

You want methylation support in active, ready-to-use forms*
You’ve been told you carry an MTHFR variant and aren’t sure what to do about it*
You’re tracking homocysteine and want to address it nutritionally*
You’re taking an NAD+ supplement and want to support methyl balance alongside it*
You want B vitamins your body doesn’t have to convert first

Homocysteine metabolism support through two separate pathways*
Methylation and detoxification support*
Active coenzyme forms that skip the conversion step*
Cellular energy support from B2, B6, and B12*
Cognitive and nervous system support*

Recommended Usage

Take 2 capsules per day, or as directed by your healthcare professional
Best taken with food, in the morning
Store in a cool, dry place
If you take an NAD+ precursor, take both consistently rather than cycling one

Supplement Facts

Serving Size: 2 Capsules Servings Per Container: 45

	Amount Per Serving	%Daily Value
Riboflavin (Vitamin B2 from Riboflavin-5-Phosphate)	12.5 mg	962%
Vitamin B6 (as Pyridoxal-5-Phosphate)	12.5 mg	735%
Folate (as 1000mcg, L-5-Methyltetrahydrofolate)	1666 mcg DFE	417%
Vitamin B12 (as Methylcobalamin)	1000 mcg	41,667%
Trimethylglycine (as Betaine Anhydrous)	500 mg	†

† Daily Value not established.

Other Ingredients: Vegetable Capsule, Organic Nu-FLOW®

Quality & Safety

Third-party tested for purity in every batch
Made in FDA-registered, cGMP facilities
GMO Free
Gluten Free
Vegan

Methylation support in active, ready-to-use forms

NAD Level Changes Timeline

Methylation is a delivery system, not a mystery

Methylation is your body passing around a small chemical tag called a methyl group. That tag turns genes on and off, builds neurotransmitters, repairs DNA, and clears compounds your liver needs to get rid of.

The cycle depends on recycling. Every time a methyl group gets handed off, what’s left behind is homocysteine, an amino acid your body has to convert back into something useful. When that conversion slows down, homocysteine accumulates. That’s why it shows up on longevity panels as a marker worth watching.

Homocysteine is a readout of a process, not the process itself.

How our formula works

Your body has two ways to recycle homocysteine.

The first uses folate and B12, with riboflavin and B6 supporting the surrounding reactions. The second is a backup route that uses trimethylglycine (TMG) to hand homocysteine a methyl group directly. Most B complexes only address the first route. This one covers both.

Riboflavin matters more than most people expect. It’s the cofactor for MTHFR, the enzyme that produces the active form of folate. Research suggests riboflavin status is a meaningful modifier of outcomes in people carrying the common MTHFR 677TT variant, which affects roughly 10% of some populations and up to a third of others.

The Ingredients

Active forms. Chosen for how the pathway actually works.

L-5-Methyltetrahydrofolate

1000mcg

The circulating, biologically active form of folate. It goes straight into the methylation cycle without needing MTHFR to convert it first. Research in human vessels indicates that 5-MTHF availability, rather than homocysteine itself, tracks with endothelial function.

See the research

Methylcobalamin

1000mcg

The methyl-carrying form of B12 and the direct partner to folate in homocysteine recycling. B12 absorption depends on a multi-step process involving stomach acid, pancreatic enzymes, and intrinsic factor, and that process becomes less reliable with age, after bariatric surgery, and with several common digestive conditions. Higher oral doses help compensate.

See the research

Trimethylglycine

500 mg (as Betaine Anhydrous)

The methyl donor for the second homocysteine pathway. In a 12-week randomized controlled trial, adults with elevated homocysteine who took low-dose B vitamins with 1g of betaine daily saw an average reduction of about 10% compared with placebo.

See the research

Pyridoxal-5-Phosphate

12.5mg

The active coenzyme form of B6. It runs the transsulfuration pathway, the third exit route for homocysteine, which converts it into cysteine rather than recycling it. When cellular P5P availability drops, that exit narrows.

See the research

Riboflavin-5-Phosphate

12.5mg

The cofactor MTHFR depends on. Suboptimal riboflavin status is more common in developed countries than most people assume, and randomized trials summarized in a 2016 review reported meaningful blood pressure reductions with riboflavin supplementation specifically in adults with the MTHFR 677TT genotype.

See the research

Real stories.
Real measurable change.

From gut health to glowing skin to healthy weight loss—our
customers are seeing real, sustainable changes with clean, effective formulas.

Founder, Aluma Wellness

Improved energy in 4 weeks

Lolli Brands Entertainment

Improved energy in 4 weeks

Suzanne Von Schaack

Film Producer, Actress, Modeling Coach

Improved energy in 4 weeks

Gymnast, Olympain & Hall of Fame Inductee

Improved energy in 4 weeks

Former Wbc USA Super Middleweight Champion

Improved energy in 4 weeks

JINFINITI’S PROMISE

Backed by 40 years of research & innovation.

Our scientific advisory board includes a dozen leading scientists and medical experts, such as presidents or officers of prominent medical societies, including Anti-Aging (A4M), Diabetes (ADA), Chiropractors (ACARC), Gerontology (GRG), and Sports Medicine.

Trusted by over 2,000 doctors and recommended to their patients, our supplements are endorsed by elite athletes like Olympian Celera Barnes, the world’s 16th fastest runner, and Tez Steinberg, the ultra-endurance athlete who solo-rowed from California to Hawaii.

40+

Academic research

22,000+

Citations by peers

$100M+

Research funding

Efficacy guarantee

If Vitality Boost doesn’t raise your NAD levels in 30 days, we’ll help you figure out why and guide you toward the right solution.

60 day money back guarantee

If your NAD level can not be increased by our Vitality Boost, we will be glad to refund your supplement purchase.

cGMP Certified

Our supplements are produced at a GMP-certified manufacturing facility, ensuring quality, safety and consistency.

Your questions,
answered.

Helpful explanations to give you a deeper
understanding of Jinfiniti’s tests, results, and
science.

Curious About NAD? Let’s Talk.

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hello@jinfiniti.com

What is methylation?

Methylation is how your cells attach a small chemical tag to other molecules. That single action regulates gene expression, builds neurotransmitters like serotonin and dopamine, supports DNA repair, and helps your liver process compounds for clearance. It happens constantly, which is why the raw materials matter.

What is TMG and why is it in a B complex?

Trimethylglycine, also called betaine, is a methyl donor. Your body recycles homocysteine through two pathways. One uses folate and B12. The other uses TMG. Including both means the formula supports the full cycle rather than half of it.

Why methylfolate instead of folic acid?

Folic acid is a synthetic form that requires enzymatic conversion before your cells can use it, and the enzyme responsible is MTHFR. L-5-methyltetrahydrofolate is already the converted form, so it enters the cycle directly.

Do I need this if I have an MTHFR variant?

Common MTHFR variants can reduce how efficiently your body produces active folate. Active-form supplementation is one reasonable response. It isn’t the only variable, though, and genotype alone doesn’t tell you where your homocysteine sits. Test it, then decide with your clinician.

Should I take this alongside Vitality↑® NAD+ Booster?

Many people do. NAD+ metabolism and methylation draw on overlapping resources, and if you’re supplementing NAD+ long term, homocysteine is a marker worth tracking. Talk with your clinician about what makes sense for your protocol.

Is 1000 mcg of B12 too much?

B12 has no established upper limit, and excess is excreted rather than stored to a harmful degree. High oral doses are used because passive absorption is inefficient, so only a small fraction of what you take actually crosses.

When should I take it?

Two capsules daily with food, ideally in the morning. Some people find B vitamins mildly stimulating, so evening dosing is less common.

Can I take this with a multivitamin?

You can, but check the labels. If your multivitamin already contains folic acid and B12, you may be doubling up unnecessarily. Restraint is part of precision. Take what you need and no more.

Are there side effects?

B vitamins are generally well tolerated at these amounts. Some people notice mild nausea if they take them without food. If you’re on methotrexate, levodopa, or medication for a seizure disorder, talk with your clinician before starting, since B vitamins can interact with all three.