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3 Secrets From the Blue Zones and NAD

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In case you haven’t heard, Blue Zones are all the rage right now. I highly recommend Netflix’s Live to 100: Secrets of the Blue Zones, a documentary series that highlights the journalistic research of National Geographic Explorer, Dan Buettner, who discovered places in the world where healthspan and lifespan were unusually long. 

Without us personally lab-testing the individuals who live in the Blue Zones, we think it’s safe to surmise that, given their longevity and vitality, the NAD levels among these special centenarians and other elderly individuals must be remarkably high. But what does the data say? 

In this email, armed with research from thousands of tests I have conducted and studies I have supervised of people from all over the world, I’ll explain why I believe NAD and Blue Zones are inextricably linked. 

There are five consistent, crossover elements of all Blue Zones and they are the following: 

  • A Balanced Diet
  • Active Lifestyle and Natural Movement 
  • Strong Social Connections and Community Engagement 
  • Moderation and Caloric Restriction 
  • Purpose and a Sense of Belonging 

But did you know that at least three of these five elements have a significant amount to do with NAD? 

Here’s why: 

1. A Balanced Diet and NAD 

seniors eating healthy food - jinfiniti precision medicine

In each of the Blue Zones, diet plays a significant role in differentiating between these areas and the rest of the world. 

In Japan’s Blue Zone of Okinawa, purple sweet potatoes are a staple of the residents’ diets, affording them rich supplies of antioxidants, phytonutrients, and gut-promoting fiber. 

Sardinians eat a diet rich in garden vegetables, fruits and limited meat and animal products from their locally raised goats and sheep. 

Costa Rica’s Blue Zone diet consists of primarily squash, rice, beans and corn, with occasional tropical fruits and meat products.

The one thing each Blue Zone has in common when it comes to diet is that it is 95% plant-based. But what does that have to do with the anti-aging coenzyme, NAD? 

Plant-based diets may influence Nicotinamide Adenine Dinucleotide (NAD) levels positively because many plant-based foods are rich in precursors to NAD, such as tryptophan, niacin, and nicotinamide riboside. These precursors often convert into NAD within the body, and they’re crucial for cellular energy metabolism. You can support the biosynthesis of your body’s naturally occurring NAD by eating an array of these nutrient-dense foods. 

Even though they are eaten somewhat less in most of the Blue Zones, meats also contain large quantities of at least one precursor to NAD—niacin. 

Lean, sustainably-raised meat eaten in balance with a predominantly plant-based diet spans a couple of the Blue Zones. For the diets that are sourced entirely from plants, legumes offer the niacin instead of meat. 

You can support your NAD levels and aid your vital cellular functions simply by embracing a diverse, plant-heavy diet. 

2. Active Lifestyle and Natural Movement 

seniors exercising - jinfiniti precision medicine

Physical activity is seamlessly integrated into the daily lives of Blue Zone inhabitants. Walking, gardening, and other forms of natural movement are an integral part of their routine. Active transportation such as walking or cycling is also utilized over sedentary modes. This constant, gentle activity promotes mobility, muscle strength, and cardiovascular health, all of which contribute to the longevity and well-being of the residents.  

But as we stress so often here at Jinfiniti, an active lifestyle is intricately linked to the levels and utilization of your body’s NAD. When you’re exercising, the demand for energy in your cells surges. Your body requires more ATP, the energy molecule that fuels cellular processes, and NAD plays a big role in the pathways that generate ATP.  NAD, acting as the critical player in cellular respiration and energy production, becomes of vital importance to meet your increased energy demand when you are physically exerting yourself.

Regular physical activity has been shown to elevate NAD levels in the body, which can lead to various health benefits beyond simple mitochondrial function, including enhanced metabolism and even longevity. 

NAD is also linked to sirtuins, a class of proteins involved in cellular health and longevity, and these also can be activated by physical activity. Sirtuins play a critical role in DNA repair, inflammation regulation and stress response. 

The long and short of it? Moving is good for you. It can help your body create its own NAD. And every Blue Zone in the world has consistent physical activity built into the residents’ daily rituals. 

3. Moderation and Caloric Restriction 

 - jinfiniti precision medicine

This element may not sound quite as fun as some of the others (looking at you, Strong Social Connections) but it’s worth mentioning because of its incredible benefits. 

Each of the Blue Zones practice forms of moderation in their daily eating habits. Every Blue Zone (except for the Adventists) practice moderate alcohol consumption. The Okinawans say a 2500-year-old Confucian mantra before their meals to remind themselves to stop eating when their stomachs are 80 percent full.

People in the Blue Zones also eat their smallest meals in the late afternoon or early evening, and then they don’t eat anything else for the rest of the day. 

But the connection to NAD is interesting. 

Studies have shown that caloric restriction, often associated with extending lifespan and promoting health span, could impact NAD levels positively. Caloric restriction may enhance NAD levels by upregulating enzymes involved in NAD synthesis. As calorie intake decreases, your body can allocate resources towards crucial cellular processes, including NAD biosynthesis. 

So according to NAD research and the Blue Zone data, while getting enough calories is vital for your body’s optimal health, so is making sure you aren’t eating too many. 

Based on the incredible connections between NAD and the Blue Zones alone, it’s clear that NAD plays a significant role in longevity and healthspan. Of course, we also know this from the thousands of tests and research studies we’ve conducted. 

We also know that our formula will optimize—not just improve—intracellular NAD for 90% of people alone, which no other NAD supplement can come close to promising.

And that’s because no other supplement on the market compares to the quality and efficacy of Jinfiniti’s Accuri® Vitality Boost

That’s why we confidently back it with a 30-day Money Back and Efficacy Guarantee.

Lastly, if you’re interested in going deeper on health-related content, here are a few of our recent posts that you may want to read:

  1. What Does Peak Performance Look Like? 
  2. 9 Powerful Benefits of Optimizing Your NAD
  3. Andrew Huberman is Wrong About NAD, NMN & Longevity
  4. Why Optimized, Precision Medicine is the Future

P.S. Want to boost your intracellular NAD levels? Try a 2 week trial of our Jinfiniti Vitality Boost (do 2 scoops per day), use the discount code welcome20 if you’re a new customer for 20% off your 1st order).