{"id":22091,"date":"2024-11-12T09:00:00","date_gmt":"2024-11-12T14:00:00","guid":{"rendered":"https:\/\/www.jinfiniti.com\/blog\/?p=22091"},"modified":"2025-12-18T09:14:46","modified_gmt":"2025-12-18T14:14:46","slug":"nad-levels-by-age","status":"publish","type":"post","link":"https:\/\/www.jinfiniti.com\/blog\/nad-levels-by-age\/","title":{"rendered":"NAD Levels by Age Group: What&#8217;s Considered Normal?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Your body is a vast metropolis, with billions of cells working around the clock to keep you alive and thriving. At the heart of this cellular city lies NAD+ ( short for nicotinamide adenine dinucleotide) \u2013 the power currency that keeps your cellular economy from entering a recession.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Just as a city needs electricity to function, every cell in your body needs NAD+ to convert food into energy, repair damaged DNA, and regulate your biological clock. This coenzyme helps your cells perform over 500 different biochemical reactions, making it one of the most important players in healthy aging and overall wellness.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Unfortunately, our bodies&#8217; levels of NAD naturally decline as we age, dropping by up to 50% between our 20s and 80s. This decline is linked to many of the telltale signs of aging, from decreased energy levels to slower recovery after exercise. Understanding what&#8217;s &#8220;normal&#8221; for NAD+ levels at different ages can help us better grasp why we feel the way we do as time passes, and potentially, what we can do about it.<\/p>\n\n\n<style>.kadence-column22091_004af4-22 > .kt-inside-inner-col{padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-right:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);padding-left:var(--global-kb-spacing-md, 2rem);}.kadence-column22091_004af4-22 > .kt-inside-inner-col{border-top:1px solid #000000;border-right:1px solid #000000;border-bottom:5px solid #000000;border-left:1px solid #000000;}.kadence-column22091_004af4-22 > .kt-inside-inner-col,.kadence-column22091_004af4-22 > .kt-inside-inner-col:before{border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;}.kadence-column22091_004af4-22 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column22091_004af4-22 > .kt-inside-inner-col{flex-direction:column;}.kadence-column22091_004af4-22 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column22091_004af4-22 > .kt-inside-inner-col{background-color:rgba(230, 234, 245, 0.35);}.kadence-column22091_004af4-22 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column22091_004af4-22{position:relative;}@media all and (max-width: 1024px){.kadence-column22091_004af4-22 > .kt-inside-inner-col{border-top:1px solid #000000;border-right:1px solid #000000;border-bottom:5px solid #000000;border-left:1px solid #000000;flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column22091_004af4-22 > .kt-inside-inner-col{border-top:1px solid #000000;border-right:1px solid #000000;border-bottom:5px solid #000000;border-left:1px solid #000000;flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column22091_004af4-22\"><div class=\"kt-inside-inner-col\">\n<h3 class=\"wp-block-heading\">What You Should Know<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>NAD+ levels drop by 40-50% between your 20s and age 50, contributing to fatigue, slower recovery, and increased disease risk.<\/li>\n\n\n\n<li>Optimal NAD+ levels fall between 40-100\u03bcM, with anything below 40\u03bcM considered suboptimal or deficient.<\/li>\n\n\n\n<li>Men typically have higher baseline NAD+ levels than women, but experience steeper declines after age 60.<\/li>\n\n\n\n<li>Lifestyle changes like exercise and diet may not fully counter age-related NAD+ decline, making targeted supplementation necessary for optimal levels.<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">NAD+ and Aging<\/h2>\n\n\n<style>.kb-image22091_019ce7-ec .kb-image-has-overlay:after{opacity:0.3;border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;}.kb-image22091_019ce7-ec img.kb-img, .kb-image22091_019ce7-ec .kb-img img{border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;}<\/style>\n<div class=\"wp-block-kadence-image kb-image22091_019ce7-ec\"><figure class=\"aligncenter size-full kb-image-is-ratio-size\"><div class=\"kb-is-ratio-image kb-image-ratio-land169\"><img loading=\"lazy\" decoding=\"async\" width=\"605\" height=\"340\" src=\"https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2024\/11\/nad-and-aging-couple.jpg\" alt=\"Middle-aged couple holding hands by the lake\" class=\"kb-img wp-image-22094\" title=\"\" srcset=\"https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2024\/11\/nad-and-aging-couple.jpg 605w, https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2024\/11\/nad-and-aging-couple-480x270.jpg 480w, https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2024\/11\/nad-and-aging-couple-600x337.jpg 600w\" sizes=\"(max-width: 605px) 100vw, 605px\" \/><\/div><\/figure><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Your body&#8217;s NAD+ levels follow a predictable pattern throughout life \u2013 and unfortunately, it&#8217;s a downward trend. Research shows that NAD+ levels peak during our early 20s and then begin a steady decline, with most people experiencing a 40-50% drop by age 50. But why does this happen? The answer lies in a perfect storm of biological events.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As we age, certain enzymes, particularly PARPs and CD38, become increasingly active and hungry for NAD+<sup data-fn=\"4238b541-7660-470e-866c-e95d91401d0d\" class=\"fn\"><a id=\"4238b541-7660-470e-866c-e95d91401d0d-link\" href=\"#4238b541-7660-470e-866c-e95d91401d0d\">1<\/a><\/sup>. PARPs ramp up their activity to repair age-related DNA damage, while CD38 levels rise as part of our body&#8217;s inflammatory response to aging. It&#8217;s like having more bills to pay but with the same paycheck \u2013 something has to give.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the same time, our body&#8217;s ability to produce new NAD+ takes a hit. The molecular building blocks (or precursors) that we use to make NAD+ become less available, and the cellular machinery (biosynthetic enzymes) that assembles these pieces slows down<sup data-fn=\"2730a68f-5f2a-4e05-b7da-dea7796acd41\" class=\"fn\"><a id=\"2730a68f-5f2a-4e05-b7da-dea7796acd41-link\" href=\"#2730a68f-5f2a-4e05-b7da-dea7796acd41\">2<\/a><\/sup>. It&#8217;s similar to a factory facing both parts shortages and aging equipment \u2013 production inevitably drops.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This decline in NAD+ levels has real consequences for how we age. When cells can&#8217;t maintain healthy NAD+ levels, their energy production falters, DNA repair slows down, and cellular stress responses become sluggish. These changes contribute to many hallmarks of aging, from decreased muscle strength and slower wound healing to increased susceptibility to age-related diseases like cardiovascular problems and neurodegenerative conditions.<\/p>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">The Timeline of NAD+ Decline<\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1008\" height=\"840\" src=\"https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2024\/11\/gif-hf3mzzsedflkp3o6iffe.gif\" alt=\"Visual gif chart of NAD+ levels decline by age group\" class=\"wp-image-24109\" title=\"\"><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Infancy &amp; Childhood (0-12 years)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>NAD+ levels are naturally high and stable<\/li>\n\n\n\n<li>Peak production supports rapid growth and development<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Adolescence &amp; Young Adulthood (13-30 years)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Levels reach their lifetime peak in early 20s<\/li>\n\n\n\n<li>Optimal cellular energy and repair functions<\/li>\n\n\n\n<li>Gradual decline begins around age 25<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Middle Age (31-60 years)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Sharp decline begins<\/li>\n\n\n\n<li>Most dramatic drop occurs between 40-49 years<sup data-fn=\"c7d4c1d4-6bb7-485d-a335-95c6aece8053\" class=\"fn\"><a id=\"c7d4c1d4-6bb7-485d-a335-95c6aece8053-link\" href=\"#c7d4c1d4-6bb7-485d-a335-95c6aece8053\">3<\/a><\/sup><\/li>\n\n\n\n<li>Average person loses 40-50% of young adult levels by age 50<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Senior Years (60+ years)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Levels can drop to 1-10% of youthful amounts<\/li>\n\n\n\n<li>By age 80, typical levels are less than half those at age 40<\/li>\n\n\n\n<li>Continued gradual decline without intervention<\/li>\n<\/ul>\n\n\n<style>.kadence-column22091_de8df4-bb > .kt-inside-inner-col{padding-top:var(--global-kb-spacing-xs, 1rem);padding-right:var(--global-kb-spacing-xs, 1rem);padding-bottom:var(--global-kb-spacing-xs, 1rem);padding-left:var(--global-kb-spacing-xs, 1rem);}.kadence-column22091_de8df4-bb > .kt-inside-inner-col{border-top:2px solid rgba(223,211,255,0.3);border-right:2px solid rgba(223,211,255,0.3);border-bottom:2px solid rgba(223,211,255,0.3);border-left:2px solid rgba(223,211,255,0.3);}.kadence-column22091_de8df4-bb > .kt-inside-inner-col,.kadence-column22091_de8df4-bb > .kt-inside-inner-col:before{border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;}.kadence-column22091_de8df4-bb > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column22091_de8df4-bb > .kt-inside-inner-col{flex-direction:column;}.kadence-column22091_de8df4-bb > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column22091_de8df4-bb > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column22091_de8df4-bb{position:relative;}@media all and (max-width: 1024px){.kadence-column22091_de8df4-bb > .kt-inside-inner-col{border-top:2px solid rgba(223,211,255,0.3);border-right:2px solid rgba(223,211,255,0.3);border-bottom:2px solid rgba(223,211,255,0.3);border-left:2px solid rgba(223,211,255,0.3);flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column22091_de8df4-bb > .kt-inside-inner-col{border-top:2px solid rgba(223,211,255,0.3);border-right:2px solid rgba(223,211,255,0.3);border-bottom:2px solid rgba(223,211,255,0.3);border-left:2px solid rgba(223,211,255,0.3);flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column22091_de8df4-bb\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap{align-content:center;}:where(.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:center;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap{column-gap:var(--global-kb-gap-sm, 1rem);row-gap:var(--global-kb-gap-sm, 1rem);padding-top:0px;padding-right:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:0px;padding-left:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}.kb-row-layout-id22091_73912d-5e > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap{grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(1 of *:not(style)){order:2;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(2 of *:not(style)){order:1;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(3 of *:not(style)){order:12;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(4 of *:not(style)){order:11;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(5 of *:not(style)){order:22;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(6 of *:not(style)){order:21;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(7 of *:not(style)){order:32;}.kb-row-layout-id22091_73912d-5e > .kt-row-column-wrap > .wp-block-kadence-column:nth-child(8 of *:not(style)){order:31;}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id22091_73912d-5e aligncenter wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-left-golden kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-middle\">\n<style>.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{display:flex;}.kadence-column22091_8ec76c-04 > .kt-inside-inner-col,.kadence-column22091_8ec76c-04 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}.kadence-column22091_8ec76c-04 > .kt-inside-inner-col > .aligncenter{width:100%;}.kt-row-column-wrap > .kadence-column22091_8ec76c-04{align-self:center;}.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_8ec76c-04{align-self:auto;}.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}.kadence-column22091_8ec76c-04 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column22091_8ec76c-04{position:relative;}@media all and (max-width: 1024px){.kt-row-column-wrap > .kadence-column22091_8ec76c-04{align-self:center;}}@media all and (max-width: 1024px){.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_8ec76c-04{align-self:auto;}}@media all and (max-width: 1024px){.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 1024px){.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kt-row-column-wrap > .kadence-column22091_8ec76c-04{align-self:center;}.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_8ec76c-04{align-self:auto;}.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}.kadence-column22091_8ec76c-04 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column22091_8ec76c-04\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading22091_fcea0e-2c, .wp-block-kadence-advancedheading.kt-adv-heading22091_fcea0e-2c[data-kb-block=\"kb-adv-heading22091_fcea0e-2c\"]{max-width:75%;margin-right:auto;margin-left:auto;margin-bottom:0px;text-align:center;font-size:var(--global-kb-font-size-sm, 0.9rem);font-style:normal;background-color:rgba(223,211,255,0.26);border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;}.wp-block-kadence-advancedheading.kt-adv-heading22091_fcea0e-2c mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading22091_fcea0e-2c[data-kb-block=\"kb-adv-heading22091_fcea0e-2c\"] mark.kt-highlight{font-style:normal;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading22091_fcea0e-2c img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading22091_fcea0e-2c[data-kb-block=\"kb-adv-heading22091_fcea0e-2c\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading22091_fcea0e-2c wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading22091_fcea0e-2c\">CLIA-Certified NAD Test Kit<\/p>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading22091_9bea50-da, .wp-block-kadence-advancedheading.kt-adv-heading22091_9bea50-da[data-kb-block=\"kb-adv-heading22091_9bea50-da\"]{text-align:center;font-size:28px;font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading22091_9bea50-da mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading22091_9bea50-da[data-kb-block=\"kb-adv-heading22091_9bea50-da\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading22091_9bea50-da img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading22091_9bea50-da[data-kb-block=\"kb-adv-heading22091_9bea50-da\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading22091_9bea50-da wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading22091_9bea50-da\">Test your NAD+ levels from home.<\/p>\n\n\n<style>.wp-block-kadence-advancedbtn.kb-btns22091_3cebf2-73{gap:var(--global-kb-gap-xs, 0.5rem );justify-content:center;align-items:center;}.kt-btns22091_3cebf2-73 .kt-button{font-weight:normal;font-style:normal;}.kt-btns22091_3cebf2-73 .kt-btn-wrap-0{margin-right:5px;}.wp-block-kadence-advancedbtn.kt-btns22091_3cebf2-73 .kt-btn-wrap-0 .kt-button{color:#555555;border-color:#555555;}.wp-block-kadence-advancedbtn.kt-btns22091_3cebf2-73 .kt-btn-wrap-0 .kt-button:hover, .wp-block-kadence-advancedbtn.kt-btns22091_3cebf2-73 .kt-btn-wrap-0 .kt-button:focus{color:#ffffff;border-color:#444444;}.wp-block-kadence-advancedbtn.kt-btns22091_3cebf2-73 .kt-btn-wrap-0 .kt-button::before{display:none;}.wp-block-kadence-advancedbtn.kt-btns22091_3cebf2-73 .kt-btn-wrap-0 .kt-button:hover, .wp-block-kadence-advancedbtn.kt-btns22091_3cebf2-73 .kt-btn-wrap-0 .kt-button:focus{background:#444444;}<\/style>\n<div class=\"wp-block-kadence-advancedbtn kb-buttons-wrap kb-btns22091_3cebf2-73\"><style>ul.menu .wp-block-kadence-advancedbtn .kb-btn22091_4d6a8c-c8.kb-button{width:initial;}.wp-block-kadence-advancedbtn .kb-btn22091_4d6a8c-c8.kb-button{color:#ffffff;background:#000000;font-family:Jost;font-weight:400;border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;box-shadow:1px 1px 3px 0px rgba(0, 0, 0, 0.2);}<\/style><a class=\"kb-button kt-button button kb-btn22091_4d6a8c-c8 kt-btn-size-standard kt-btn-width-type-auto kb-btn-global-fill kt-btn-has-text-true kt-btn-has-svg-false wp-block-kadence-singlebtn\" href=\"https:\/\/www.jinfiniti.com\/product\/intracellular-nad-test\/\"><span class=\"kt-btn-inner-text\">Get the NAD+ Test<\/span><\/a><\/div>\n<\/div><\/div>\n\n\n<style>.kadence-column22091_6babe8-1f > .kt-inside-inner-col{display:flex;}.kadence-column22091_6babe8-1f > .kt-inside-inner-col,.kadence-column22091_6babe8-1f > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column22091_6babe8-1f > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column22091_6babe8-1f > .kt-inside-inner-col{flex-direction:column;justify-content:center;align-items:center;}.kadence-column22091_6babe8-1f > .kt-inside-inner-col > .kb-image-is-ratio-size{align-self:stretch;}.kadence-column22091_6babe8-1f > .kt-inside-inner-col > .wp-block-kadence-advancedgallery{align-self:stretch;}.kadence-column22091_6babe8-1f > .kt-inside-inner-col > .aligncenter{width:100%;}.kt-row-column-wrap > .kadence-column22091_6babe8-1f{align-self:center;}.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_6babe8-1f{align-self:auto;}.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_6babe8-1f > 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.wp-block-kadence-column.kadence-column22091_6babe8-1f{align-self:auto;}.kt-inner-column-height-full:not(.kt-has-1-columns) > .wp-block-kadence-column.kadence-column22091_6babe8-1f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}.kadence-column22091_6babe8-1f > .kt-inside-inner-col{flex-direction:column;justify-content:center;align-items:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column22091_6babe8-1f kb-section-dir-vertical\"><div class=\"kt-inside-inner-col\"><style>.kb-image22091_918a3c-ef .kb-image-has-overlay:after{opacity:0.3;border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;}.kb-image22091_918a3c-ef img.kb-img, .kb-image22091_918a3c-ef .kb-img img{border-top-left-radius:10px;border-top-right-radius:10px;border-bottom-right-radius:10px;border-bottom-left-radius:10px;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image22091_918a3c-ef kb-image-is-ratio-size\"><div class=\"kb-is-ratio-image kb-image-ratio-land43\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2025\/10\/nad-test-cta-new.png\" alt=\"Jinfiniti Intracellular NAD Test on purple background\" class=\"kb-img wp-image-46013\" title=\"\" srcset=\"https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2025\/10\/nad-test-cta-new.png 800w, https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2025\/10\/nad-test-cta-new-480x360.png 480w, https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2025\/10\/nad-test-cta-new-768x576.png 768w, https:\/\/www.jinfiniti.com\/blog\/wp-content\/uploads\/2025\/10\/nad-test-cta-new-600x450.png 600w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/div><\/figure>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">What are Normal NAD Levels by Age Group?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Inside our cells, NAD concentrations can range from as low as 10 \u03bcM to as high as 1000 \u03bcM<sup data-fn=\"ac54f306-12e3-4d50-a932-ad7ad5fad370\" class=\"fn\"><a id=\"ac54f306-12e3-4d50-a932-ad7ad5fad370-link\" href=\"#ac54f306-12e3-4d50-a932-ad7ad5fad370\">4<\/a><\/sup>. To put this in perspective, imagine filling a drop of water with different amounts of NAD &#8211; some cells maintain just a trace amount, while others keep a abundant supply, depending on their specific energy needs. When measured in tissue samples, researchers have found total NAD concentrations between 0.3 and 0.4 \u03bcmol\/g.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Based on Dr. Jin-Xiong She&#8217;s clinical research, we now have clear benchmarks for interpreting intracellular NAD levels:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Severely deficient:<\/strong> 0-20\u03bcM<\/li>\n\n\n\n<li><strong>Deficient:<\/strong> 20-30\u03bcM<\/li>\n\n\n\n<li><strong>Suboptimal:<\/strong> 30-40\u03bcM<\/li>\n\n\n\n<li><strong>Optimal:<\/strong> 40-100\u03bcM<\/li>\n\n\n\n<li><strong>Too high:<\/strong> Above 100\u03bcM (may not provide additional benefits and could potentially be harmful)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">These <strong>optimal ranges of 40-100\u03bcM<\/strong> are the sweet spot where NAD-dependent enzymes, including sirtuins and PARPs, can function most effectively.<\/p>\n\n\n\n<!DOCTYPE html>\n<html lang=\"en\">\n<head>\n    \n    \n    <title>Tissue-Specific NAD+ Decline<\/title>\n    <style>\n        \/* Reset styles only within widget to prevent affecting blog text *\/\n        .nad-widget * {\n            box-sizing: border-box;\n            margin: 0;\n            padding: 0;\n            font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', sans-serif;\n            font-weight: normal; \/* Explicitly reset font weight *\/\n        }\n        \n        .nad-widget {\n            color: #2A2A3A;\n            line-height: 1.5;\n            font-size: 14px;\n            max-width: 600px;\n            margin: 0 auto;\n            background-color: white;\n            border-radius: 8px;\n            box-shadow: 0 4px 12px rgba(0, 0, 0, 0.04);\n            overflow: hidden;\n        }\n        \n        .nad-widget .nad-widget-header {\n            padding: 15px;\n            background: linear-gradient(to right, #7EB6FF, #A387D8);\n            color: white;\n            text-align: center;\n        }\n        \n        .nad-widget .nad-widget-header p {\n            font-size: 18px;\n            font-weight: 600;\n            margin: 0;\n            color: white;\n        }\n        \n        .nad-widget .nad-tabs {\n            display: flex;\n            border-bottom: 1px solid #F0F2F8;\n        }\n        \n        .nad-widget .nad-tab {\n            flex: 1;\n            padding: 10px 5px;\n            text-align: center;\n            cursor: pointer;\n            transition: all 0.2s ease;\n            font-size: 14px;\n            border-bottom: 2px solid transparent;\n        }\n        \n        .nad-widget .nad-tab.active {\n            border-bottom: 2px solid #A387D8;\n            font-weight: 500;\n            color: #6C4A9E;\n        }\n        \n        .nad-widget .nad-tab:hover:not(.active) {\n            background-color: #F0F2F8;\n        }\n        \n        .nad-widget .nad-content {\n            padding: 15px;\n            display: none;\n        }\n        \n        .nad-widget .nad-content.active {\n            display: block;\n        }\n        \n        .nad-widget .tissue-item {\n            margin-bottom: 16px;\n        }\n        \n        .nad-widget .tissue-header {\n            font-weight: 600;\n            font-size: 14px;\n            margin-bottom: 5px;\n            color: #4B6FBF;\n        }\n        \n        .nad-widget .tissue-desc {\n            font-size: 12px;\n            margin-bottom: 8px;\n        }\n        \n        .nad-widget .decline-bar {\n            height: 16px;\n            background: #F0F2F8;\n            border-radius: 8px;\n            margin: 8px 0;\n            position: relative;\n            overflow: hidden;\n        }\n        \n        .nad-widget .decline-fill {\n            height: 100%;\n            border-radius: 8px;\n            width: 0;\n            transition: width 0.7s ease;\n        }\n        \n        .nad-widget .low {\n            background: linear-gradient(90deg, #7EB6FF 0%, #5D95FF 100%);\n        }\n        \n        .nad-widget .medium {\n            background: linear-gradient(90deg, #5D95FF 0%, #A387D8 100%);\n        }\n        \n        .nad-widget .high {\n            background: linear-gradient(90deg, #A387D8 0%, #8667C0 100%);\n        }\n        \n        .nad-widget .variable {\n            background: linear-gradient(90deg, #7EB6FF 0%, #A387D8 50%, #8667C0 100%);\n        }\n        \n        .nad-widget .decline-label {\n            position: absolute;\n            right: 8px;\n            top: 50%;\n            transform: translateY(-50%);\n            color: #2A2A3A;\n            font-weight: 500;\n            font-size: 11px;\n            z-index: 1;\n        }\n        \n        .nad-widget .footer-note {\n            padding: 10px 15px;\n            font-size: 11px;\n            color: #666;\n            background-color: #F0F2F8;\n            text-align: center;\n        }\n    <\/style>\n<\/head>\n<body>\n    <div class=\"nad-widget\">\n        <div class=\"nad-widget-header\">\n            <p>Tissue-Specific NAD+ Decline<\/p>\n        <\/div>\n        \n        <div class=\"nad-tabs\">\n            <div class=\"nad-tab active\" data-tab=\"rodent\">Rodent Studies<\/div>\n            <div class=\"nad-tab\" data-tab=\"human\">Human Studies<\/div>\n        <\/div>\n        \n        <div class=\"nad-content active\" id=\"rodent\">\n            <div class=\"tissue-item\">\n                <div class=\"tissue-header\">Skeletal Muscle<\/div>\n                <div class=\"decline-bar\">\n                    <div class=\"decline-fill high\" data-width=\"65\"><\/div>\n                    <span class=\"decline-label\">15-65% Decline<\/span>\n                <\/div>\n                <div class=\"tissue-desc\">Consistent decrease with age in rodents, particularly in the gastrocnemius muscle.<\/div>\n            <\/div>\n            \n            <div class=\"tissue-item\">\n                <div class=\"tissue-header\">Liver Tissue<\/div>\n                <div class=\"decline-bar\">\n                    <div class=\"decline-fill medium\" data-width=\"50\"><\/div>\n                    <span class=\"decline-label\">10-50% Decline<\/span>\n                <\/div>\n                <div class=\"tissue-desc\">Variable patterns with age. Most studies report decline in aged rodents with some exceptions.<\/div>\n            <\/div>\n            \n            <div class=\"tissue-item\">\n                <div class=\"tissue-header\">Cardiac Tissue<\/div>\n                <div class=\"decline-bar\">\n                    <div class=\"decline-fill variable\" data-width=\"65\"><\/div>\n                    <span class=\"decline-label\">0-65% Decline<\/span>\n                <\/div>\n                <div class=\"tissue-desc\">Highly variable pattern. Study differences likely reflect species, strains, and methodological approaches.<\/div>\n            <\/div>\n            \n            <div class=\"tissue-item\">\n                <div class=\"tissue-header\">Brain Regions<\/div>\n                <div class=\"decline-bar\">\n                    <div class=\"decline-fill medium\" data-width=\"45\"><\/div>\n                    <span class=\"decline-label\">Variable by Region<\/span>\n                <\/div>\n                <div class=\"tissue-desc\">Declines earlier than other tissues. Different brain regions show distinct patterns.<\/div>\n            <\/div>\n        <\/div>\n        \n        <div class=\"nad-content\" id=\"human\">\n            <div class=\"tissue-item\">\n                <div class=\"tissue-header\">Skin Tissue<\/div>\n                <div class=\"decline-bar\">\n                    <div class=\"decline-fill high\" data-width=\"50\"><\/div>\n                    <span class=\"decline-label\">\u226550% Decline<\/span>\n                <\/div>\n                <div class=\"tissue-desc\">Substantial reductions with age. Strong negative correlations between NAD+ levels and age in both genders.<\/div>\n            <\/div>\n            \n            <div class=\"tissue-item\">\n                <div class=\"tissue-header\">Brain &#038; Cerebrospinal Fluid<\/div>\n                <div class=\"decline-bar\">\n                    <div class=\"decline-fill low\" data-width=\"25\"><\/div>\n                    <span class=\"decline-label\">10-25% Decline<\/span>\n                <\/div>\n                <div class=\"tissue-desc\">Approximately 14% decrease in subjects older than 45 years compared to younger subjects.<\/div>\n            <\/div>\n            \n            <div class=\"tissue-item\">\n                <div class=\"tissue-header\">Blood NAD+ Levels<\/div>\n                <div class=\"decline-bar\">\n                    <div class=\"decline-fill medium\" data-width=\"35\"><\/div>\n                    <span class=\"decline-label\">Decline before age 50<\/span>\n                <\/div>\n                <div class=\"tissue-desc\">More pronounced decline in men than women, especially in middle age (40-49 years).<\/div>\n            <\/div>\n        <\/div>\n        \n        <div class=\"footer-note\">\n            Note: NAD+ decline varies significantly across tissues, species, and genders. Data based on multiple research studies.\n        <\/div>\n    <\/div>\n    \n    <script>\n        \/\/ Tab switching\n        document.querySelectorAll('.nad-tab').forEach(tab => {\n            tab.addEventListener('click', () => {\n                const tabId = tab.getAttribute('data-tab');\n                \n                \/\/ Deactivate all tabs and contents\n                document.querySelectorAll('.nad-tab').forEach(t => t.classList.remove('active'));\n                document.querySelectorAll('.nad-content').forEach(c => c.classList.remove('active'));\n                \n                \/\/ Activate selected tab and content\n                tab.classList.add('active');\n                document.getElementById(tabId).classList.add('active');\n            });\n        });\n        \n        \/\/ Animate decline bars on load\n        document.addEventListener('DOMContentLoaded', () => {\n            setTimeout(() => {\n                document.querySelectorAll('.decline-fill').forEach(bar => {\n                    const width = bar.getAttribute('data-width') + '%';\n                    bar.style.width = width;\n                });\n            }, 300);\n        });\n    <\/script>\n<\/body>\n<\/html>\n\n\n\n<h3 class=\"wp-block-heading\">Measuring Your NAD Levels<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Clinical evidence suggests that suboptimal NAD levels may contribute to various health challenges &#8211; from <a href=\"https:\/\/www.jinfiniti.com\/blog\/chronic-fatigue-supplements\/\">chronic fatigue<\/a> and sleep disturbances to cognitive decline and metabolic disorders.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Modern&nbsp;methods like Jinfiniti&#8217;s <a href=\"https:\/\/www.jinfiniti.com\/product\/intracellular-nad-test\/\">Intracellular NAD Test<\/a> now allow for precise measurement of cellular NAD concentrations through convenient at-home collection, enabling individuals to assess their personal NAD status and work to optimize their levels and address <a href=\"https:\/\/www.jinfiniti.com\/blog\/nad-deficiency-symptoms\/\">NAD deficiency symptoms<\/a> through targeted interventions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The Gender Gap in Age-Specific NAD+ Levels<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Studies have consistently shown that men tend to have higher baseline levels of whole blood NAD+ compared to women. In one large-scale study of over 1,500 participants, the average NAD+ level in men was 34.5 \u03bcmol\/L, while women averaged 31.3 \u03bcmol\/L<sup data-fn=\"37e2a3a7-9b67-4c4f-a993-1f536f7ad253\" class=\"fn\"><a id=\"37e2a3a7-9b67-4c4f-a993-1f536f7ad253-link\" href=\"#37e2a3a7-9b67-4c4f-a993-1f536f7ad253\">5<\/a><\/sup>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">However, the way NAD+ levels change with age differs significantly between the sexes:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In men, NAD+ levels tend to decline gradually with age, with a more pronounced drop observed after age 60<\/li>\n\n\n\n<li>Women, on the other hand, show a more complex pattern. Their NAD+ levels fluctuate across age groups without a clear downward trend<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The distinct NAD+ profiles between men and women suggest that hormones play a role in regulating NAD+ metabolism. Researchers speculate that female sex hormones, particularly estrogen, may help maintain NAD+ levels throughout a woman&#8217;s life. This hypothesis is supported by observations in post-menopausal women, whose NAD+ patterns begin to resemble those of men.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The gender gap in NAD+ levels and their age-related changes may have far-reaching implications for how men and women age:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Higher NAD+ levels in men might provide them with a metabolic advantage in youth, but the steeper decline with age could contribute to accelerated aging in some aspects.<\/li>\n\n\n\n<li>The more stable NAD+ levels in women could potentially offer some protection against certain age-related diseases, though more research is needed to confirm this.<\/li>\n\n\n\n<li>The effectiveness of NAD+ boosting supplements or therapies may differ between men and women, necessitating gender-specific approaches to anti-aging treatments<sup data-fn=\"e0203ba2-386a-4516-9b34-7a950811dbd7\" class=\"fn\"><a id=\"e0203ba2-386a-4516-9b34-7a950811dbd7-link\" href=\"#e0203ba2-386a-4516-9b34-7a950811dbd7\">6<\/a><\/sup>.<\/li>\n<\/ol>\n\n\n\n<h2 class=\"wp-block-heading\">Strategies for Increasing NAD+ Levels as You Age<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">While many people seek to <a href=\"https:\/\/www.jinfiniti.com\/blog\/increase-nad-levels\/\">naturally increase NAD levels<\/a> through lifestyle modifications like exercise, intermittent fasting, and consuming NAD-rich foods, research shows these methods alone can&#8217;t fully counter age-related NAD+ decline. It&#8217;s like trying to fill a leaking bucket \u2013 as we age, our cells&#8217; increasing demand for NAD+ outpaces what we can restore through lifestyle changes alone.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A more comprehensive approach involves strategic supplementation with <a href=\"https:\/\/www.jinfiniti.com\/blog\/nad-boosters\/\">NAD boosters<\/a> that target the root cause of age-related NAD+ decline. The key lies in providing your body with the right precursors in the right combinations to optimize NAD+ production at the cellular level.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Recent clinical research has revealed that a synergistic approach yields better results than single-compound solutions. This breakthrough understanding led to the development of <a title=\"\" href=\"https:\/\/www.jinfiniti.com\/product\/vitality-nad-plus-booster-supplement-powder\/\"><strong>Vitality \u2191\u00ae NAD+ Booster<\/strong><\/a>, Jinfiniti&#8217;s scientifically formulated combination of NMN, Creatine monohydrate, D-Ribose, and Nicotinamide. Each component plays a crucial role:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>NMN serves as a direct NAD+ precursor<\/li>\n\n\n\n<li>Creatine monohydrate supports energy metabolism<\/li>\n\n\n\n<li>D-Ribose enhances cellular energy production<\/li>\n\n\n\n<li>Nicotinamide helps regulate NAD+ consumption<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">What sets this formulation apart is its extensive validation \u2013 from clinical studies to real-world testing in hundreds of clinics. The data speaks for itself: approximately 85% of users achieve optimized NAD+ levels, as confirmed through clinical testing. This high success rate demonstrates that while aging&#8217;s effects on NAD+ levels are inevitable, they&#8217;re not irreversible.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Think of maintaining healthy NAD+ levels as a long-term investment in your cellular health. While lifestyle factors provide the foundation, targeted supplementation with clinically validated NAD boosters offers the most reliable way to maintain optimal NAD+ levels as you age. The key is choosing a solution backed by both scientific research and real-world results.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Referenced Sources<\/h2>\n\n\n<ol class=\"wp-block-footnotes\"><li id=\"4238b541-7660-470e-866c-e95d91401d0d\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S004763742100141X\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S004763742100141X<\/a> <a href=\"#4238b541-7660-470e-866c-e95d91401d0d-link\" aria-label=\"Jump to footnote reference 1\">\u21a9\ufe0e<\/a><\/li><li id=\"2730a68f-5f2a-4e05-b7da-dea7796acd41\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5795269\/\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5795269\/<\/a> <a href=\"#2730a68f-5f2a-4e05-b7da-dea7796acd41-link\" aria-label=\"Jump to footnote reference 2\">\u21a9\ufe0e<\/a><\/li><li id=\"c7d4c1d4-6bb7-485d-a335-95c6aece8053\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8979162\/\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8979162\/<\/a> <a href=\"#c7d4c1d4-6bb7-485d-a335-95c6aece8053-link\" aria-label=\"Jump to footnote reference 3\">\u21a9\ufe0e<\/a><\/li><li id=\"ac54f306-12e3-4d50-a932-ad7ad5fad370\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6482912\/\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6482912\/<\/a> <a href=\"#ac54f306-12e3-4d50-a932-ad7ad5fad370-link\" aria-label=\"Jump to footnote reference 4\">\u21a9\ufe0e<\/a><\/li><li id=\"37e2a3a7-9b67-4c4f-a993-1f536f7ad253\"><a href=\"https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2022.829658\/full\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2022.829658\/full<\/a> <a href=\"#37e2a3a7-9b67-4c4f-a993-1f536f7ad253-link\" aria-label=\"Jump to footnote reference 5\">\u21a9\ufe0e<\/a><\/li><li id=\"e0203ba2-386a-4516-9b34-7a950811dbd7\"><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.13965\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.13965<\/a> <a href=\"#e0203ba2-386a-4516-9b34-7a950811dbd7-link\" aria-label=\"Jump to footnote reference 6\">\u21a9\ufe0e<\/a><\/li><\/ol>","protected":false},"excerpt":{"rendered":"<p>Your body is a vast metropolis, with billions of cells working around the clock to keep you alive and thriving. At the heart of this cellular city lies NAD+ ( short for nicotinamide adenine dinucleotide) \u2013 the power currency that keeps your cellular economy from entering a recession.&nbsp; Just as a city needs electricity to [&hellip;]<\/p>\n","protected":false},"author":10909,"featured_media":22104,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"[{\"content\":\"<a href=\\\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S004763742100141X\\\" target=\\\"_blank\\\" rel=\\\"noopener\\\" title=\\\"\\\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S004763742100141X<\/a>\",\"id\":\"4238b541-7660-470e-866c-e95d91401d0d\"},{\"content\":\"<a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5795269\/\\\" target=\\\"_blank\\\" rel=\\\"noopener\\\" title=\\\"\\\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5795269\/<\/a>\",\"id\":\"2730a68f-5f2a-4e05-b7da-dea7796acd41\"},{\"content\":\"<a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8979162\/\\\" target=\\\"_blank\\\" rel=\\\"noopener\\\" title=\\\"\\\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8979162\/<\/a>\",\"id\":\"c7d4c1d4-6bb7-485d-a335-95c6aece8053\"},{\"content\":\"<a href=\\\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6482912\/\\\" target=\\\"_blank\\\" rel=\\\"noopener\\\" title=\\\"\\\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6482912\/<\/a>\",\"id\":\"ac54f306-12e3-4d50-a932-ad7ad5fad370\"},{\"content\":\"<a href=\\\"https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2022.829658\/full\\\" target=\\\"_blank\\\" rel=\\\"noopener\\\" title=\\\"\\\">https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2022.829658\/full<\/a>\",\"id\":\"37e2a3a7-9b67-4c4f-a993-1f536f7ad253\"},{\"content\":\"<a href=\\\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.13965\\\" target=\\\"_blank\\\" rel=\\\"noopener\\\" title=\\\"\\\">https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.13965<\/a>\",\"id\":\"e0203ba2-386a-4516-9b34-7a950811dbd7\"}]"},"categories":[351,342,352,371],"tags":[],"class_list":["post-22091","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nad-supplement-interventions","category-nad","category-nad-precursors","category-premature-aging"],"_links":{"self":[{"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/posts\/22091","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/users\/10909"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/comments?post=22091"}],"version-history":[{"count":0,"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/posts\/22091\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/media\/22104"}],"wp:attachment":[{"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/media?parent=22091"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/categories?post=22091"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.jinfiniti.com\/blog\/wp-json\/wp\/v2\/tags?post=22091"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}